Research Topics
Species | Yhu Chering HuangSummaryAffiliation: Chang Gung Memorial Hospital Country: Taiwan Publications
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Publications
Nasal carriage of methicillin-resistant Staphylococcus aureus in contacts of an adolescent with community-acquired disseminated diseaseYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, 5 Fu Shin Street, Kweishan, Taoyuan, Taiwan
Pediatr Infect Dis J 23:919-22. 2004....
Molecular epidemiology of clinical isolates of methicillin-resistant Staphylococcus aureus in TaiwanYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Kweishan, Taoyuan, Taiwan
J Clin Microbiol 42:307-10. 2004..The other 26 types (30 type-subtypes) were minor. We conclude that the majority of MRSA clinical isolates shared a common PFGE pattern, indicating the presence of a single, epidemic MRSA clone prevailing in major hospitals in Taiwan...
Community-associated meticillin-resistant Staphylococcus aureus in children in Taiwan, 2000sYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Kweishan, Taoyuan, Taiwan
Int J Antimicrob Agents 38:2-8. 2011..The information provided here is not only important for local public health but can also enhance a general understanding of the successful epidemic clones of CA-MRSA worldwide...
Influenza-associated central nervous system dysfunction in Taiwanese children: clinical characteristics and outcomes with and without administration of oseltamivirYhu Chering Huang
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Kweishan, Taoyan, Taiwan
Pediatr Infect Dis J 28:647-8. 2009..Seventeen children received oseltamivir therapy after admission and no significant difference between administration of oseltamivir and outcome was observed (P = 0.1512 by Fisher exact test)...
Association of Staphylococcus aureus colonization in parturient mothers and their babiesYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
Pediatr Infect Dis J 28:742-4. 2009..aureus isolates, 11 (50%) paired isolates were unrelated, 1 pair related, and 10 pairs (45%) indistinguishable. Newborn babies acquire S. aureus colonization soon after birth either from the environment or their mothers...
Genotyping analysis of colonizing candidal isolates from very-low-birthweight infants in a neonatal intensive care unitY C Huang
Division of Paediatric Infectious Diseases, Chang Gung Children s Hospital, Chang Gung University, 5, Fu Shin Street, Kweishan, Taoyuan, Taiwan
J Hosp Infect 58:200-3. 2004..Should an infant harbour a candidal strain, they may harbour this strain at multiple sites and for a prolonged period...
Significance of coagulase-negative staphylococci isolated from a single blood culture from neonates in intensive careYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Kweishan, Taiwan
Ann Trop Paediatr 26:311-8. 2006..Coagulase-negative staphylococci (CoNS) are the most common pathogens of late-onset bacteraemia in neonatal intensive care units (NICUs). Discriminating true infection from contamination is difficult...
Nasal carriage of methicillin-resistant Staphylococcus aureus in school children without identifiable risk factors in northern taiwanYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Kweishan, Taoyuan, Taiwan
Pediatr Infect Dis J 24:276-8. 2005..One common genotype accounted for most isolates from the school children and from the HCWs. Based on genotyping, MRSA strains circulating in the community in Taiwan were similar to the hospital strains...
Molecular surveillance of clinical methicillin-resistant Staphylococcus aureus isolates in neonatal intensive care unitsYhu Chering Huang
Chang Gung University, Kweishan, Taoyuan, Taiwan
Infect Control Hosp Epidemiol 26:157-60. 2005..aureus clinical isolates. The objective of this study was to assess the relatedness of these MRSA strains...
Toxic shock syndrome in children: epidemiology, pathogenesis, and managementYu Yu Chuang
Department of Pediatrics, St Mary s Hospital, Lotung, Taiwan
Paediatr Drugs 7:11-25. 2005..An adjuvant therapeutic strategy may include agents that can block superantigens, such as intravenous immunoglobulin that contains superantigen neutralizing antibodies...
Methicillin-resistant Staphylococcus aureus colonization and its association with infection among infants hospitalized in neonatal intensive care unitsYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, 5 Fu Shin St, Kweishan, Taoyuan, Taiwan
Pediatrics 118:469-74. 2006..We conducted this study to assess the rate of methicillin-resistant Staphylococcus aureus colonization and its association with infection among infants hospitalized in methicillin-resistant S aureus-endemic NICUs...
Changing molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates from a teaching hospital in Northern TaiwanYhu Chering Huang
Division of Pediatrics Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
J Clin Microbiol 44:2268-70. 2006..The changing epidemiology is due to the introduction of a new epidemic clone (sequence type 5) and a local community clone (sequence type 59) of MRSA into the hospital...
Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control studyYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
Acta Paediatr Taiwan 46:156-60. 2005..8 (95% CI 2.95-145.4, p =.002). Conclusively, two major clones of MRSA prevailed in our NICUs, and the presence of skin infection at onset was the risk factor for the acquisition of MRSA bacteremia in these infants...
Determining the significance of coagulase-negative staphylococci identified in cultures of paired blood specimens from neonates by species identification and strain clonalityYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
Infect Control Hosp Epidemiol 27:70-3. 2006..Isolation of CoNS in cultures of 2 blood samples obtained simultaneously from separate sites in neonates usually represents true infection...
Prevalence of methicillin-resistant Staphylococcus aureus nasal colonization among Taiwanese children in 2005 and 2006Yhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital and Chang Gung Memorial Hospital at Linko, Kaohsiung, Taiwan
J Clin Microbiol 45:3992-5. 2007..We concluded that between 2005 and 2006, 7.3% of healthy Taiwanese children were colonized by MRSA in nares. MRSA harbored in healthy children indicates an accelerated spread in the community...
Outbreak of Shigella sonnei gastroenteritis in Northeastern TaiwanYu Yu Chuang
Departments of Pediatrics, St Mary s Hospital, Lo Tung, I Lan, Taiwan
Pediatr Infect Dis J 25:92-4. 2006..5, 32 and 27%, respectively. None of the isolates was resistant to ciprofloxacin. Prolonged bacterial shedding in the feces can occur when an inappropriate antibiotic is used...
Comparative molecular analysis of community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus isolates from children in northern TaiwanY C Huang
Division of Paediatric Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
Clin Microbiol Infect 14:1167-72. 2008..However, the CA clone of ST59 was also identified in a substantial proportion of HA isolates...
Community-acquired Pseudomonas aeruginosa sepsis in previously healthy infants and children: analysis of forty-three episodesYhu Chering Huang
Divisions of Pediatric Infectious Diseases, Chang Gung Children s Hospital, School of Medicine, Chang Gung University, Taoyuan, Taiwan
Pediatr Infect Dis J 21:1049-52. 2002..Fewer than 50 cases of community-acquired sepsis associated with P. aeruginosa in previously healthy infants and children have been reported in English language literature...
Outbreak of Acinetobacter baumannii bacteremia in a neonatal intensive care unit: clinical implications and genotyping analysisYhu Chering Huang
Division of Pediatric Infectious Disease, Taipei Branch, Chang Gung Children s Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 21:1105-9. 2002..Outbreaks of sepsis associated with have been rarely reported in neonatal intensive care units (NICUs). We describe such an outbreak in a NICU, and the results of molecular epidemiologic investigations are presented...
Nasal carriage of methicillin-resistant Staphylococcus aureus in household contacts of children with community-acquired diseases in TaiwanYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 26:1066-8. 2007..aureus infection and 30 (25%) of 121 household contacts. By genotyping comparison, 94% and 64% of the colonization isolates from the patients and the contacts, respectively, were indistinguishable from the clinical isolates...
Influenza A-associated central nervous system dysfunction in children presenting as transient visual hallucinationYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, 5 Fu Shin Street, Kweishan, Taoyuan, Taiwan
Pediatr Infect Dis J 22:366-8. 2003..Within 8 days all five children were discharged in stable condition. Influenza A-associated central nervous system dysfunction may be more common than previously recognized, and the prognosis is not necessarily poor...
Outcome of enterovirus 71 infections with or without stage-based management: 1998 to 2002Luan Yin Chang
Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University, 5 Fu Hsing Street, Kweishan, Taoyuan, Taiwan
Pediatr Infect Dis J 23:327-32. 2004..In Taiwan in 1998 almost all the EV71 patients with cardiopulmonary failure died. To improve clinical outcome of EV71 patients, we developed a stage-based management program in 2000...
Safety and immunogenicity of a diphtheria, tetanus, and acellular pertussis-inactivated poliovirus vaccine/Haemophilus influenzae type B combination vaccine administered to Taiwanese infants at 2, 4, and 6 months of ageTzou Yien Lin
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taipei
Chang Gung Med J 26:315-22. 2003....
Transmission and clinical features of enterovirus 71 infections in household contacts in TaiwanLuan Yin Chang
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Kweishan, Taiwan
JAMA 291:222-7. 2004..Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality, its transmission has not been thoroughly investigated...
Clinical features and molecular characteristics of invasive community-acquired methicillin-resistant Staphylococcus aureus infections in Taiwanese childrenChih Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan 333, Taiwan
Diagn Microbiol Infect Dis 59:287-93. 2007..Surgical interventions were often required, and a prolonged course of antibiotic therapy was needed. A multiresistant CA-MRSA clone characterized as ST59 was identified from these children in Taiwan...
Comparison of clinical features between coxsackievirus A2 and enterovirus 71 during the enterovirus outbreak in Taiwan, 2008: a children's hospital experienceShih Perng Chen
Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Medical Center, Taoyuan, Taiwan
J Microbiol Immunol Infect 43:99-104. 2010..In this study, we compared Cox A2 with enterovirus 71 (EV71) in terms of clinical manifestation and epidemiology during the 2008 enterovirus outbreak in Taiwan...
One-year post-primary antibody persistence and booster immune response to a fully liquid five-component acellular pertussis, diphtheria, tetanus, inactivated poliomyelitis, Haemophilus influenzae type b conjugate vaccineTzou Yien Lin
Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University Medicine, Taoyuan, Taipei, Taiwan
Int J Infect Dis 11:488-95. 2007....
Nasal carriage of Streptococcus pneumoniae in healthy children and adults in northern TaiwanChih Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Kweishan 333, Taoyuan, Taiwan
Diagn Microbiol Infect Dis 59:265-9. 2007..The isolates from the children attending the CCC had a significantly higher penicillin-nonsusceptible rate than those from the pupils and adolescents. Transmission of the same clone in a single class may have frequently occurred...
Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in TaiwanCheng Hsun Chiu
Department of Pediatrics, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
Antimicrob Agents Chemother 51:3404-6. 2007..Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance...
Nontyphoidal Salmonella bacteremia in previously healthy children: analysis of 199 episodesMing Han Tsai
Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan
Pediatr Infect Dis J 26:909-13. 2007..Nontyphoidal Salmonella (NTS) bacteremia is not rare in otherwise healthy children in Taiwan. Few studies described the clinical manifestations and outcomes of NTS bacteremia in previously healthy children...
Change in the molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream infections in TaiwanChih Jung Chen
Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, 333, Taoyuan, Taiwan
Diagn Microbiol Infect Dis 65:199-201. 2009..Multiresistance might be one of the characteristics that could have contributed to its quick adaptation to hospital environments...
Nasopharyngeal carriage of Streptococcus pneumoniae in Taiwan before and after the introduction of a conjugate vaccineChen Yen Kuo
Department of Pediatrics, Chang Gung Children s Hospital, College of Medicine, Chang Gung University, 5 Fu Hsin Street, Kwei Shan Hsiang, Taoyuan, Taiwan
Vaccine 29:5171-7. 2011..To evaluate the effect of the vaccination, we conducted an active, prospective, large-scale, long-term, and multicenter study to assess the prevalence of nasopharyngeal Streptococcus pneumoniae carriage in Taiwanese children...
Experience with linezolid therapy in children with osteoarticular infectionsChih Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 26:985-8. 2007..The clinical efficacy of this drug has not been previously evaluated for Gram-positive osteoarticular infections in children...
Risk factors of enterovirus 71 infection and associated hand, foot, and mouth disease/herpangina in children during an epidemic in TaiwanLuan Yin Chang
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University, Taoyuan, Taiwan
Pediatrics 109:e88. 2002..We measured EV71 seroprevalence rates before and after the epidemic and investigated risk factors associated with EV71 infection and illness...
The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and managementTzou Yien Lin
Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
Clin Infect Dis 34:S52-7. 2002..After poliovirus is eradicated, EV71 will become the most important enterovirus that affects children, and development of a vaccine may be the only effective measure against it...
Host and microbiologic factors associated with mortality in Taiwanese children with invasive pneumococcal diseases, 2001 to 2006Chih Jung Chen
Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
Diagn Microbiol Infect Dis 63:194-200. 2009..1; 95% CI, 1.4-47.3), which are the independent predictors for fatality. This finding highlighted the importance of immunization of disadvantaged children, targeting drug-resistant pneumococci...
Antibiotic resistance patterns of community-acquired urinary tract infections in children with vesicoureteral reflux receiving prophylactic antibiotic therapyChi Hui Cheng
Department of Pediatrics, Chang Gung Children s Hospital, and Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan
Pediatrics 122:1212-7. 2008..The goal was to examine bacterial antimicrobial resistance of recurrent urinary tract infections in children receiving antibiotic prophylaxis because of primary vesicoureteral reflux...
Seroprevalence of SARS Coronavirus Among Residents Near a Hospital with a Nosocomial OutbreakMing Han Tsai
Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, and Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taiwan
J Formos Med Assoc 107:885-91. 2008....
Clinical analysis of computed tomography-staged orbital cellulitis in childrenChen Fang Ho
Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan
J Microbiol Immunol Infect 40:518-24. 2007..This study sought to delineate the clinical, bacteriological and radiological findings, management and outcome of orbital cellulitis...
Successful control of methicillin-resistant Staphylococcus aureus in endemic neonatal intensive care units--a 7-year campaignYhu Chering Huang
Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan
PLoS ONE 6:e23001. 2011..Methicillin-resistant Staphylococcus aureus (MRSA) is among the most important nosocomial pathogens in the intensive care unit (ICU) worldwide, including Taiwan. Since 1997, our neonatal ICUs (NICUs) had become endemic for MRSA...
Complications associated with 2 different types of percutaneously inserted central venous catheters in very low birth weight infantsMing Horng Tsai
Division of Neonatology and Pediatric Hematology Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Yunlin, Taiwan
Infect Control Hosp Epidemiol 32:258-66. 2011....
A cluster of adenovirus serotype 3 infections in children in northern Taiwan: clinical features and laboratory findingsChien Hui Lin
Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Kweishan, Taoyuan, Taiwan
J Microbiol Immunol Infect 40:302-9. 2007..To define clinical manifestations and laboratory findings of adenovirus serotype 3 infections in children...
Renal abscess in children: a 10-year clinical and radiologic experience in a tertiary medical centerChi Hui Cheng
Division of Pediatric Nephrology, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Taiwan
Pediatr Infect Dis J 27:1025-7. 2008..Experiences gained from this 10-year study on patients with CT-proved diagnosis include the varied clinical presentations and use of sonographic-marked nephromegaly and focal mass as indications for further CT diagnosis...
Poststreptococcal glomerulonephritis with pulmonary edema presenting as respiratory distressChih Yung Chiu
Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University, Taoyuan, Taiwan
Pediatr Nephrol 19:1237-40. 2004..Prompt diagnosis and early therapy of PSGNmay avoid mortality and unnecessary therapeutic intervention...
Viral load in blood is correlated with disease severity of neonatal coxsackievirus B3 infection: early diagnosis and predicting disease severity is possible in severe neonatal enterovirus infectionMeng Hsiu Yen
Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
Clin Infect Dis 44:e78-81. 2007..Timely diagnosis is possible in severe neonatal enterovirus infection...
Factors associated with nasal colonization of methicillin-resistant Staphylococcus aureus among healthy children in TaiwanChih Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu Shin Street, Kweishan 333, Taoyuan, Taiwan
J Clin Microbiol 49:131-7. 2011..The carriage rate varied significantly across different demographical features. Crowding was an independent environmental risk factor that might accelerate CA-MRSA transmission in the community...
Chlamydial pneumonia in children requiring hospitalization: effect of mixed infection on clinical outcomeMing Han Tsai
Division of Pediatric Infectious Diseases, Chang Gung Children's Hospital, Taoyuan, Taiwan
J Microbiol Immunol Infect 38:117-22. 2005..8%) among these patients. The clinical course of chlamydial pneumonia was not serious in most patients, but alertness is needed to the possibility of developing severe pneumonia in cases with bacterial coinfection...
Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985-2010Wen I Lee
Primary Immunodeficiency Care and Research PICAR Institute, Chang Gung University College of Medicine and Chang Gung Memorial Hospital, Taoyuan, Taiwan
Immunobiology 216:1286-94. 2011..Awareness of under-diagnosis among physicians rather than pediatricians is vital for timely diagnosis and consequently adequate treatment...
Seroprevalence and severity of 2009 pandemic influenza A H1N1 in TaiwanChih Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
PLoS ONE 6:e24440. 2011..This study is to determine the seroprevalence of the pandemic influenza A H1N1 virus (pH1N1) in Taiwan before and after the 2009 pandemic, and to estimate the relative severity of pH1N1 infections among different age groups...
Booster vaccination at 6-8 years of age with a reduced antigen content dTpa-IPV vaccine is immunogenic and safe after priming with whole-cell pertussis vaccineTzou Yien Lin
Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan
Hum Vaccin 4:50-3. 2008....
Necrotizing pneumococcal pneumonia with bronchopleural fistula among children in TaiwanYu Chia Hsieh
Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 30:740-4. 2011..Histopathologic features of children receiving surgical resections of the lung because of BPF were analyzed to explore the pathogenesis of destructive lung disease caused by Streptococcus pneumoniae...
Clinical features of echovirus 6 and 9 infections in childrenHao Yuan Lee
Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan
J Clin Virol 49:175-9. 2010..Clinical features of echovirus 6 and 9 infections in children have not been comprehensively evaluated, particularly for sporadic cases...
Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES)Wen I Lee
Primary Immunodeficiency Care and Research PICAR Institute, Chang Gung Memorial Hospital and University College of Medicine, Taoyuan, Taiwan
Immunobiology 216:909-17. 2011..Close follow-up of the HIES phenotype rather than identifying genetic mutations should be the cornerstone of intervention at this juncture because of relatively lower percentage of identifying mutations in Taiwanese HIES (4/11; 36.5%)...
Molecular analysis of repeated methicillin-resistant Staphylococcus aureus infections in childrenChih Jung Chen
Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
PLoS ONE 5:e14431. 2010..The study aimed to define the genetic relatedness of MRSA isolates from children with repeated infections...
Seroprevalence of human papillomavirus types 16 and 18 in the general population in Taiwan: implication for optimal age of human papillomavirus vaccinationChih Jung Chen
Divisions of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu Shin Street, Kweishan 333, Taoyuan, Taiwan
J Clin Virol 38:126-30. 2007..The optimal age for administration of recently approved prophylactic human papillomavirus (HPV) vaccines remains undetermined...
Clinical and epidemiologic features of Coxsackievirus A6 infection in children in northern Taiwan between 2004 and 2009Shih Hsuan Lo
Department of Pediatrics, Children s Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
J Microbiol Immunol Infect 44:252-7. 2011..This study is to define clinical manifestations and laboratory findings of Cox A6 infection in children...
Clinical and genetic characterization of severe influenza B-associated diseases during an outbreak in TaiwanWen Chen Li
Division of Pediatric Infectious Diseases, Chang Gung Children s Hospital, Taoyuan, Taiwan
J Clin Virol 42:45-51. 2008..Mismatches between circulating and vaccine strains of influenza virus had been observed in Taiwan. A comprehensive clinical and genetic analysis of influenza B viruses-associated important diseases was lacking...
Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999Chung Guei Huang
Department of Laboratory Medicine, Chang Gung Memorial Hospital, 5 Fu Shin Street, Kweishan, Taoyuan, Taiwan
Arch Virol 155:343-50. 2010..In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV...
Bronchiolitis obliterans in children: clinical presentation, therapy and long-term follow-upChih Yung Chiu
Department of Pediatrics, Chang Gung Memorial Hospital, Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
J Paediatr Child Health 44:129-33. 2008..To delineate the predisposing factors, clinical, radiological features and outcomes of bronchiolitis obliterans (BO) in children for minimising morbidity and mortality...
A fully liquid diphtheria-tetanus-five component acellular pertussis-inactivated poliomyelitis--Haemophilus influenzae type b conjugate vaccine: immunogenicity and safety of primary vaccination in Taiwanese infantsTzou Yien Lin
Chang Gung Children s Hospital, Taoyuan, Taiwan
Int J Infect Dis 11:129-36. 2007....
Probiotics have clinical, microbiologic, and immunologic efficacy in acute infectious diarrheaChien Chang Chen
Division of Gastroenterology, Department of Pediatrics, Chang Gung Children s Hospital, Taiwan
Pediatr Infect Dis J 29:135-8. 2010..Acute infectious diarrhea is a major cause of childhood morbidity and economic burden for families. We evaluate the clinical, microbiologic, and immunologic effects of probiotics in acute infectious diarrhea...
Clinical features and genotyping analysis of community-acquired methicillin-resistant Staphylococcus aureus infections in Taiwanese childrenChih-Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang-Gung Children's Hospital, 5 Fu-Shin Street, 333, Taoyuan, Taiwan
Pediatr Infect Dis J 24:40-5. 2005..aureus infection, even community-acquired, a glycopeptide-containing regimen should be considered for initial empirical therapy in the case of serious infection...
Genetic characterization of enterovirus 71 isolated from patients with severe disease by comparative analysis of complete genomesShih Cheng Chang
Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan
J Med Virol 84:931-9. 2012..Further studies of EV71 pathogenesis should examine the significance of genomic diversity and the effects of multiple mutations in a viral population. J. Med. Virol. 84:931-939, 2012. © 2012 Wiley Periodicals, Inc...
Incidence density and relative risk of nosocomial infection in Taiwan's Only Children's Hospital, 1999-2003Suh Hwa Maa
School of Nursing, Chang Gung University, Linkou Chang Gung Children s Hospital, Tao Yuan, Taiwan, Republic of China
Infect Control Hosp Epidemiol 29:767-70. 2008..06 cases per 1,000 patient-days. The relative risk was highest in intensive care units, oncology wards, and neonatal observation wards. Very young, low-birth-weight, critically ill, and oncology patients were most at risk...
Invasive pediatric Neisseria meningitidis infectionsPao Lan Tuan
Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
J Microbiol Immunol Infect 42:427-32. 2009..However, the number of infections increased in 2001 and 2002. This study was performed to ascertain the epidemiology and clinical manifestations of infections caused by meningococcus in a pediatric population...
Epidemiology and clinical peculiarities of norovirus and rotavirus infection in hospitalized young children with acute diarrhea in Taiwan, 2009Shu yan Yang
Division of Pediatric Infectious Disease, Department of Pediatrics, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
J Microbiol Immunol Infect 43:506-14. 2010..We conducted a study to investigate the incidence of norovirus in young children hospitalized with acute diarrhea in Taiwan and its clinical peculiarity compared with rotavirus gastroenteritis...
Neonatal enterovirus infections: emphasis on risk factors of severe and fatal infectionsTzou-Yien Lin
Division of Pediatric Infecti=ious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 22:889-94. 2003....
Community-acquired methicillin-resistant Staphylococcus aureus in TaiwanChih-Jung Chen
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan
J Microbiol Immunol Infect 38:376-82. 2005..The treatment of putative CA S. aureus infection should be stratified according to the severity and the disease entity...
Bronchopleural cutaneous fistula due to Eikenella corrodensKin Sun Wong
Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
J Pediatr (Rio J) 81:265-7. 2005..The aim of this paper is to review the subject and to report on and discuss a case of bronchopleural cutaneous fistula due to Eikenella corrodens...
Boostrix: a reduced-dose acellular pertussis vaccine for use in adolescents and adultsWen Chen Li
Division of Pediatric Infectious Diseases, Children s Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan and Graduate School of Clinical Medicine, Taoyuan, Taiwan
Expert Rev Vaccines 8:1317-27. 2009..Nevertheless, we expect that the advent of Boostrix will lead to a much better control of pertussis in the general population...
National survey of invasive pneumococcal diseases in Taiwan under partial PCV7 vaccination in 2007: emergence of serotype 19A with high invasive potentialYu Chia Hsieh
Department of Pediatrics, Chang Gung Children s Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan
Vaccine 27:5513-8. 2009..7% of cases in children aged <2 years. Among patients aged >or=65 years, the 23-valent pneumococcal polysaccharide vaccine covered 70.4% of cases. In the future, a broader pneumococcal vaccine is needed...
Nontuberculous mycobacterial pulmonary disease in an immunocompetent adolescentKin Sun Wong
Department of Pediatric Respiratory Therapy, Chang Gung Children s Hospital, 5 Fu Hsin Street, Kweishan 333, Taoyuan, Taiwan
Respir Care 53:908-11. 2008..kansasii. Treating Mycobacterium in an immunocompetent child requires multiple antimycobacterial drugs, including isoniazid, rifampicin, and ethambutol for at least 12 months after negative sputum culture...
Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced diseaseWen I Lee
Primary Immunodeficiency Care and Research Institute, Chang Gung Memory Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan
J Clin Immunol 29:319-29. 2009..The aim of this study was to evaluate immunity in HIV-uninfected children with bacille Calmette-Guerin-induced disease (BCG-ID) over an 8-year period, with particular emphasis on underlying diseases...
Surveillance of respiratory viral infections among pediatric outpatients in northern TaiwanTzou-Yien Lin
Division of Pediatric Infectious Diseases, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kweishan, Taoyuan, Taiwan, ROC
J Clin Virol 30:81-5. 2004..Influenza viruses also can be identified throughout the year and during the epidemic, a child older than 5 years of age with acute febrile URTI is likely to be a case of influenza...
Clinical features of nosocomial infections by extended-spectrum beta-lactamase-producing Enterobacteriaceae in neonatal intensive care unitsShun Chiu
Division of Pediatric Infectious Diseases, Chang Gung University, Taoyuan, Taiwan
Acta Paediatr 94:1644-9. 2005..The risk factors for the acquisition of ESBL-producing enterobacterial infections in these infants were not identified in this series...
Neurodevelopment and cognition in children after enterovirus 71 infectionLuan Yin Chang
Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
N Engl J Med 356:1226-34. 2007..Enterovirus 71 is a common cause of hand, foot, and mouth disease and encephalitis in Asia and elsewhere. The long-term neurologic and psychiatric effects of this viral infection on the central nervous system (CNS) are not well understood...
Use of molecular assay in diagnosis of hand, foot and mouth disease caused by enterovirus 71 or coxsackievirus A 16Kuo Chien Tsao
School of Medical Technology, Chang Gung University, Kwei-Shan, 259 Wen-Hua 1st Road, Kwei-Shan, 333, Tao-Yuan, Taiwan, ROC
J Virol Methods 102:9-14. 2002....
Yersinia enterocolitica sepsis in an adolescent with Cooley's anemiaShun Chiu
Division of Pediatric Infectious Disease, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan
J Formos Med Assoc 102:202-4. 2003..Though Y. enterocolitica sepsis is rare in Taiwan, clinicians should be aware of its tendency to develop in patients with Cooley's anemia, fever and enterocolitis and that its clinical course may include sepsis leading to shock...
Duration of antimicrobial therapy for non-typhoid Salmonella bacteremia in healthy childrenMeng-Hsin Yen
Department of Pediatric Infectious Disease, Chang Gung Children's Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 35:94-8. 2002....
Hemolytic uremic syndrome associated with pneumococcal pneumonia in TaiwanYu-Hsuan Huang
Division of Pediatric Pulmonology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, College of Medicine, 5, Fu Hsin Street, Taoyuan, Taiwan
Eur J Pediatr 165:332-5. 2006..The long-term prognosis for recovery of renal function appears to be good in these patients in northern Taiwan...
A multiplex polymerase chain reaction method for rapid identification of Citrobacter freundii and Salmonella species, including Salmonella TyphiChia Ling Lin
Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
J Microbiol Immunol Infect 40:222-6. 2007..We devised a polymerase chain reaction (PCR) method that simultaneously uses three pairs of specific primers to detect inv, spv, and via genes of Salmonella...
Complication rates with central venous catheters inserted at femoral and non-femoral sites in very low birth weight infantsMing Horng Tsai
Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Children s Hospital, and College of Medicine, Chang Gung University, Taoyuan, Taiwan
Pediatr Infect Dis J 28:966-70. 2009..To compare the complication rates of femoral versus nonfemoral sites of percutaneously inserted central venous catheters (PICCs) in very low birth weight infants...
Survey of the status of self-paid varicella vaccination among children one to six years of age in TaiwanSui Ling Liao
Department of Pediatrics, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Taoyuan, Taiwan
J Microbiol Immunol Infect 40:112-5. 2007..Prior to 2004, the mass immunization program in Taiwan did not include varicella vaccine; however, parents could have their children vaccinated by the self-payment option...
Pneumococcal meningitis in Taiwanese children: emphasis on clinical outcomes and prognostic factorsMing Han Tsai
Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan
J Trop Pediatr 54:390-4. 2008..013) and protein level >or=330 g l(-1) (p = 0.022) were significantly risk factors associated with poor outcomes, and physicians should be cautious if such conditions occur...
Bordetella pertussis infection in northern Taiwan, 1997-2001Pen-Yi Lin
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 37:288-94. 2004..The importance of vaccination still cannot be overemphasized because immunized patients usually present with milder disease than those who are not immunized...
Prognostic implications of myoclonic jerk in children with enterovirus infectionHsiao-Kuo Lu
Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 37:82-7. 2004..95 and 0.99, respectively. This study demonstrated that myoclonic jerk and EV71 infection are both independently associated with more severe disease and higher incidence of neurologic sequelae...
Molecular evidence of congenital candidiasis associated with maternal candidal vaginitisChih-Jung Chen
Division of Pediatric Infectious Diseases, Chang Gung Children's Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 25:655-6. 2006....
Acute hematogenous osteomyelitis and septic arthritis in childrenHui-Chin Kao
Department of Pediatrics, Li-Shin Hospital, Taiwan, ROC
J Microbiol Immunol Infect 36:260-5. 2003..aureus as a cause of bone and joint infections has been increasing. Serum bactericidal titer is valuable for the management of patients receiving sequential therapy for acute hematogenous osteomyelitis and septic arthritis...
Echo-guided management of complicated parapneumonic effusion in childrenChih-Yung Chiu
Division of Pediatric Pulmonology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
Pediatr Pulmonol 41:1226-32. 2006..In children with a fibrin septated parapneumonic effusion, an initial VATS is recommended to shorten the duration of fever and hospital stay...
Fatal bacteremic pneumonia caused by Aeromonas hydrophila in a previously healthy childHsiu-Tsun Kao
Division of Pediatric Infectious Diseases, Chang-Gung Children's Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 36:209-11. 2003..hydrophila infection, though rare, should be considered. More reported cases are needed to establish the epidemiologic features of this disease in children...
Multidrug-resistant non-typhoid Salmonella infections in a medical centerChien-Yu Lee
Department of Pediatrics, Provincial Tao-Yuan Hospital, Taiwan, ROC
J Microbiol Immunol Infect 35:78-84. 2002..choleraesuis found in this study indicate the importance of judicious use of antimicrobial agents in both humans and animals to reduce the selection and spread of resistant strains...
Severe adenovirus infection in childrenY u-Y u Chuang
Department of Pediatrics, St. Mary's Hospital, Taiwan, ROC
J Microbiol Immunol Infect 36:37-40. 2003..Rapid progression of the clinical course despite antibiotic therapy and the presence of unusual extrapulmonary symptoms are important clinical clues in the diagnosis of severe adenoviral infection...
Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous systemTzou-Yien Lin
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan, Republic of China
Clin Infect Dis 36:269-74. 2003..Our findings suggest that the combination of CNS and systemic inflammatory response may trigger EV71-related cardiopulmonary collapse...
Clinical characteristics of children with influenza A virus infection requiring hospitalizationYing-Hsiang Wang
Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 36:111-6. 2003....
Comparative proteomic studies of plasma from children with pneumococcal pneumoniaMing Han Tsai
Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan
Scand J Infect Dis 41:416-24. 2009..Thus, our data seem to indicate that inflammation balance may take place in the occurrence of complicated pneumococcal pneumonia...
Cryptococcosis in nonhuman immunodeficiency virus-infected childrenKuan Ying Huang
Division of Pediatric Infectious Diseases, Chang Gung University, Kweishan, Taoyuan, Taiwan
Pediatr Neurol 42:267-70. 2010..Indian ink stain and cryptococcal antigen testing of cerebrospinal fluid should be performed...
Kawasaki disease in infants three months of age or youngerChih-Hsien Chuang
Department of Pediatrics, Chang Gung Children's Hospital, Kweishan, Taoyuan, Taiwan
J Microbiol Immunol Infect 39:387-91. 2006..A high proportion of coronary artery involvement was observed in this series. Echocardiography should be considered in very young infants with unexplained prolonged fever who do not present all of the principal clinical features of KD...
Neurologic manifestations in children with influenza B virus infectionChien-Hui Lin
Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan
Pediatr Infect Dis J 25:1081-3. 2006..Without appropriate antiviral therapy, recovery was uneventful in all but 1 patient, who had neurologic sequelae of quadriplegia and developmental delay...
Complications of varicella requiring hospitalisation before and after the introduction of varicella vaccine in a children's hospital in TaiwanYu-Yu Chuang
Division of Paediatric Infectious Diseases, Chang Gung Children's Hospital, 5 Fu-Shin Street, Kweishan, Taoyuan, Taiwan
Eur J Pediatr 162:112-3. 2003
Intratypic recombination among lineages of type 1 vaccine-derived poliovirus emerging during chronic infection of an immunodeficient patientChen-Fu Yang
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 79:12623-34. 2005..The appearance of a chronic VDPV excretor in a tropical, developing country has important implications for the strategy to stop OPV immunization after eradication of wild polioviruses...
Candida parapsilosis fungemia in neonates: genotyping results suggest healthcare workers hands as source, and review of published studiesEveline C van Asbeck
Division of Infectious Diseases, Santa Clara Valley Medical Center, California Institute for Medical Research, 751 South Bascom Avenue, San Jose, CA 95128, USA
Mycopathologia 164:287-93. 2007..These findings reinforce prior studies that have implicated HCW hands as the source of nosocomial, including neonatal, fungemia...
