Research Topics
Species | P WiesliSummaryAffiliation: University Hospital Country: Switzerland Publications
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Publications
[Hypothyroidism and endocrine orbitopathy]P Wiesli
Departement Innere Medizin, Universitatsspital Zurich
Praxis (Bern 1994) 89:1612-5. 2000..The primary manifestation of Graves' disease with hypothyroidism was caused by blocking TSH receptor antibodies. Chronic autoimmune thyroiditis, Graves' disease and the importance of thyroid autoantibodies are discussed...
Islets secretory capacity determines glucose homoeostasis in the face of insulin resistancePeter Wiesli
Department of Internal Medicine, University Hospital of Zurich, Switzerland
Swiss Med Wkly 134:559-64. 2004..We therefore defined insulin secretion and sensitivity in patients with impaired glucose homoeostasis of varying aetiology and duration...
Abnormalities of proinsulin processing in functioning insulinomas: clinical implicationsPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, Institute for Diagnostic Radiology, University Hospital of Zurich, Switzerland
Clin Endocrinol (Oxf) 61:424-30. 2004..The aim of this study was to test whether such abnormalities in the proinsulin to insulin conversion have clinical implications in patients with hypoglycaemic disorders...
Insulin determination by specific and unspecific immunoassays in patients with insulinoma evaluated by the arterial stimulation and venous sampling testPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, Institute for Diagnostic Radiology, University Hospital of Zurich, CH 8091 Zurich, Switzerland
Eur J Endocrinol 151:123-6. 2004....
Assessment of hyperinsulinaemia at the termination of the prolonged fastPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, CH 8091, Zurich, Switzerland
Clin Chim Acta 342:227-31. 2004..This study was performed to test whether these traditional criteria can be applied when insulin is measured by specific immunoassays...
Serum cystatin C is sensitive to small changes in thyroid functionPeter Wiesli
Department of Internal Medicine, University Hospital of Zurich, CH 8091 Zurich, Switzerland
Clin Chim Acta 338:87-90. 2003..Serum cystatin C (CysC) is a novel marker for kidney function. The impact of mild thyroid dysfunction on CysC has never been investigated...
Extensive spherical amyloid deposition presenting as a pituitary tumorP Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetology, University Hospital of Zurich, Switzerland
J Endocrinol Invest 26:552-5. 2003..Trans-sphenoidal surgical resection is essential to confirm the diagnosis histologically and because of the potential lack of tumor shrinkage under dopaminagonist therapy in this type of prolactinoma...
Mini-Mental State Examination is superior to plasma glucose concentrations in monitoring patients with suspected hypoglycaemic disorders during the 72-hour fastPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, Zurich, Switzerland
Eur J Endocrinol 152:605-10. 2005....
A plasma glucose concentration below 2.5 mmol L-1 is not an appropriate criterion to end the 72-h fastP Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, CH 8091 Zurich, Switzerland
J Intern Med 252:504-9. 2002..However, neither the symptoms nor the plasma glucose level have been exactly defined...
Glucose-induced hypoglycaemiaP Wiesli
Division of Endocrinology and Diabetes, University Hospital of Zurich, CH-8091, Zurich, Switzerland
Lancet 360:1476. 2002
[General insulin therapy practice in type 2 diabetes mellitus]P Wiesli
Abteilung Endokrinologie und Diabetologie, Departement Innere Medizin, Universitatsspital Zurich, Zurich
Ther Umsch 59:402-9. 2002..The two-insulin-injection should not be considered as the primary insulin strategy in patients with Type 2 Diabetes...
[Hyper- and hypothyroidism: which tests are reliable in general practice?]P Wiesli
Departement Innere Medizin, Abteilung Endokrinologie und Diabetologie, Universitatsspital Zurich
Praxis (Bern 1994) 90:877-81. 2001..Additional investigations are usually unnecessary. The indications to perform a thyroid radionuclide scan, thyroid ultrasonography and the determination of thyroid antibodies in patients with primary hyperthyroidism are discussed...
Hypoglycemia in response to glucose and glucagon in insulinoma patients with a negative prolonged fast: functional and morphological propertiesP Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, Institute for Diagnostic Radiology, University Hospital of Zurich, Zurich, Switzerland
J Endocrinol Invest 27:832-8. 2004..Different functional characteristics of these tumors can be correlated with distinct morphological properties...
Assessment of basal insulin requirement using fasting tests in insulin-treated patients with type 2 diabetes mellitusP Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, Zurich, Switzerland
Exp Clin Endocrinol Diabetes 114:539-43. 2006..Characterizing the time course of the rise of blood glucose concentrations in the fasting state during the day and night in patients with type 2 diabetes...
Skipping meals or carbohydrate-free meals in order to determine Basal insulin requirements in subjects with type 1 diabetes mellitus?H Uthoff
Department of Internal Medicine, Endocrinology and Diabetes, Kantonsspital Frauenfeld, Frauenfeld, Switzerland
Exp Clin Endocrinol Diabetes 118:325-7. 2010..e. by skipping meals. The present study examined whether fasting tests could be replaced by carbohydrate-free meals...
Selective arterial calcium stimulation and hepatic venous sampling in the evaluation of hyperinsulinemic hypoglycemia: potential and limitationsPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, Switzerland
J Vasc Interv Radiol 15:1251-6. 2004..To describe the potential and limitations of selective arterial calcium stimulation and hepatic venous sampling (ASVS) in the evaluation of patients with hyperinsulinemic hypoglycemia...
Effect of psychological stress on glucose control in patients with Type 2 diabetesM Faulenbach
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, Zurich, Switzerland
Diabet Med 29:128-31. 2012..To investigate the effect of acute psychological stress on glucose concentrations in patients with Type 2 diabetes, in the fasting state as well as in the postprandial state...
Carcinoid syndrome, acromegaly, and hypoglycemia due to an insulin-secreting neuroendocrine tumor of the liverJ Furrer
Department of Internal Medicine, Medical Policlinic, University Hospital of Zurich, Switzerland
J Clin Endocrinol Metab 86:2227-30. 2001..The patient died 8 yr after the initial diagnosis of the tumor, and a carefully performed autopsy procedure confirmed the absence of any extrahepatic tumor manifestation...
TNF-alpha -308G>A polymorphism modulates cytokine serum concentrations and macrovascular complications in diabetic patients on aspirinP A Krayenbuehl
Department of Internal Medicine, Medical Policlinic, University Hospital of Zurich, Zurich, Switzerland
Exp Clin Endocrinol Diabetes 115:322-6. 2007..Previous studies in non-diabetic subjects showed no association between TNF-alpha -308G>A polymorphism and coronary artery disease...
Insulin sensitivity in type 2 diabetes is closely associated with LDL particle sizePierre A Krayenbuehl
Department of Internal Medicine, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
Swiss Med Wkly 138:275-80. 2008..Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides...
Effect of pituitary surgery in patients with acromegaly on adiponectin serum concentrations and alanine aminotransferase activityPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, CH 8091 Zurich, Switzerland
Clin Chim Acta 352:175-81. 2005..This study was performed to test the effect of neurosurgery in acromegaly (sharing at baseline insulin resistance but not increased visceral fat with type 2 diabetes) on insulin sensitivity, adiponectin concentrations and ALT activity...
Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarismChristoph Schmid
Department of Internal Medicine, Division of Endocrinology and Diabetes, , Switzerland
Clin Endocrinol (Oxf) 65:706-11. 2006....
Impact of thyroid dysfunction on serum cystatin CManuel Fricker
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, Switzerland
Kidney Int 63:1944-7. 2003..In contrast to creatinine concentrations, CysC levels are lower in the hypothyroid and higher in the hyperthyroid state as compared with the euthyroid state...
Acute psychological stress affects glucose concentrations in patients with type 1 diabetes following food intake but not in the fasting statePeter Wiesli
Department of Internal Medicine, Division of EndocrinologyDiabetes, University Hospital of Zurich, CH 8091 Zurich, Switzerland
Diabetes Care 28:1910-5. 2005..To compare the effect of acute psychosocial stress on glucose concentrations in the fasting state and following food intake in patients with type 1 diabetes...
Pancreatic endocrine tumors are a rare manifestation of the neurofibromatosis type 1 phenotype: molecular analysis of a malignant insulinoma in a NF-1 patientAurel Perren
Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland
Am J Surg Pathol 30:1047-51. 2006..Furthermore, the NF1 gene must be considered as a candidate tumor suppressor gene for sporadic insulinomas and probably other pancreatic endocrine tumors...
Recurrent hypoglycaemia in HIV-positive narcotic addictsPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, Switzerland
Swiss Med Wkly 136:805-10. 2006..We describe two narcotic addict women with recurrent hypoglycaemic episodes. In both patients, hyperinsulinaemic hypoglycaemia occurring in the fasting state was documented and computed tomography of the pancreas was normal...
Coincidence of Behçet's disease and SAPHO syndromeM Caravatti
University Hospital Zurich, Zurich, Switzerland
Clin Rheumatol 21:324-7. 2002..These findings resulted in an additional diagnosis of SAPHO syndrome. This report is the first description of Behçet's disease occurring in association with SAPHO syndrome, both fulfilling the diagnostic criteria...
Maintenance of glucose control in patients with type 1 diabetes during acute mental stress by riding high-speed rollercoastersPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, Switzerland
Diabetes Care 30:1599-601. 2007
Pregnancy-induced changes in insulin-like growth factor I (IGF-I), insulin-like growth factor binding protein 3 (IGFBP-3), and acid-labile subunit (ALS) in patients with growth hormone (GH) deficiency and excessPeter Wiesli
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, CH 8091, Switzerland
Acta Obstet Gynecol Scand 85:900-5. 2006..The aim of the present study was to compare the effects of pregnancy in a hypopituitary patient with those of pregnancy in an acromegalic patient on IGF-I, IGFBP-3, and ALS...
Growth hormone (GH) receptor isoform in acromegaly: lower concentrations of GH but not insulin-like growth factor-1 in patients with a genomic deletion of exon 3 in the GH receptor geneChristoph Schmid
University Hospital of Zurich, Department of Internal Medicine, Division of Endocrinology and Diabetes, Zurich, Switzerland
Clin Chem 53:1484-8. 2007..The aim of this study was to test whether the relationship between GH and insulin-like growth factor-1 (IGF-1) concentrations is influenced by the GHR genotype in patients with acromegaly...
Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levelsChristoph Schmid
Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital of Zurich, CH-8091 Zurich, Switzerland
Growth Horm IGF Res 15:300-3. 2005..These data suggest that changes in insulin sensitivity (induced by high dose and short-term GH and IGF-I treatment) in patients with GHD are not associated with changes in adiponectin levels...
Decrease in sE-selectin after pituitary surgery in patients with acromegalyChristoph Schmid
Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital of Zurich, Zurich, Switzerland
Clin Chem 50:650-2. 2004
Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertensionAndreas J Flammer
Cardiovascular Center, Cardiology, University Hospital Zurich, Switzerland
J Hypertens 25:785-91. 2007..We investigated the influence of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension...
Chlamydia pneumoniae, harmful only for peripheral arteries?Georg Schulthess
Int J Cardiol 112:249-50. 2006
