Matthias E Pfisterer

..On the basis of the data and considerations presented, a strategy of initial optimum pharmacological therapy or direct invasive management can be tailored to an individual's circumstances and preferences...

..These aspects are summarised in the present review, highlighting lessons learned from each study and commenting on the possibilities and difficulties of performing such clinical research in Switzerland...

..However, physical functioning related to daily activities is reduced in those with DM and may need special attention...

..Drug-eluting stents (DESs) are associated with late stent thromboses, but the exact mechanism of action is unknown...

..CONCLUSIONS: B-type natriuretic peptide levels are associated with inducible myocardial ischemia. The use of BNP levels improves the diagnostic accuracy of exercise ECG...

..To define long-term efficacy of different stent types in saphenous vein graft (SVG) interventions...

..However, a number of methodological issues have not been fully explored, including differences in HRR 1 versus 2 min after exercise termination, absolute versus relative HRR, and the impact of beta-blockers...

..INTERPRETATION: In a real-world setting, use of DES in all patients is less cost effective than in studies with selected patients. Use of these stents could be restricted to patients in high-risk groups...

..However, little is known about the impact of percutaneous coronary intervention (PCI) on left ventricular volumes and remodeling...

..Thus, the widely used strategy to increase antianginal drug therapy in elderly patients instead of evaluating them for revascularization should be reconsidered...

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..Based on the available trial evidence, an algorithm is proposed how to tailor the management strategy to each patient's individual situation...

..To assess participation rates and outcome in outpatient cardiac rehabilitation (OCR) of patients with peripheral arterial occlusive disease (PAOD)...

..Thus, CMR diagnosis of early stage ARVC is difficult and should be made with caution...

..Patients with negative STRT results after receiving therapy have a good prognosis, and their conditions may be managed conservatively...

..Diabetes mellitus (DM), particularly if insulin-dependent, is a predictor of increased perioperative risk, whereas stringent metabolic control with insulin is beneficial in the critically ill...

..Despite active research in many additional fields, the use of BNP/NT-proBNP in other settings is not yet based on solid evidence and, therefore, seems not to be useful...

..CONCLUSION: In CAD patients, the preoperative ECG contains important prognostic information and is predictive of long-term outcome independent of clinical findings and perioperative ischemia...

..CONCLUSION: The NT-proBNP level at rest as well as DeltaNT-proBNP during exercise stress testing is associated with inducible myocardial ischemia. NT-proBNP levels may have incremental value in the diagnosis of myocardial ischemia...

..These data suggest that CMR is a highly sensitive and specific method to diagnose or exclude ARVC, and thus, has an important prognostic impact on predicting arrhythmia free survival...

..Thus, coronary stent infection, although exceedingly rare, represents a life-threatening complication and should be considered in the differential diagnosis of patients presenting with fever during the first few weeks after PCI...

..A pooled analysis in cardiogenic shock due to acute coronary syndromes is desirable to assess the effect of early revascularization (ERV) across all ages and a wide spectrum of disease severity...

..In cardiogenic shock (CS), conclusive data on serial hemodynamic measurements for treatment guidance and prognosis are lacking...

..We present a case of a ruptured pulmonary artery caused by a Cournand catheter in a high-risk patient with pulmonary hypertension on oral anticoagulation with successful emergency embolization with gelatine foam...

..The aim of this study was to validate a ECG system, which allows LP analysis using X,Y, Z leads mathematically derived from the standard 12-lead ECG...

..To assess the effect of outpatient cardiac rehabilitation in important patient subgroups...

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..As patients expressed concerns regarding protection of privacy if data were accessible via internet, this would remain a strong limiting factor for online use...

..Incidence, predictors, and prognostic impact of worsening renal function (WRF) in elderly patients with chronic heart failure (HF) undergoing intensive contemporary medical therapy are unknown...

..The authors discuss the benefits and risks of interventional vs. medical management of chronic, symptomatic coronary artery disease in elderly patients in view of the TIME results and their clinical implications...

..Hypericum perforatum (St. John's wort), an increasingly used herbal antidepressant drug should be used with caution due to severe and possibly dangerous interaction with cardioactive drugs...

..Consequently, they concluded that the rate response of the CLS pacing system can be inappropriately influenced by rapid shifts of blood volume, affecting right ventricular filling...