Research Topics
Species | Luc HärterSummaryAffiliation: University Hospital Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
In vitro norepinephrine significantly activates isolated platelets from healthy volunteers and critically ill patients following severe traumatic brain injuryChristoph Tschuor
Surgical Intensive Care Medicine, University Hospital Zuerich, Raemistrasse 100, CH 8091 Zuerich, Switzerland
Crit Care 12:R80. 2008..This, in turn, could promote microthrombosis formation and induce additional brain damage...
Increased expression of toll-like receptor-2 and -4 on leukocytes from patients with sepsisLuc Härter
Division of Trauma Surgery, University Hospital Zurich, Zurich, Switzerland
Shock 22:403-9. 2004..Therefore, the endotoxin tolerance seen in patients with sepsis does not depend solely on TLR-2 or TLR-4 expression, and other mechanisms must be involved...
Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humansJohannes Wacker
Institute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Anesth Analg 106:1749-58. 2008..Sevoflurane can be used as sedative-analgesic drug with endothelial protective properties. We tested whether low-dose sevoflurane inhalation provides sustained inhibition of detrimental granulocyte-platelet aggregation in humans...
Molecular evidence of late preconditioning after sevoflurane inhalation in healthy volunteersEliana Lucchinetti
Institute of Anesthesiology, University Hospital Zurich, Switzerland
Anesth Analg 105:629-40. 2007..We hypothesized that sevoflurane inhalation would modify the transcriptome in human blood and modulate the expression of adhesion molecules in white blood cells consistent with the occurrence of a late preconditioning phase...
Vacuum-assisted closure therapy increases local interleukin-8 and vascular endothelial growth factor levels in traumatic woundsLudwig Labler
Division of Trauma Surgery, Department of Surgery, University Hospital Zurich, Zurich, Switzerland
J Trauma 66:749-57. 2009..Aim of this study was to determine the impact of VAC therapy versus alternative Epigard application on local inflammation and neovascularization in traumatic soft tissue wounds...
Pancreatic stone protein is highly increased during posttraumatic sepsis and activates neutrophil granulocytesMarius Keel
Departments of Trauma Surgery, University Hospital Zurich, Zurich, Switzerland
Crit Care Med 37:1642-8. 2009..However, after stress (e.g., anesthesia), PSP/reg levels are increased transiently in animals without pancreatic injury. Therefore, we aimed to determine whether PSP/reg is an acute-phase protein after nonpancreatic trauma...
Thiopental-induced apoptosis in lymphocytes is independent of CD95 activationMarius Keel
Department of Trauma Surgery, Division of Trauma Surgery, University Hospital Zurich, Switzerland
Anesthesiology 103:576-84. 2005..However, barbiturate-mediated neuroprotection correlates with lymphopenia, which increases the risk of infection. The mechanisms by which barbiturates lead to lymphopenia remain to be determined...
Endotoxin reduces CD95-induced neutrophil apoptosis by cIAP-2-mediated caspase-3 degradationLadislav Mica
Division of Trauma Surgery, University Hospital Zurich, Zurich, Switzerland
J Am Coll Surg 199:595-602. 2004..7 +/- 2.6%) apoptosis and degradation of caspase-3. CONCLUSIONS: Induction of cIAP-2 by endotoxins and accelerated degradation of activated caspase-3 by the proteasome might be responsible for reduced apoptosis in PMN during sepsis...
Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humansEliana Lucchinetti
Institute of Anesthesiology, University Hospital Zurich, Switzerland
Anesthesiology 106:262-8. 2007..The authors tested whether inhalation of sevoflurane at subanesthetic concentrations provides protection against postocclusive endothelial dysfunction induced by ischemia-reperfusion injury of the forearm in humans...
