A E Handschin

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Cbfa-1 (Runx-2) and osteocalcin expression by human osteoblasts in heparin osteoporosis in vitro
    Alexander E Handschin
    Department of Surgery, Research Division, University Hospital of Zurich, Switzerland
    Clin Appl Thromb Hemost 12:465-72. 2006
  2. ncbi Heparin effect on osteoblast-like cells in vitro
    A E Handschin
    University Hospital of Zurich, Zurich 8091, Switzerland
    J Cell Biochem 93:1. 2004
  3. ncbi Low molecular weight heparin-induced skin necrosis-a systematic review
    A E Handschin
    Division of Trauma Surgery, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
    Langenbecks Arch Surg 390:249-54. 2005
  4. ncbi Functional results of angular-stable plate fixation in displaced proximal humeral fractures
    Alexander E Handschin
    Division of Trauma Surgery, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
    Injury 39:306-13. 2008
  5. ncbi A comparative analysis of phenotype expression in human osteoblasts from heterotopic ossification and normal bone
    Alexander E Handschin
    Department of Surgery, Research Division, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
    Langenbecks Arch Surg 391:376-82. 2006
  6. ncbi [Surgical treatment of high-voltage electrical injuries]
    A E Handschin
    Abteilung für Plastische, Hand und Rekonstruktive Chirurgie, Universitatsspital Zurich, Switzerland
    Handchir Mikrochir Plast Chir 39:345-9. 2007
  7. ncbi Leptin increases extracellular matrix mineralization of human osteoblasts from heterotopic ossification and normal bone
    Alexander E Handschin
    Division of Plastic, Hand and Reconstructive Surgery, University Hospital of Zurich, Zurich, Switzerland
    Ann Plast Surg 59:329-33. 2007
  8. ncbi Factor V Leiden mutation and thrombotic occlusion of microsurgical anastomosis after free TRAM flap
    A E Handschin
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University Hospital of Zurich, Ramistrasse 100, Zurich, Switzerland
    Clin Appl Thromb Hemost 16:199-203. 2010
  9. ncbi Erythropoietin requires endothelial nitric oxide synthase to counteract TNF-[alpha]-induced microcirculatory dysfunction in murine striated muscle
    Claudio Contaldo
    Division of Plastic and Reconstructive Surgery, Department of Pathology, University Hospital Zurich, Zurich, Switzerland
    Shock 35:315-21. 2011
  10. ncbi Influence of brain injury on early posttraumatic bone metabolism
    Omana A Trentz
    Research Division, Institute for Clinical Chemistry, University of Zurich, Zurich, Switzerland
    Crit Care Med 33:399-406. 2005

Detail Information

Publications12

  1. ncbi Cbfa-1 (Runx-2) and osteocalcin expression by human osteoblasts in heparin osteoporosis in vitro
    Alexander E Handschin
    Department of Surgery, Research Division, University Hospital of Zurich, Switzerland
    Clin Appl Thromb Hemost 12:465-72. 2006
    ..At high doses, dalteparin caused a significant inhibition of both osteocalcin and Cbfa-1 expression in vitro. Our data support the hypothesis of a direct inhibition of osteoblast function underlying heparin osteoporosis...
  2. ncbi Heparin effect on osteoblast-like cells in vitro
    A E Handschin
    University Hospital of Zurich, Zurich 8091, Switzerland
    J Cell Biochem 93:1. 2004
  3. ncbi Low molecular weight heparin-induced skin necrosis-a systematic review
    A E Handschin
    Division of Trauma Surgery, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
    Langenbecks Arch Surg 390:249-54. 2005
    ..The aim of our systematic review is to analyse the present literature for cases of LMWH-induced skin necrosis, emphasising the pathogenesis, clinical pattern, and management of this rare side effect...
  4. ncbi Functional results of angular-stable plate fixation in displaced proximal humeral fractures
    Alexander E Handschin
    Division of Trauma Surgery, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
    Injury 39:306-13. 2008
    ..The availability of angular-stable plate/screw systems led to a euphoric use of these implants for the treatment of displaced proximal humerus fractures. The high implant costs seem to be justified by a potentially improved outcome...
  5. ncbi A comparative analysis of phenotype expression in human osteoblasts from heterotopic ossification and normal bone
    Alexander E Handschin
    Department of Surgery, Research Division, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
    Langenbecks Arch Surg 391:376-82. 2006
    ..The aims of the study were to further characterize the expression of osteoblast phenotypemarkers and to provide a comparison with other study results...
  6. ncbi [Surgical treatment of high-voltage electrical injuries]
    A E Handschin
    Abteilung für Plastische, Hand und Rekonstruktive Chirurgie, Universitatsspital Zurich, Switzerland
    Handchir Mikrochir Plast Chir 39:345-9. 2007
    ..A total of 61 patients (57 men, 4 females, mean age: 34 +/- 13 years) with high-voltage burns was included for analysis...
  7. ncbi Leptin increases extracellular matrix mineralization of human osteoblasts from heterotopic ossification and normal bone
    Alexander E Handschin
    Division of Plastic, Hand and Reconstructive Surgery, University Hospital of Zurich, Zurich, Switzerland
    Ann Plast Surg 59:329-33. 2007
    ..This mechanism may be involved in the pathogenesis of ectopic bone formation in vivo...
  8. ncbi Factor V Leiden mutation and thrombotic occlusion of microsurgical anastomosis after free TRAM flap
    A E Handschin
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University Hospital of Zurich, Ramistrasse 100, Zurich, Switzerland
    Clin Appl Thromb Hemost 16:199-203. 2010
    ..Immediate thrombectomy and repeated arteriography allowed for partial flap salvage. More data are needed to analyze the impact of hereditary thrombophilia on microvascular anastomosis failure...
  9. ncbi Erythropoietin requires endothelial nitric oxide synthase to counteract TNF-[alpha]-induced microcirculatory dysfunction in murine striated muscle
    Claudio Contaldo
    Division of Plastic and Reconstructive Surgery, Department of Pathology, University Hospital Zurich, Zurich, Switzerland
    Shock 35:315-21. 2011
    ..We conclude that EPO treatment elicits protection against TNF-[alpha]-induced microcirculatory dysfunction, depending on NO derived from endothelial cells, but not on the inducible isoform...
  10. ncbi Influence of brain injury on early posttraumatic bone metabolism
    Omana A Trentz
    Research Division, Institute for Clinical Chemistry, University of Zurich, Zurich, Switzerland
    Crit Care Med 33:399-406. 2005
    ..The lower levels of osteocalcin detected in this study may play an important role in patients with brain injury and the later development of posttraumatic heterotopic ossification...
  11. ncbi Abdominal compartment syndrome after liver transplantation
    Alexander E Handschin
    Department of Visceral and Transplant Surgery, University Hospital Zurich, Ramistr. 100, 8091 Zurich, Switzerland
    Liver Transpl 11:98-100. 2005
    ..It remains, however, a rarely described complication after liver transplantation, despite the presence of significant factors that contribute to elevated intraabdominal pressure...
  12. ncbi Atypical abdominal pain in a liver transplant recipient
    Alexander E Handschin
    Department of Visceral and Transplant Surgery, University Hospital of Zurich, Switzerland
    Liver Transpl 9:444-5. 2003