Research Topics
| F FroehlichSummaryAffiliation: University Hospital Country: Switzerland Publications
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Publications
Is age a good discriminator when deciding whether to perform gastroscopy?F Froehlich
Division of Gastroenterology PMU/CHUV, University of Lausanne, , 1005 Lausanne, Switzerland
Endoscopy 35:76-8. 2003
Obstructive fibrostenotic Crohn's diseaseFlorian Froehlich
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:29-30. 2005..Mechanical treatment methods consist of endoscopic balloon dilation, stricturoplasty or surgical resection. Fibrostenotic Crohn's disease does not respond to medical therapy and requires endoscopic or surgical treatment...
Fibrostenotic Crohn's diseaseFlorian Froehlich
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:113-5. 2007..Mechanical treatment methods consist of endoscopic balloon dilation, stricturoplasty or surgical resection. Fibrostenotic Crohn's disease does not respond to medical therapy and requires endoscopic or surgical treatment...
[Appropriateness in gastroenterology: too many endoscopies or not enough?]F Froehlich
, , Lausanne
Praxis (Bern 1994) 93:1645-7. 2004
Maintenance of surgically induced remission of Crohn's diseaseFlorian Froehlich
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:130-5. 2007..Conventional corticosteroids, budesonide or probiotics have no proven role in postoperative prophylaxis. Infliximab has not as yet been studied for use in the prevention of relapse after surgery...
Treatment of postoperative Crohn's diseaseFlorian Froehlich
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:49-53. 2005..Conventional corticosteroids, budesonide or probiotics have no proven role in postoperative prophylaxis. Infliximab has not as yet been studied for use in the prevention of relapse after surgery...
Current sedation and monitoring practice for colonoscopy: an International Observational Study (EPAGE)F Froehlich
Division of Gastroenterology, Medical Outpatient Department, PMU CHUV, University of Lausanne, Lausanne, Switzerland
Endoscopy 38:461-9. 2006..Knowledge of current practice is needed to ensure quality of care and help focus future research. The objective of this study was to examine sedation and monitoring practice in endoscopy centers internationally...
Appropriateness of gastrointestinal endoscopy: risk of complicationsF Froehlich
Policlinique Medicale Universitaire, Lausanne, Switzerland
Endoscopy 31:684-6. 1999..No formal reporting requirements exist, and most of the published studies on complications come from centres with highly-skilled endoscopists...
[Dyspepsia in 2002: which investigations, what treatment?]Florian Froehlich
, , , 1005 Lausanne
Rev Med Suisse Romande 122:429-31. 2002
Appropriateness of colonoscopy in Europe (EPAGE II). Presentation of methodology, general results, and analysis of complicationsP Juillerat
Department of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Endoscopy 41:240-6. 2009..This introductory paper therefore deals with methodology, general appropriateness, and a review of colonoscopy complications...
Appropriateness of colonoscopy in Europe (EPAGE II). Chronic diarrhea and known inflammatory bowel diseaseS Schusselé Filliettaz
Healthcare Evaluation Unit, Institute of Social and Preventive Medicine, University of Lausanne and Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Endoscopy 41:218-26. 2009....
The appropriateness of colonoscopy: a multi-center, international, observational studyJ K Harris
Institute of Social and Preventive Medicine, University of Lausanne, Lausanne, Switzerland
Int J Qual Health Care 19:150-7. 2007..To examine the appropriateness and necessity of colonoscopy across Europe...
Appropriateness of upper gastrointestinal endoscopy: comparison of American and Swiss criteriaJ P Vader
Institute of Social and Preventive Medicine, University of Lausanne, Switzerland
Int J Qual Health Care 9:87-92. 1997..Examine the reproducibility of the RAND method for developing criteria for the appropriateness of medical procedures...
Appropriate treatment for Crohn's disease: methodology and summary results of a multidisciplinary international expert panel approach--EPACTJ P Vader
Institute of Social and Preventive Medicine, University of Lausanne, 17 rue du Bugnon, CH 1005 Lausanne, Switzerland
Digestion 73:237-48. 2006..For many therapeutic decisions in Crohn's disease (CD), high-grade evidence is lacking. To assist clinical decision-making, explicit panel-based appropriateness criteria were developed by an international, multidisciplinary expert panel...
Factors associated with the technical performance of colonoscopy: An EPAGE StudyJ K Harris
Institute of Social and Preventive Medicine, University of Lausanne, Rue du Bugnon 17, CH 1005 Lausanne, Switzerland
Dig Liver Dis 39:678-89. 2007..Variations in colonoscopy practice exist, which may be related to healthcare quality...
Appropriateness of colonoscopy in Europe (EPAGE II). Functional bowel disorders: pain, constipation and bloatingS Schusselé Filliettaz
Healthcare Evaluation Unit, Institute of Social and Preventive Medicine IUMSP, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Endoscopy 41:234-9. 2009....
Appropriateness of colonoscopy in Europe (EPAGE II). Iron-deficiency anemia and hematocheziaI Peytremann-Bridevaux
Healthcare Evaluation Unit, Institute of Social and Preventive Medicine IUMSP, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Endoscopy 41:227-33. 2009....
Appropriateness of colonoscopy in Europe (EPAGE II). Surveillance after polypectomy and after resection of colorectal cancerC Arditi
Healthcare Evaluation Unit, Institute of Social and Preventive Medicine IUMSP, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Endoscopy 41:209-17. 2009....
Appropriateness of therapy for fistulizing Crohn's disease: findings from a national inflammatory bowel disease cohortV Pittet
Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland
Aliment Pharmacol Ther 32:1007-16. 2010..About 30-50% of patients with Crohn's disease (CD) develop fistulae, implying significant disease burden and complicated clinical management...
Is the diagnostic yield of upper GI endoscopy improved by the use of explicit panel-based appropriateness criteria?F Froehlich
Department of Gastroenterology, Medical Outpatient Department PMU CHUV, University of Lausanne, Switzerland
Gastrointest Endosc 52:333-41. 2000..This study explored whether detailed explicit appropriateness criteria significantly improve the diagnostic yield of upper GI endoscopy...
Appropriateness of colonoscopy in Europe (EPAGE II). Screening for colorectal cancerC Arditi
Healthcare Evaluation Unit, Institute of Social and Preventive Medicine IUMSP, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Endoscopy 41:200-8. 2009....
Do explicit appropriateness criteria enhance the diagnostic yield of colonoscopy?V de Bosset
Division of Gastroenterology, Medical Outpatient Department PMU/CHU, University of Lausanne, Switzerland
Endoscopy 34:360-8. 2002..The use of such criteria could therefore improve patient selection for colonoscopy and thus contribute to efforts aimed at enhancing the quality and efficiency of care...
Fistulizing Crohn's diseaseChristian Felley
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:109-12. 2007..Infliximab should be reserved for refractory patients. Surgery is often necessary for internal fistulas...
Fistulizing Crohn's diseaseChristian Felley
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:26-8. 2005..Infliximab should be reserved for refractory patients. Surgery is often necessary for internal fistulas...
Drug safety in Crohn's disease therapyPascal Juillerat
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:161-8. 2007....
Maintenance of medically induced remission of Crohn's diseaseJean Jacques Gonvers
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:116-29. 2007..In patients refractory to other therapies, infliximab may be effective in maintaining remission...
Maintenance of remission in Crohn's diseaseJean Jacques Gonvers
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:41-8. 2005..Patients who responded clinically to infliximab have maintained their clinical response when receiving repeat infusions at 8-week intervals. In patients refractory to other therapies, infliximab may be effective in maintaining remission...
Drug safety in the treatment of Crohn's diseasePascal Juillerat
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:8-12. 2005..The safety, dose, duration for optimal efficacy and the most frequent adverse events will be described in this article...
Treatment of gastroduodenal Crohn's diseaseChristian Mottet
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:37-40. 2005..Presence of symptoms of obstruction needs aggressive therapy. If medical therapy with steroids and immunomodulatory drugs does not alleviate the symptoms, balloon dilation and surgery are the options to consider...
Pregnancy and Crohn's diseaseChristian Mottet
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:54-61. 2005..Most drugs, including sulfasalazine, mesalazine, corticosteroids, and immunosuppressors such as azathioprine and 6-mercaptopurine, are safe, whereas methotrexate is contraindicated...
Pregnancy and breastfeeding in patients with Crohn's diseaseChristian Mottet
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:149-60. 2007..During breastfeeding, mesalazine and prednisone are considered safe, azathioprine/6-mercaptopurine, budesonide and infliximab probably safe and methotrexate is contraindicated...
Mild-to-moderate active luminal Crohn's diseasePierre Michetti
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:92-8. 2007..The role of biological therapies has not been thoroughly evaluated in patients with mild disease...
Upper gastrointestinal Crohn's diseaseChristian Mottet
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:136-40. 2007..The presence of symptoms of obstruction needs aggressive therapy. If medical therapy with steroids and immunomodulatory drugs does not alleviate the symptoms, balloon dilation and surgery are the options to consider...
EPACT II: project and methodsPascal Juillerat
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:84-91. 2007..This chapter describes in detail the process of updating the literature review and the systematic approach of the RAND Appropriateness Method used during the expert panel meeting...
Therapy of mild to moderate luminal Crohn's diseasePierre Michetti
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:13-8. 2005..The role of biological therapies in mild to moderate disease has not been thoroughly evaluated and will not be discussed here...
Extraintestinal manifestations of Crohn's diseasePascal Juillerat
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:141-8. 2007....
Severe and steroid-resistant Crohn's diseasePierre Michetti
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Digestion 76:99-108. 2007..Other fast-acting immunosuppressors showed little benefit. Surgery may be indicated in this setting. Natalizumab may prove useful in patients refractory to infliximab and other anti-TNF agents...
Extraintestinal manifestations of Crohn's diseasePascal Juillerat
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:31-6. 2005....
Evaluating appropriateness of treatment for Crohn's disease: feasibility of an explicit approachIdris Guessous
Institute of Social and Preventive Medicine, University of Lausanne, Lausanne, Switzerland
Digestion 75:46-52. 2007..The feasibility of actually documenting these situations using an explicit approach has not been examined...
Severe and steroid-resistant Crohn's diseasePierre Michetti
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland
Digestion 71:19-25. 2005..Other fast-acting immunosuppressors showed little benefit. Surgery may be indicated in this setting. Nataluzimab may prove useful in patients refractory to infliximab...
Propofol sedation during endoscopic procedures in private practice: the case for capnography to make 1-nurse endoscopy acceptableFlorian Froehlich
Gastrointest Endosc 67:1008. 2008
Endoscope once for any symptom at any age?Florian Froehlich
Gastrointest Endosc 65:358-9; author reply 359. 2007
[Quality aspects of digestive system endoscopy]Jean-Jacques Gonvers
Rev Med Suisse Romande 122:471-3. 2002
Variations in colonoscopy practice in Europe: a multicentre descriptive study (EPAGE)Jennifer K Harris
Institute for Social and Preventive Medicine, University of Lausanne, Lausanne, Switzerland
Scand J Gastroenterol 42:126-34. 2007..Examination of current practice is important for bench-marking quality. The objective of this study was to examine variations in colonoscopy practice in endoscopy centres internationally...
[Pelvic and abdominal actinomycosis. Case report and review of the literature]Laura Cirafici
, 2900 Porrentruy
Rev Med Suisse Romande 122:535-7. 2002..Treatment of this condition consists of a combination of antibiotics and surgery to achieve complete recovery...
Development of appropriateness criteria for colonoscopy: comparison between a standardized expert panel and an evidence-based medicine approachAnne Nicollier-Fahrni
Institute of Social and Preventive Medicine, University of Lausanne, Lausanne, Switzerland
Int J Qual Health Care 15:15-22. 2003..New approaches should be sought in order to systematically integrate complementary evidence obtained from clinical trials and expert panels into practice guidelines...
Rectal air suctioning to reduce patient discomfort after colonoscopy?Florian Froehlich
Gastrointest Endosc 58:166. 2003
Appropriateness of colorectal cancer screening: appraisal of evidence by expertsIsabelle Peytremann Bridevaux
Gastroenterology Department, University of Basle, Switzerland
Int J Qual Health Care 18:177-82. 2006....
Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter studyFlorian Froehlich
Department of Gastroenterology PMU/CHUV, Institute of Social and Preventive Medicine, University of Lausanne, Rue du Bugnon 44, CH-1011 Lausanne, Switzerland
Gastrointest Endosc 61:378-84. 2005..The proportion of patients who undergo polypectomy increases with higher cleansing quality, whereas colon cancer detection does not seem to critically depend on the quality of bowel preparation...
A European view of diagnostic yield and appropriateness of colonoscopyJean Jacques Gonvers
Division of Gastroenterology and Hepatology, Policlinique Medicale Universitaire, Lausanne, Switerland
Hepatogastroenterology 54:729-35. 2007..This study's purpose was to examine the relationship between appropriateness criteria and diagnostic yield of colonoscopy...
Use, appropriateness, and diagnostic yield of screening colonoscopy: an international observational study (EPAGE)Bernard Burnand
, Rue du Bugnon 17, CH-1005 Lausanne, Switzerland
Gastrointest Endosc 63:1018-26. 2006..A higher diagnostic yield in uncertain/appropriate indications suggests that the use of appropriateness criteria may enhance the efficient use of colonoscopy for screening...
The EPAGE internet guideline as a decision support tool for determining the appropriateness of colonoscopyOlivier Terraz
Institute for Social and Preventive Medicine, Lausanne, Switzerland
Digestion 71:72-7. 2005..However, its actual use will depend on the removal of certain organizational and cultural obstacles...
Patient use of the Internet for health care information in SwitzerlandJean Gabriel Jeannot
Institute of Social and Preventive Medicine, Lausanne, Switzerland
Swiss Med Wkly 134:307-12. 2004..The aim of this study was to examine for the first time the frequency of Internet use for medical purposes by patients in Switzerland...
