Research Topics
| Tai Long PanSummaryAffiliation: Chang Gung University Country: Taiwan Publications
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Detail Information
Publications
Inhibitory effects of Scutellaria baicalensis extract on hepatic stellate cells through inducing G2/M cell cycle arrest and activating ERK-dependent apoptosis via Bax and caspase pathwayTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan
J Ethnopharmacol 139:829-37. 2012..The bioactive components extracted from Scutellaria baicalensis Georgi (SB) have been widely used for anti-cancer, anti-oxidation, anti-inflammation and modulating the immune response...- Functional proteomics reveals hepatotoxicity and the molecular mechanisms of different forms of chromium delivered by skin administrationTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
Proteomics 12:477-89. 2012..These signature networks represent an approach to discover novel relationships in complex data, and functional proteomics of liver may provide solid evidence of chromium-caused hepatic damage via the skin... - Expression, by functional proteomics, of spontaneous tolerance in rat orthotopic liver transplantationTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Kwei Shan, Tao Yuan, Taiwan
Immunology 113:57-64. 2004..Furthermore, the serum proteome map could provide guidance with respect to discovering potential protein targets in OLT tolerance and eventually prolong hepatic allograft survival in the future... - Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cellsTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
Proteomics 10:914-29. 2010..The possible contributions of these proteins to the cytotoxicity of tanshinone IIA provide potential opportunities for the development of cancer therapeutics... - Skin toxicology of lead species evaluated by their permeability and proteomic profiles: a comparison of organic and inorganic leadTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan
Toxicol Lett 197:19-28. 2010..Lead presented a biphasic pattern on cell growth and intracellular ATP content, with a stimulating effect at low concentrations and an inhibitory effect on cell proliferation at higher concentrations... - Functional proteomics reveal the effect of Salvia miltiorrhiza aqueous extract against vascular atherosclerotic lesionsYu Chiang Hung
Graduate Institute of Clinical Medical Sciences, Kaohsiung Division, Chang Gung University, Taiwan
Biochim Biophys Acta 1804:1310-21. 2010..These signature networks and functional proteomics highlighted herein may facilitate the evaluation of potential therapeutic targets and elucidate novel mechanisms through which protein functions can be regulated by the redox status... - Antiviral effects of Salvia miltiorrhiza (Danshen) against enterovirus 71Bin Wen Wu
Department of Biochemistry, Chang Gung University, Taoyuan 333, Taiwan, ROC
Am J Chin Med 35:153-68. 2007..We conclude that danshen extracts possess antiviral activity and have potential for the development as an anti-enterovirus 71 agent... - Prospective highlights of serum glycoproteins in spontaneous tolerance after orthotopic liver transplantationTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
Clin Chim Acta 412:604-13. 2011..We examined the effects and the mechanisms of serum glycoproteins on spontaneous tolerance after orthotopic liver transplantation (OLT) between DA (RT-1(a)) and PVG (RT-1(c)) rats... - Elucidation of the percutaneous absorption of chromium compounds by functional proteomicsTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, 259 Wen Hwa 1st Road, Kweishan, Taoyuan, Taiwan
Proteomics 9:5120-31. 2009..In addition, functional proteomics of skin tissues may provide a promising tool for developing therapeutic strategies and can serve as the basis for further research... - Protective effects of Danshen (Salvia miltiorrhiza) on adriamycin-induced cardiac and hepatic toxicity in ratsJyh Sheng You
Chang Gung University School of Traditional Chinese Medicine, Kweishan, Taiwan, China
Phytother Res 21:1146-52. 2007..In contrast, administration of DS before and concurrent with ADR significantly attenuated these effects. In conclusion, DS is potentially protective against ADR-induced cardiac and hepatic toxicity... - Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatmentYu Chiang Hung
Graduate Institute of Clinical Medical Sciences, Kaohsiung Division, Chang Gung University, Kaohsiung, Taiwan
J Ethnopharmacol 124:463-74. 2009.... - Systematic evaluations of skin damage irradiated by an erbium:YAG laser: histopathologic analysis, proteomic profiles, and cellular responseTai Long Pan
School of Traditional Chinese Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan
J Dermatol Sci 58:8-18. 2010..The erbium:yttrium-aluminum-garnet (Er:YAG) laser is used for surgical resurfacing. It has ablative properties with water as its main chromophore... - Proteomic profiling of oxidative stress in human victims of traffic-related injuries after lower limb revascularization and indication for secondary amputationChih Hung Lin
Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao Yuan, Taiwan
J Pharm Biomed Anal 51:784-94. 2010.... - Characterization of plasma protein profiles from patients with neurofibromatosis IPei Wen Wang
Chang Gung Molecular Medicine Research Center, Chang Gung University, Tao Yuan, Taiwan
Clin Chim Acta 380:139-44. 2007..We compared plasma protein profiles between normal controls and NF1 patients for yielding important insights into the mechanisms underlying NF1 related tumor formation and diagnostic biomarkers to classify the diverse clinical symptoms... - Anthranilic acid-based inhibitors of phosphodiesterase: design, synthesis, and bioactive evaluationYih Dih Cheng
Graduate Institute of Natural Products, Chang Gung University, Taoyuan, 33302, Taiwan
Org Biomol Chem 9:7113-25. 2011..Compound 49 could be approved as a lead for the development of new drugs in the treatment of neutrophilic inflammatory diseases... - Schisandra chinensis protects against adriamycin-induced cardiotoxicity in ratsJyh Sheng You
School of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taipe, ROC
Chang Gung Med J 29:63-70. 2006..Schisandra (SC) has strong antioxidant activity. We investigate the protective effects of SC on adriamycin-induced cardiotoxicity... - A useful model to audit liver resolution from cirrhosis in rats using functional proteomicsErh Hao Liu
Department of Surgery, Chang Gung Memorial Hospital, School of Traditional Chinese Medicine, Taipei, Taiwan
J Surg Res 138:214-23. 2007..We conducted a rat cirrhosis and recovery model, on the basis of which proteomics was used to audit liver resolution from cirrhosis... - Association of nucleophosmin/B23 mRNA expression with clinical outcome in patients with bladder carcinomaKe-Hung Tsui
Chang Gung Genomics Research Center, Chang Gung University, Tao-Yuan, Taiwan, Republic of China
Urology 64:839-44. 2004..In patients with muscular invasion disease, overexpression of nucleophosmin/B23 mRNA was associated with the greatest risk of recurrence and progression, suggesting a potential rationale for early definitive therapy in these patients... - Erbium:YAG laser enhances transdermal peptide delivery and skin vaccinationWoan Ruoh Lee
Department of Dermatology, Taipei Medical University Hospital, Taipei, Taiwan
J Control Release 128:200-8. 2008..To reveal the mechanisms underlying these changes, a proteomic technique combined with mass spectrometry was used. This is, to our knowledge, the first report of a laser being used to immunize intact animals... - Breast tumor microenvironment: proteomics highlights the treatments targeting secretomeShui Tein Chen
Institute of Biological Chemistry and the Genomics Research Center, Academia Sinica, Taipei, Taiwan
J Proteome Res 7:1379-87. 2008..Such in vivo profiling of breast cancer secretomes may facilitate the development of novel drugs specifically targeting secretome... - Proteomic analysis of Down's syndrome patients with goutYing-Chou Chen
Department of Rheumatology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
Clin Chim Acta 369:89-94. 2006..However, decreased ApoA1 revealed a positive correlation between defective lipid metabolism and gouty arthritis in DS/G patients... - New insights into the pathological mechanisms of cerebrotendinous xanthomatosis in the Taiwanese using genomic and proteomic toolsPei Weg Wang
Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
Proteomics 6:1029-37. 2006..This is the first paper to integrate both genomic and proteomic concepts for analyzing the possible mechanism of CTX and provides more information for related study in the future... - Proteomics reveals protein profile changes in doxorubicin--treated MCF-7 human breast cancer cellsShui-Tein Chen
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
Cancer Lett 181:95-107. 2002..Modulation of HSP27 levels may be a clinically useful potential target for design of antitumor drugs and controlling breast tumor growth... - Biomic study of human myeloid leukemia cells differentiation to macrophages using DNA array, proteomic, and bioinformatic analytical methodsHsueh-Fen Juan
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
Electrophoresis 23:2490-504. 2002..This powerful holistic biomic approach using cDNA microarray, proteomics coupled to bioinformatics can provide in-depth information on the impact and importance of the regulated genes and proteins for HL-60 differentiation...