P Ringwald

Summary

Affiliation: World Health Organization
Country: Switzerland

Publications

  1. ncbi Chemoresistance of P. falciparum in urban areas of Yaounde, Cameroon. Part 1: Surveillance of in vitro and in vivo resistance of Plasmodium falciparum to chloroquine from 1994 to 1999 in Yaounde, Cameroon
    P Ringwald
    Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroun
    Trop Med Int Health 5:612-9. 2000
  2. ncbi Chloroquine resistance in Plasmodium falciparum and polymorphism of the CG2 gene
    L K Basco
    Institut de Recherche pour le Developpement, Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la Lutte Contre les Endemies en Afrique Centrale, Yaounde, Cameroon
    J Infect Dis 180:1979-86. 1999
  3. ncbi Chemoresistance of Plasmodium falciparum in the urban region of Yaounde, Cameroon. Part 2: Evaluation of the efficacy of amodiaquine and sulfadoxine-pyrimethamine combination in the treatment of uncomplicated Plasmodium falciparum malaria in Yaounde, Came
    P Ringwald
    Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroun
    Trop Med Int Health 5:620-7. 2000
  4. ncbi Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaoundé, Cameroon
    P Ringwald
    Institut Francais de Recherche Scientifique pour le Developpement en Cooperation ORSTOM, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Bull World Health Organ 77:34-43. 1999
  5. ncbi In vitro activities of pyronaridine, alone and in combination with other antimalarial drugs, against Plasmodium falciparum
    P Ringwald
    Institut de Recherche pour le Développement Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Antimicrob Agents Chemother 43:1525-7. 1999
  6. ncbi Point mutations in the Plasmodium falciparum cg2 gene, polymorphism of the kappa repeat region, and their relationship with chloroquine resistance
    L K Basco
    Institut de recherche pour le developpement IRD, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Trans R Soc Trop Med Hyg 95:309-14. 2001
  7. ncbi In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae)
    J Bickii
    Institut de Recherche pour le Développement ORSTOM and Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la Lutte Contre les Endemies en Afrique Centrale, Yaounde, Cameroon
    J Ethnopharmacol 69:27-33. 2000

Collaborators

Detail Information

Publications7

  1. ncbi Chemoresistance of P. falciparum in urban areas of Yaounde, Cameroon. Part 1: Surveillance of in vitro and in vivo resistance of Plasmodium falciparum to chloroquine from 1994 to 1999 in Yaounde, Cameroon
    P Ringwald
    Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroun
    Trop Med Int Health 5:612-9. 2000
    ..Our results confirm the high level of chloroquine resistance in Yaoundé and suggest that the use of an alternative antimalarial drug for the first-line treatment of uncomplicated malaria is warranted...
  2. ncbi Chloroquine resistance in Plasmodium falciparum and polymorphism of the CG2 gene
    L K Basco
    Institut de Recherche pour le Developpement, Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la Lutte Contre les Endemies en Afrique Centrale, Yaounde, Cameroon
    J Infect Dis 180:1979-86. 1999
    ..These results suggest a strong association between the drug-resistant and CG2 genotypes and support the hypothesis that the CG2 gene may be implicated in chloroquine resistance...
  3. ncbi Chemoresistance of Plasmodium falciparum in the urban region of Yaounde, Cameroon. Part 2: Evaluation of the efficacy of amodiaquine and sulfadoxine-pyrimethamine combination in the treatment of uncomplicated Plasmodium falciparum malaria in Yaounde, Came
    P Ringwald
    Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroun
    Trop Med Int Health 5:620-7. 2000
    ..Amodiaquine has several advantages over sulfadoxine-pyrimethamine combination and may be considered to be an effective drug in an endemic zone with a moderate level of chloroquine resistance...
  4. ncbi Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaoundé, Cameroon
    P Ringwald
    Institut Francais de Recherche Scientifique pour le Developpement en Cooperation ORSTOM, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Bull World Health Organ 77:34-43. 1999
    ....
  5. ncbi In vitro activities of pyronaridine, alone and in combination with other antimalarial drugs, against Plasmodium falciparum
    P Ringwald
    Institut de Recherche pour le Développement Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Antimicrob Agents Chemother 43:1525-7. 1999
    ..Drug combination studies showed synergy between pyronaridine and primaquine, additive effects with 4-aminoquinolines, and weak antagonism with dihydroartemisinin, antifolates, or amino alcohols...
  6. ncbi Point mutations in the Plasmodium falciparum cg2 gene, polymorphism of the kappa repeat region, and their relationship with chloroquine resistance
    L K Basco
    Institut de recherche pour le developpement IRD, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale OCEAC, Yaounde, Cameroon
    Trans R Soc Trop Med Hyg 95:309-14. 2001
    ..The kappa repeat region of the clinical isolates is polymorphic but characterized by several conserved features...
  7. ncbi In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae)
    J Bickii
    Institut de Recherche pour le Développement ORSTOM and Laboratoire de Recherche sur le Paludisme, Laboratoire Associé Francophone 302, Organisation de Coordination pour la Lutte Contre les Endemies en Afrique Centrale, Yaounde, Cameroon
    J Ethnopharmacol 69:27-33. 2000
    ..Five limonoids (1, 3, 5, 6, 8) were active with IC50 values between 1.25 and 9.63 microg/ml. Catechin was practically devoid of activity. The most active limonoid, gedunin, exhibited an additive effect when combined with chloroquine...