A Schnider

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi What does recovery from anomia tell us about the underlying impairment: the case of similar anomic patterns and different recovery
    Marina Laganaro
    Service de Rééducation, Neuropsychologie, Hopitaux Universitaires de Geneve, Av Beau Séjour 26, CH 1211 Geneva 14, Switzerland
    Neuropsychologia 44:534-45. 2006
  2. ncbi Reality confusion in spontaneous confabulation
    Armin Schnider
    Division of Rehabilitation, Department of Clinical Neurosciences, University Hospital, Geneva, Switzerland
    Neurology 65:1117-9. 2005
  3. ncbi Selection of currently relevant words: an auditory verbal memory study using positron emission tomography
    Valerie Treyer
    PET Center, Division of Nuclear Medicine, University Hospital, Zurich, Switzerland
    Neuroreport 17:323-7. 2006
  4. ncbi Cortical and subcortical anatomy of chronic spatial neglect following vascular damage
    Laetitia Golay
    Division of Neurorehabilitation, Geneva University Hospitals and University of Geneva, 1211 Geneva 14, Switzerland
    Behav Brain Funct 4:43. 2008
  5. ncbi Spontaneous confabulation and the adaptation of thought to ongoing reality
    Armin Schnider
    , , , CH-1211 Geneva 14, Switzerland
    Nat Rev Neurosci 4:662-71. 2003
  6. ncbi Early cortical response to behaviorally relevant absence of anticipated outcomes: a human event-related potential study
    Armin Schnider
    Laboratory of Cognitive Neurorehabilitation, Division of Neurorehabilitation, University Hospital Geneva, Av de Beau Séjour 26, CH 1211 Geneva 14, Switzerland
    Neuroimage 35:1348-55. 2007
  7. ncbi Absence of visual feedback abolishes expression of hemispatial neglect in self-guided spatial completion
    Armin Schnider
    Division of Neurorehabilitation, University Hospitals of Geneva, 26, Av de Beau Séjour, CH 1211 Geneva 14, Switzerland
    J Neurol Neurosurg Psychiatry 82:1279-82. 2011
  8. ncbi Early cortical distinction between memories that pertain to ongoing reality and memories that don't
    Armin Schnider
    Rehabilitation Clinic, Neurology Clinic, University Hospital, Geneva, Switzerland
    Cereb Cortex 12:54-61. 2002
  9. ncbi Spontaneous confabulation, reality monitoring, and the limbic system--a review
    A Schnider
    Department of Rehabilitation, University Hospital, Av de Beau Séjour 26, CH 1211 14, Geneva, Switzerland
    Brain Res Brain Res Rev 36:150-60. 2001
  10. ncbi The human orbitofrontal cortex monitors outcomes even when no reward is at stake
    Armin Schnider
    Department of Rehabilitation, University Hospital, CH 1211 Geneva 14, Switzerland
    Neuropsychologia 43:316-23. 2005

Collaborators

Detail Information

Publications60

  1. ncbi What does recovery from anomia tell us about the underlying impairment: the case of similar anomic patterns and different recovery
    Marina Laganaro
    Service de Rééducation, Neuropsychologie, Hopitaux Universitaires de Geneve, Av Beau Séjour 26, CH 1211 Geneva 14, Switzerland
    Neuropsychologia 44:534-45. 2006
    ....
  2. ncbi Reality confusion in spontaneous confabulation
    Armin Schnider
    Division of Rehabilitation, Department of Clinical Neurosciences, University Hospital, Geneva, Switzerland
    Neurology 65:1117-9. 2005
    ..The findings support the theory that the defect causing spontaneous confabulation precedes conscious memory processing...
  3. ncbi Selection of currently relevant words: an auditory verbal memory study using positron emission tomography
    Valerie Treyer
    PET Center, Division of Nuclear Medicine, University Hospital, Zurich, Switzerland
    Neuroreport 17:323-7. 2006
    ..In this H2O positron emission tomography study, we demonstrate that this same organizing principle also applies to auditory verbal information, that is, to the processing of auditorily presented words...
  4. ncbi Cortical and subcortical anatomy of chronic spatial neglect following vascular damage
    Laetitia Golay
    Division of Neurorehabilitation, Geneva University Hospitals and University of Geneva, 1211 Geneva 14, Switzerland
    Behav Brain Funct 4:43. 2008
    ..abstract:..
  5. ncbi Spontaneous confabulation and the adaptation of thought to ongoing reality
    Armin Schnider
    , , , CH-1211 Geneva 14, Switzerland
    Nat Rev Neurosci 4:662-71. 2003
  6. ncbi Early cortical response to behaviorally relevant absence of anticipated outcomes: a human event-related potential study
    Armin Schnider
    Laboratory of Cognitive Neurorehabilitation, Division of Neurorehabilitation, University Hospital Geneva, Av de Beau Séjour 26, CH 1211 Geneva 14, Switzerland
    Neuroimage 35:1348-55. 2007
    ..The study indicates early, specific cortical processing of behaviorally relevant absence of predicted outcomes...
  7. ncbi Absence of visual feedback abolishes expression of hemispatial neglect in self-guided spatial completion
    Armin Schnider
    Division of Neurorehabilitation, University Hospitals of Geneva, 26, Av de Beau Séjour, CH 1211 Geneva 14, Switzerland
    J Neurol Neurosurg Psychiatry 82:1279-82. 2011
    ..Patients with left neglect direct their attention too strongly to the right. Hypotheses hold that this is due to a failure to disengage attention from right-sided stimuli or to a directional bias of attention into right space...
  8. ncbi Early cortical distinction between memories that pertain to ongoing reality and memories that don't
    Armin Schnider
    Rehabilitation Clinic, Neurology Clinic, University Hospital, Geneva, Switzerland
    Cereb Cortex 12:54-61. 2002
    ..This sequence may also explain the ability to distinguish between the memory of a true event and the memory of a thought...
  9. ncbi Spontaneous confabulation, reality monitoring, and the limbic system--a review
    A Schnider
    Department of Rehabilitation, University Hospital, Av de Beau Séjour 26, CH 1211 14, Geneva, Switzerland
    Brain Res Brain Res Rev 36:150-60. 2001
    ..Comparison with animal studies suggests that human reality monitoring is a property of the brain's reward system...
  10. ncbi The human orbitofrontal cortex monitors outcomes even when no reward is at stake
    Armin Schnider
    Department of Rehabilitation, University Hospital, CH 1211 Geneva 14, Switzerland
    Neuropsychologia 43:316-23. 2005
    ..The data indicate a generic role of the human OFC, with some topical specificity, in the generation of hypotheses and processing of outcomes, independent of the presence of explicit reward...
  11. ncbi Dopaminergic modulation of rapid reality adaptation in thinking
    A Schnider
    Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospitals and University of Geneva, Geneva, Switzerland
    Neuroscience 167:583-7. 2010
    ..We conclude that dopaminergic transmission influences the ability to rapidly adapt thinking to ongoing reality...
  12. ncbi Selection of currently relevant memories by the human posterior medial orbitofrontal cortex
    A Schnider
    Clinique de Rééducation, University Hospital, Geneva, Switzerland
    J Neurosci 20:5880-4. 2000
    ..We suggest that this area is essential for sorting out mental associations that pertain to ongoing reality...
  13. ncbi Recovery from spontaneous confabulations parallels recovery of temporal confusion in memory
    A Schnider
    Rehabilitation Clinic, University Hospital, Geneva, Switzerland
    Neurology 55:74-83. 2000
    ....
  14. ncbi Spontaneous confabulations, disorientation, and the processing of 'now'
    A Schnider
    University Department of Neurology, Bern, Switzerland
    Neuropsychologia 38:175-85. 2000
    ..Although these results do not prove a causal relationship, they indicate that spontaneously confabulating and disorientated patients typically do fail to process information within the 'now'...
  15. ncbi Spontaneous confabulators fail to suppress currently irrelevant memory traces
    A Schnider
    Department of Neurology, University Hospital, Bern, Switzerland
    Nat Neurosci 2:677-81. 1999
    ..We suggest that the anterior limbic system represents 'now' in human thinking by suppressing currently irrelevant mental associations...
  16. ncbi Probabilistic contingency learning with limbic or prefrontal damage
    R Ptak
    Clinique de Rééducation, Hĵpital Universitaire Genève, Switzerland
    Behav Neurosci 115:993-1001. 2001
    ..These results indicate that probabilistic learning does not depend on the brain structures supporting declarative memory...
  17. ncbi Instinctive modulation of cognitive behavior: a human evoked potential study
    Louis Nahum
    Department of Clinical Neurosciences, Division of Neurorehabilitation, University Hospitals and University of Geneva, Switzerland
    Hum Brain Mapp 30:2120-31. 2009
    ..The study indicates rapid serial processing of innate emotional quality, then cognitive-behavioral relevance of stimuli, mediated by limbic and paralimbic structures...
  18. ncbi Effects of baseline task position on apparent activation in functional imaging of memory
    Valerie Treyer
    PET Center, Division of Nuclear Medicine, University Hospital, , Switzerland
    Neuropsychologia 44:462-8. 2006
    ..We suggest that the automatic filtration of memories according to their relevance for ongoing reality, a capacity mediated by the orbitofrontal cortex, is one such influence on apparent activation...
  19. ncbi Rapid discrimination of visual and multisensory memories revealed by electrical neuroimaging
    Micah M Murray
    The Functional Brain Mapping Laboratory, Neurology Clinic, University Hospital of Geneva, 1211, Geneva, Switzerland
    Neuroimage 21:125-35. 2004
    ....
  20. ncbi Disorientation, confabulation, and extinction capacity: clues on how the brain creates reality
    Louis Nahum
    Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospital and University of Geneva, CH 1211 Geneva 14, Switzerland
    Biol Psychiatry 65:966-72. 2009
    ..In this study, we explored whether disorientation and behaviorally spontaneous confabulation are associated with extinction failure...
  21. ncbi Electrophysiological correlates of different anomic patterns in comparison with normal word production
    Marina Laganaro
    Division of Neurorehabilitation, Geneva Hospital and University of Geneva, Geneva, Switzerland
    Cortex 45:697-707. 2009
    ..These results indicate that abnormal electro-cortical correlates of anomic profiles can be observed in different time-windows, which seem to correspond to the time course of the impaired encoding processes...
  22. ncbi Neural transition from short- to long-term memory and the medial temporal lobe: a human evoked-potential study
    Clara James
    Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospital and University of Geneva, Geneva, Switzerland
    Hippocampus 19:371-8. 2009
    ..Processing of novel information seems to immediately initiate a consolidation process, which remains vulnerable during active maintenance and increases its effectiveness during off-line processing...
  23. ncbi Electrophysiological correlates of deficient encoding in a case of post-anoxic amnesia
    Sandra Lehmann
    Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospital, CH 1211 Geneva 14, Switzerland
    Neuropsychologia 45:1757-66. 2007
    ..The present study suggests that the rapid activation of distributed cortical networks is critical for efficient encoding...
  24. ncbi Receptive amusia: temporal auditory processing deficit in a professional musician following a left temporo-parietal lesion
    Marie Di Pietro
    , , 26, , , Switzerland
    Neuropsychologia 42:868-77. 2004
    ..Rather, our findings suggest modality-specific encoding of musical temporal information. Besides, it is proposed that the processing of auditory rhythmic sequences involves a specific left hemispheric temporal buffer...
  25. ncbi Abnormal cortical network activation in human amnesia: A high-resolution evoked potential study
    Sandra Barcellona-Lehmann
    Department of Clinical Neurosciences, University Hospitals and University of Geneva, Switzerland
    Brain Topogr 23:72-81. 2010
    ..The study indicates that cortical mechanisms underlying memory formation and re-activation in amnesia fundamentally differ from normal memory processing...
  26. ncbi Hypothalamic amnesia with spontaneous confabulations: a clinicopathologic study
    R Ptak
    Department of Rehabilitation, University Hospital, Geneva, Switzerland
    Neurology 56:1597-600. 2001
    ..Isolated hypothalamic damage may produce the same type of memory disorder as orbitofrontal damage...
  27. ncbi [Expansion of the sphere of crisis: the question of the intrusiveness of the disease]
    O Dufour
    Departement de Psychiatrie, HUG, 1211 Geneve 14
    Rev Med Suisse 6:347-52. 2010
    ..This article addresses the high complexity of clinical situations handled in an environment of rehabilitation care with the support of the consultants, nurses and doctors, of the liaison psychiatry...
  28. ncbi [Ischemic, an uncommon complication of Biermer disease (pernicious anemia)]
    B Leemann
    Service de Rééducation, HUG, Switzerland
    Rev Neurol (Paris) 162:1007-10. 2006
    ..Stroke in a young adult justifies an extensive etiologic workup...
  29. ncbi [Functional weakness of movement]
    B Leemann
    Service de neurorééducation, Départment des neurosciences cliniques, HUG, 1211 Geneve 14
    Rev Med Suisse 7:408-11. 2011
    ..The long-term prognosis is bad. The treatment includes cognitive-behavioral therapy and rehabilitation to develop a positive attitude...
  30. ncbi [Constraint-induced movement therapy in neurological rehabilitation: which modality to choose? Our experience in rehabilitation in Geneva]
    B Leemann
    Service de neurorééducation, Hopitaux Universitaires de Geneve, 26, Avenue Beau Sejour, 1211 Geneve 14, Suisse
    Ann Readapt Med Phys 51:31-7. 2008
    ..CIMT consists of restraining the unaffected arm to limit its use, combined with a training program based on the shaping principle. We aimed to explore how this method can be used in practice by studying 4 patients after stroke...
  31. ncbi Expectation-based attentional modulation of visual extinction in spatial neglect
    Radek Ptak
    Clinique de Rééducation, Hopital Cantonal Universitaire, 26, Av de Beau Séjour, CH 1211 14, Geneva, Switzerland
    Neuropsychologia 40:2199-205. 2002
    ..These results suggest that competition for selection between visual stimuli may not only be influenced by perceptual characteristics of the display, but also by high-level factors such as the response criterion or expectation biases...
  32. ncbi Looking left with left neglect: the role of spatial attention when active vision selects local image features for fixation
    Radek Ptak
    Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland Medical School, University of Geneva, Switzerland
    Cortex 45:1156-66. 2009
    ..These results suggest that intact spatial attention is necessary for the active sampling of local feature content during scene perception...
  33. ncbi [Unusually favorable recovery from locked-in syndrome after basilar artery occlusion]
    Beatrice Leemann
    Service de neurorééducation HUG, 1211 Geneve 14
    Rev Med Suisse 6:633-5. 2010
    ..We describe a case with remarkable recovery. After 2 years the patient was independent for daily living activities, walks independently and has comprehensible speech...
  34. ncbi Effect of different walking aids on walking capacity of patients with poststroke hemiparesis
    Lara Allet
    Department of Clinical Neurosciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    Arch Phys Med Rehabil 90:1408-13. 2009
    ..To examine the effects of 3 different walking aids on walking capacity, temporo-spatial gait parameters, and patient satisfaction...
  35. ncbi Bilateral impairment of concurrent saccade programming in hemispatial neglect
    Radek Ptak
    Division of Neurorehabilitation, University Hospital Geneva, 1211 Geneva 14, Switzerland
    Neuropsychologia 48:880-6. 2010
    ..This pattern is consistent with a severe, bilateral impairment of concurrent saccade programming in left spatial neglect...
  36. ncbi Neural response to the behaviorally relevant absence of anticipated outcomes and the presentation of potentially harmful stimuli: A human fMRI study
    Louis Nahum
    Laboratory of Cognitive Neurorehabilitation, Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospitals and University of Geneva, Switzerland
    Cortex 47:191-201. 2011
    ..By contrast, the absence of anticipated outcomes specifically activated the orbitofrontal cortex (OFC), irrespective of the iES of the outcome stimulus. The findings support a generic role of the OFC in outcome monitoring...
  37. ncbi Crossover trial of subacute computerized aphasia therapy for anomia with the addition of either levodopa or placebo
    Beatrice Leemann
    Service de neurorééducation, University Hospital of Geneva, Geneva, Switzerland
    Neurorehabil Neural Repair 25:43-7. 2011
    ..The effect of levodopa on recovery from aphasia is controversial...
  38. ncbi The dorsal attention network mediates orienting toward behaviorally relevant stimuli in spatial neglect
    Radek Ptak
    Division of Neurorehabilitation, Geneva University Hospitals, and Faculty of Medicine, University of Geneva, 1211 Geneva 14, Switzerland
    J Neurosci 30:12557-65. 2010
    ..These findings indicate that the dorsal attention network controls spatial orienting by modulating the saliency of distracter stimuli according to current action goals...
  39. ncbi Early event-related cortical activity originating in the frontal eye fields and inferior parietal lobe predicts the occurrence of correct and error saccades
    Radek Ptak
    Division of Neurorehabilitation, Geneva University Hospitals, Geneva, Switzerland
    Hum Brain Mapp 32:358-69. 2011
    ..These findings suggest that selection of the saccade target in a conflicting situation is determined by early top-down biases originating in frontal and parietal cortical regions critical for spatial attention and saccade programming...
  40. ncbi Dopamine inhibition and the adaptation of behavior to ongoing reality
    Hans Pihan
    Department of Neurology, Division of Neuropsychological Rehabilitation, University Hospital, Bern, Switzerland
    Neuroreport 15:709-12. 2004
    ..We present a patient who regained the ability to adapt thought and behavior to ongoing reality when treated with risperidone, a dopamine antagonist...
  41. ncbi Disorganised memory after right dorsolateral prefrontal damage
    Radek Ptak
    Service de Rééducation, HUG, Geneve, Switzerland
    Neurocase 10:52-9. 2004
    ..This case exemplifies that an isolated lesion of the right area 9/46 may induce severe failure to schedule actions and memory retrieval, a disorder leading to severely disorganised behaviour and disability...
  42. ncbi Reflexive orienting in spatial neglect is biased towards behaviourally salient stimuli
    Radek Ptak
    Division of Rehabilitation, University Hospital Geneva, 26 avenue de Beau Séjour, CH 1211 Geneva 14, Switzerland
    Cereb Cortex 16:337-45. 2006
    ..These results show that neglect patients only orient attention reflexively towards ipsilesional stimuli with high behavioural salience...
  43. ncbi Dynamic modulation of visual detection by auditory cues in spatial neglect
    Laetitia Golay
    Service de Rééducation, HUG, 26 av de Beau Séjour, 1211 Geneve 14, Switzerland
    Neuropsychologia 43:1258-65. 2005
    ..These results demonstrate a fast automatic shift of spatial attention in the direction of a moving tone, suggesting strong dynamic links between visual and auditory attention in patients with a severe spatial deficit...
  44. ncbi Computerised treatment of anomia in acute aphasia: treatment intensity and training size
    Marina Laganaro
    Service de Rééducation, University Hospital, Geneva, Switzerland
    Neuropsychol Rehabil 16:630-40. 2006
    ..The integration of these results within the framework of studies on intensity is discussed...
  45. ncbi A non-spatial bias favouring fixated stimuli revealed in patients with spatial neglect
    Radek Ptak
    Division of Neurorehabilitation, University Hospital Geneva, 1211 Geneva 14, Switzerland
    Brain 130:3211-22. 2007
    ..We conclude that impaired initiation of saccades in any direction contributes to the deficits of spatial exploration that characterize spatial neglect...
  46. ncbi Normalisation and increase of abnormal ERP patterns accompany recovery from aphasia in the post-acute stage
    Marina Laganaro
    Laboratory of Cognitive Rehabilitation, Division of Rehabilitation, Geneva University Hospital and University of Geneva, Switzerland
    Neuropsychologia 46:2265-73. 2008
    ....
  47. ncbi Time estimation in Parkinson's disease: normal long duration estimation despite impaired short duration discrimination
    J M Riesen
    University Department of Neurology, Inselspital Bern, and Rehabilitation Clinic University Hospital, Geneva, Switzerland
    J Neurol 248:27-35. 2001
    ..We suggest that time estimation, i. e. the feeling for the flow of time, is normal in PD patients despite impaired discrimination of brief intervals in the range of seconds...
  48. ncbi Peripheral dysgraphia characterized by the co-occurrence of case substitutions in uppercase and letter substitutions in lowercase writing
    M Di Pietro
    Division of Neurorehabilitation, Department of Clinical Neurosciences, University Hospitals and University of Geneva, Switzerland
    Cortex 47:1038-51. 2011
    ....
  49. ncbi Processing content or location: distinct brain activation in a memory task
    Valerie Treyer
    PET Center, Division of Nuclear Medicine, University Hospital, Zurich, Switzerland
    Hippocampus 15:684-9. 2005
    ..These data demonstrate distinct contributions of the left and right MTL to the processing of "what" vs. "where" in memory...
  50. ncbi Mechanism of disorientation in Alzheimer's disease
    Sabine Joray
    Memory Clinic, Department of Geriatrics, Geneva University Hospitals, Geneva, Switzerland
    Eur Neurol 52:193-7. 2004
    ..This finding is compatible with the different distribution of degeneration in AD and the orbitofrontal damage typically present in severely disoriented amnesics...
  51. ncbi Neutral functional realignment orthosis prevents hand pain in patients with subacute stroke: a randomized trial
    Elisabeth Bürge
    Haute école de santé Geneva, HES SO University of Applied Sciences Western Switzerland, Geneva, Switzerland
    Arch Phys Med Rehabil 89:1857-62. 2008
    ..To quantify the preventive effect of a neutral functional realignment orthosis on pain, mobility, and edema of the hand in subacute hemiparetic poststroke patients with severe motor deficits...
  52. ncbi Paradoxical switching to a barely-mastered second language by an aphasic patient
    B Leemann
    Division for Rehabilitation, Geneva University Hospitals, Geneva, Switzerland
    Neurocase 13:209-13. 2007
    ..We concluded, in line with previous reports, that our case used his metalinguistic knowledge to compensate for his inability to access his linguistic skills...
  53. ncbi Masseter muscle thickness in hospitalised stroke patients
    M Schimmel
    Division of Gerodontology and Removable Prosthodontics, University of Geneva, Geneva, Switzerland
    J Oral Rehabil 37:726-30. 2010
    ..This asymmetric stimulation of the masticatory muscles may have caused this difference in the masseter muscle bulk...
  54. ncbi Dissociated active and passive tactile shape recognition: a case study of pure tactile apraxia
    N Valenza
    Clinique de Rééducation, Hopitaux Universitaires de Geneve, Geneve, Switzerland
    Brain 124:2287-98. 2001
    ..We interpret the deficit of our patient as a pure tactile apraxia without tactile agnosia, i.e. a specific inability to use tactile feedback to generate the exploratory procedures necessary for tactile shape recognition...
  55. ncbi Defective spatial imagery with pure Gerstmann's syndrome
    Antonio Carota
    Service de Rééducation, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Eur Neurol 52:1-6. 2004
    ..We hypothesize that, in this case, the main cognitive denominator of Gerstmann's tetrad was a severe dysfunction in mental rotation and translation. This report provides further evidence for the spatial nature of Gerstmann's syndrome...
  56. ncbi Subcortical loop activation during selection of currently relevant memories
    Valerie Treyer
    University Hospital,
    J Cogn Neurosci 15:610-8. 2003
    ..The data are compatible with a role of the dopaminergic reward system in the monitoring of ongoing reality in thinking...
  57. ncbi Functional magnetic resonance imaging and diffusion tensor imaging in a case of central poststroke pain
    Mohamed L Seghier
    Department of Radiology, University of Hospital of Geneva, Switzerland
    J Pain 6:208-12. 2005
    ..Our investigations show, for CPSP pathogenesis, the role of damage of lateral nociceptive thalamoparietal fibers together with the release of activity of anterior cingulate and posterior parietal regions...
  58. ncbi Dramatic recovery from prolonged Wernicke-Korsakoff disease
    Antonio Carota
    , , , Suisse
    Eur Neurol 53:45-6. 2005
  59. ncbi A technique to train new oculomotor behavior in patients with central macular scotomas during reading related tasks using scanning laser ophthalmoscopy: immediate functional benefits and gains retention
    Anouk Déruaz
    Ophthalmology Clinic, Department of Clinical Neurosciences and Dermatology, Geneva University Hospitals, Switzerland
    BMC Ophthalmol 6:35. 2006
    ..We use an additional fixation point which, when combined with the initial PRL, allows the fulfillment of both letter resolution and global viewing of words...