S Schaub

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Prednisone-induced neutropenia after cadaveric kidney transplantation
    Stefan Schaub
    Division of Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Nephrol Dial Transplant 17:1119-21. 2002
  2. ncbi Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients
    Adrian Egli
    Transplantation Virology, Institute for Medical Microbiology, University of Basel, Petersplatz 10, 4003 Basel, Switzerland
    J Transl Med 6:29. 2008
  3. ncbi Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy
    S Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Switzerland
    Am J Transplant 10:2615-23. 2010
  4. ncbi Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology
    Stefan Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 84:104-12. 2007
  5. ncbi Transient allograft dysfunction from immune reconstitution in a patient with polyoma BK-virus-associated nephropathy
    Stefan Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Switzerland
    Nephrol Dial Transplant 22:2386-90. 2007
  6. ncbi Developing a tool for noninvasive monitoring of renal allografts
    Stefan Schaub
    University Hospital Basel, Department for Transplantation Immunology and Nephrology, Petersgraben 4, 4031 Basel, Switzerland
    Expert Rev Proteomics 3:497-509. 2006
  7. ncbi Proteomics and renal transplantation: searching for novel biomarkers and therapeutic targets
    Stefan Schaub
    Department for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Contrib Nephrol 160:65-75. 2008
  8. ncbi Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis
    S Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Am J Transplant 9:1347-53. 2009
  9. ncbi The number of activating KIR genes inversely correlates with the rate of CMV infection/reactivation in kidney transplant recipients
    M Stern
    Clinic for Hematology, Department of Research, University Hospital Basel, Switzerland
    Am J Transplant 8:1312-7. 2008
  10. ncbi Polyomavirus BK-specific cellular immune response to VP1 and large T-antigen in kidney transplant recipients
    S Binggeli
    Transplantation Virology, Institute for Medical Microbiology, University of Basel, Basel, Switzerland
    Am J Transplant 7:1131-9. 2007

Collaborators

Detail Information

Publications29

  1. ncbi Prednisone-induced neutropenia after cadaveric kidney transplantation
    Stefan Schaub
    Division of Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Nephrol Dial Transplant 17:1119-21. 2002
  2. ncbi Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients
    Adrian Egli
    Transplantation Virology, Institute for Medical Microbiology, University of Basel, Petersplatz 10, 4003 Basel, Switzerland
    J Transl Med 6:29. 2008
    ..We hypothesized that low CMV-specific T-cell responses are associated with increased risk of CMV replication in R(+)-patients with D(+) or D(-) donors...
  3. ncbi Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy
    S Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Switzerland
    Am J Transplant 10:2615-23. 2010
    ..6 mg/dl and 1.3 mg/dl, respectively. We conclude that screening for BKV-replication and reduction of immunosuppression is an effective strategy to preserve medium-term allograft function even in patients developing definitive PyVAN...
  4. ncbi Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology
    Stefan Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 84:104-12. 2007
    ..This study investigated whether urinary tubular injury biomarkers can detect subclinical tubulitis found in protocol biopsies allowing for a noninvasive screening procedure...
  5. ncbi Transient allograft dysfunction from immune reconstitution in a patient with polyoma BK-virus-associated nephropathy
    Stefan Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Switzerland
    Nephrol Dial Transplant 22:2386-90. 2007
  6. ncbi Developing a tool for noninvasive monitoring of renal allografts
    Stefan Schaub
    University Hospital Basel, Department for Transplantation Immunology and Nephrology, Petersgraben 4, 4031 Basel, Switzerland
    Expert Rev Proteomics 3:497-509. 2006
    ....
  7. ncbi Proteomics and renal transplantation: searching for novel biomarkers and therapeutic targets
    Stefan Schaub
    Department for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Contrib Nephrol 160:65-75. 2008
    ....
  8. ncbi Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis
    S Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Am J Transplant 9:1347-53. 2009
    ..002), but only tubular injury markers were elevated in IF/TA. These results demonstrate a correlation of urinary CXCL9 and CXCL10 levels with the extent of subclinical tubulitis suggesting potential as noninvasive screening biomarkers...
  9. ncbi The number of activating KIR genes inversely correlates with the rate of CMV infection/reactivation in kidney transplant recipients
    M Stern
    Clinic for Hematology, Department of Research, University Hospital Basel, Switzerland
    Am J Transplant 8:1312-7. 2008
    ..Also, graft function and the rate-rejection episodes were similar in KIR A/A and KIR B/X genotype individuals. This study supports a role for activating KIR in the control of CMV infection after kidney transplantation...
  10. ncbi Polyomavirus BK-specific cellular immune response to VP1 and large T-antigen in kidney transplant recipients
    S Binggeli
    Transplantation Virology, Institute for Medical Microbiology, University of Basel, Basel, Switzerland
    Am J Transplant 7:1131-9. 2007
    ..Stimulation with JCV-specific VP1 and LT peptides indicated only low-level cross-recognition. The data suggest that control of BKV replication is correlated with differentiated expansion of BKV-specific cellular immune responses...
  11. ncbi Efficacy of induction therapy with ATG and intravenous immunoglobulins in patients with low-level donor-specific HLA-antibodies
    K Bächler
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Am J Transplant 10:1254-62. 2010
    ..We conclude that in patients with low-level HLA-DSA, ATG/IvIg induction significantly reduces TCR and the severity of AMR, but the high rate of subclinical AMR suggests an insufficient control of the humoral immune response...
  12. ncbi Pretransplant risk assessment in renal allograft recipients using virtual crossmatching
    D Bielmann
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Am J Transplant 7:626-32. 2007
    ..However, further studies need to address whether all HLA-antibodies detected by flow-beads are clinically relevant...
  13. ncbi Haemolytic uraemic syndrome caused by factor H mutation: is single kidney transplantation under intensive plasmatherapy an option?
    Patricia Hirt-Minkowski
    Division of Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Nephrol Dial Transplant 24:3548-51. 2009
    ..He received peri- and postoperative infusions of fresh frozen plasma, which to date has prevented recurrence of the disease. He has preserved renal function 1-year post-transplant...
  14. ncbi Urinary C4d does not correlate with C4d-staining in peritubular capillaries but reflects nonspecific glomerular injury
    Gideon Hönger
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 85:542-6. 2008
    ..This study investigated whether urinary C4d correlates with C4d-staining in PTC, allowing for a noninvasive screening procedure...
  15. ncbi Fibrillary glomerulonephritis: early diagnosis associated with steroid responsiveness
    Michael Dickenmann
    Division of Transplantation Immunology and Nephrology, Institute for Pathology, University Hospital, Basel, Switzerland
    Am J Kidney Dis 40:E9. 2002
    ..Early start of treatment in patients with preserved renal function seems to be crucial for a favorable outcome...
  16. ncbi Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads
    Patrizia Amico
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 87:1681-8. 2009
    ..The aims of this study were to investigate to which extent HLA-DSA detected by SAFB represent a risk for antibody-mediated rejection (AMR) and diminished allograft survival, and to define HLA-DSA characteristics predictive for AMR...
  17. ncbi Incidence and prediction of early antibody-mediated rejection due to non-human leukocyte antigen-antibodies
    Patrizia Amico
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 85:1557-63. 2008
    ..However, data on the incidence of early AMR due to non-HLA-DSA are currently lacking...
  18. ncbi Intraoperative color duplex ultrasound during renal transplantation
    C Thalhammer
    Angiology, University Hospital, Basel, Switzerland
    Ultraschall Med 29:652-6. 2008
    ..Color duplex ultrasound is a useful procedure in selected conditions with an intraoperatively suspected perfusion problem during renal transplantation...
  19. ncbi C4d-fixing capability of low-level donor-specific HLA antibodies is not predictive for early antibody-mediated rejection
    Gideon Hönger
    Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 89:1471-5. 2010
    ..The aim of this study was to investigate whether the pretransplant C4d-fixing capability allows distinguishing harmful from presumably clinically irrelevant HLA-DSA...
  20. ncbi Utility of the virtual crossmatch in solid organ transplantation
    Patrizia Amico
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Switzerland
    Curr Opin Organ Transplant 14:656-61. 2009
    ..In this review, prospects and current limitation of the virtual crossmatch are discussed...
  21. ncbi Detection of HLA-antibodies prior to renal transplantation: prospects and limitations of new assays
    Patrizia Amico
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Swiss Med Wkly 138:472-6. 2008
    ..In this mini-review we will describe recent advances in the techniques used to detect donor-specific HLA antibodies with emphasis on their potential application for patient management and their current limitations...
  22. ncbi Contribution of early failure to outcome on peritoneal dialysis
    Bernard Descoeudres
    Transplantation Immunology and Nephrology, Basel Institute for Clinical Epidemiology, Basel, Switzerland
    Perit Dial Int 28:259-67. 2008
    ..Aim: To analyze the importance of early treatment failure in PD and to compare early with late failures with respect to reasons and predictors of risk for failure...
  23. ncbi Relapsing severe anaemia due to primary parvovirus B19 infection after renal transplantation: a case report and review of the literature
    Angelika Beckhoff
    Clinic for Transplantation Immunology and Nephrology, Institute for Medical Microbiology, University of Basel, Basel, Switzerland
    Nephrol Dial Transplant 22:3660-3. 2007
  24. ncbi Proteomic-based identification of cleaved urinary beta2-microglobulin as a potential marker for acute tubular injury in renal allografts
    Stefan Schaub
    Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada
    Am J Transplant 5:729-38. 2005
    ..These factors ultimately lead to increased amounts of cleaved urinary beta2-microglobulin. Cleaved beta2-microglobulin as an indicator of acute tubular injury may become a useful tool for noninvasive monitoring of renal allografts...
  25. ncbi Proteomic-based detection of urine proteins associated with acute renal allograft rejection
    Stefan Schaub
    Faculty of Medicine, University of Manitoba, and Manitoba Centre for Proteomics, Winnipeg, Manitoba, Canada
    J Am Soc Nephrol 15:219-27. 2004
    ..Identification of these proteins may prove useful as non-invasive diagnostic markers for rejection and the development of novel therapeutic agents...
  26. ncbi Prevalence, consequences, and determinants of nonadherence in adult renal transplant patients: a literature review
    Kris Denhaerynck
    Institute of Nursing Science, University of Basel, Bernoullistrasse 28, CH-4056 Basel, Switzerland
    Transpl Int 18:1121-33. 2005
    ..Because the evidence summarized in this review is based on older immunosuppressive regimens, further research should focus on prevalence, determinants and consequences of nonadherence with newer immunosuppressive regimens...
  27. ncbi Urine protein profiling with surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry
    Stefan Schaub
    Immunogenetics Laboratory, Faculty of Medicine, Winnipeg, Manitoba, Canada
    Kidney Int 65:323-32. 2004
    ....
  28. ncbi Renal vein thrombosis after renal transplantation--early diagnosis by duplex sonography prevented fatal outcome
    Markus Aschwanden
    Nephrol Dial Transplant 21:825-6. 2006
  29. ncbi Testing the "cytokine-ome" theory: a longitudinal pilot study in renal transplant recipients
    Olivier Gasser
    Transplantation 85:491-2. 2008