Stephen J Ferguson

Summary

Affiliation: University of Bern
Country: Switzerland

Publications

  1. ncbi The long-term mechanical integrity of non-reinforced PEEK-OPTIMA polymer for demanding spinal applications: experimental and finite-element analysis
    Stephen J Ferguson
    Institute for Surgical Technology and Biomechanics, MEM Research Center, University of Berne, Stauffacherstrasse 78, 3014 Bern, Switzerland
    Eur Spine J 15:149-56. 2006
  2. ncbi Enhancing the mechanical integrity of the implant-bone interface with BoneWelding technology: determination of quasi-static interfacial strength and fatigue resistance
    Stephen J Ferguson
    MEM Research Center, Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    J Biomed Mater Res B Appl Biomater 77:13-20. 2006
  3. ncbi Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface
    S J Ferguson
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Berne, Berne, Switzerland
    J Biomed Mater Res A 78:291-7. 2006
  4. ncbi Fluid flow and convective transport of solutes within the intervertebral disc
    Stephen J Ferguson
    ME Müller Institute for Surgical Technology and Biomechanics, University of Bern, Murtenstrasse 35, PO Box 8354, CH 3001 Bern, Switzerland
    J Biomech 37:213-21. 2004
  5. ncbi Biomechanics of the aging spine
    Stephen J Ferguson
    M E Müller Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Berne, Murtenstrasse 35, Postbox 8354, 3001, Berne, Switzerland
    Eur Spine J 12:S97-S103. 2003
  6. ncbi Comparative biomechanical investigation of a modular dynamic lumbar stabilization system and the Dynesys system
    Philippe Gedet
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland
    Eur Spine J 18:1504-11. 2009
  7. ncbi Biomechanical comparison of different surface modifications for dental implants
    Stephen J Ferguson
    Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland
    Int J Oral Maxillofac Implants 23:1037-46. 2008
  8. ncbi Factors influencing stresses in the lumbar spine after the insertion of intervertebral cages: finite element analysis
    Anne Polikeit
    M E Müller Institute for Biomechanics, University of Bern, Murtenstrasse 35, PO Box 30, 3010 Bern, Switzerland
    Eur Spine J 12:413-20. 2003
  9. ncbi Influence of bone marrow fat embolism on coagulation activation in an ovine model of vertebroplasty
    Jörg Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Stauffacherstrasse 78, 3014 Bern, Switzerland
    J Bone Joint Surg Am 90:349-56. 2008
  10. ncbi Vertebral endplate trauma induces disc cell apoptosis and promotes organ degeneration in vitro
    Daniel Haschtmann
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland
    Eur Spine J 17:289-99. 2008

Detail Information

Publications51

  1. ncbi The long-term mechanical integrity of non-reinforced PEEK-OPTIMA polymer for demanding spinal applications: experimental and finite-element analysis
    Stephen J Ferguson
    Institute for Surgical Technology and Biomechanics, MEM Research Center, University of Berne, Stauffacherstrasse 78, 3014 Bern, Switzerland
    Eur Spine J 15:149-56. 2006
    ..Finite element analysis supported the use of PEEK-OPTIMA for load-bearing intervertebral implants...
  2. ncbi Enhancing the mechanical integrity of the implant-bone interface with BoneWelding technology: determination of quasi-static interfacial strength and fatigue resistance
    Stephen J Ferguson
    MEM Research Center, Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    J Biomed Mater Res B Appl Biomater 77:13-20. 2006
    ..With further refinement, the BoneWelding technology may offer a quicker, simpler, and more effective method for achieving strong fixation and primary stability for fracture fixation or other orthopaedic and dental implant applications...
  3. ncbi Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface
    S J Ferguson
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Berne, Berne, Switzerland
    J Biomed Mater Res A 78:291-7. 2006
    ....
  4. ncbi Fluid flow and convective transport of solutes within the intervertebral disc
    Stephen J Ferguson
    ME Müller Institute for Surgical Technology and Biomechanics, University of Bern, Murtenstrasse 35, PO Box 8354, CH 3001 Bern, Switzerland
    J Biomech 37:213-21. 2004
    ..Further study is required to determine the significance of large solutes and the timing of their delivery for disc physiology...
  5. ncbi Biomechanics of the aging spine
    Stephen J Ferguson
    M E Müller Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Berne, Murtenstrasse 35, Postbox 8354, 3001, Berne, Switzerland
    Eur Spine J 12:S97-S103. 2003
    ..Furthermore, advancing age is not the sole factor in the degeneration of the spine. Further study is crucial for understanding the unique biomechanical function of the aging spine...
  6. ncbi Comparative biomechanical investigation of a modular dynamic lumbar stabilization system and the Dynesys system
    Philippe Gedet
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland
    Eur Spine J 18:1504-11. 2009
    ....
  7. ncbi Biomechanical comparison of different surface modifications for dental implants
    Stephen J Ferguson
    Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland
    Int J Oral Maxillofac Implants 23:1037-46. 2008
    ....
  8. ncbi Factors influencing stresses in the lumbar spine after the insertion of intervertebral cages: finite element analysis
    Anne Polikeit
    M E Müller Institute for Biomechanics, University of Bern, Murtenstrasse 35, PO Box 30, 3010 Bern, Switzerland
    Eur Spine J 12:413-20. 2003
    ..Inserting an intervertebral cage markedly changed the load transfer. The altered stress distribution may trigger bone remodelling and explain damage of the underlying vertebrae...
  9. ncbi Influence of bone marrow fat embolism on coagulation activation in an ovine model of vertebroplasty
    Jörg Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Stauffacherstrasse 78, 3014 Bern, Switzerland
    J Bone Joint Surg Am 90:349-56. 2008
    ..Thus, the effects of bone marrow fat embolism on coagulation activation during vertebroplasty were investigated with use of an animal model...
  10. ncbi Vertebral endplate trauma induces disc cell apoptosis and promotes organ degeneration in vitro
    Daniel Haschtmann
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland
    Eur Spine J 17:289-99. 2008
    ..Taken together, the short term biological response of the disc following endplate fracture exhibits characteristics, which may initiate the degeneration of the organ...
  11. ncbi Establishment of a novel intervertebral disc/endplate culture model: analysis of an ex vivo in vitro whole-organ rabbit culture system
    Daniel Haschtmann
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH 3014 Bern, Switzerland
    Spine (Phila Pa 1976) 31:2918-25. 2006
    ..Ex vivo in vitro study evaluating a novel intervertebral disc/endplate culture system...
  12. ncbi A mixed boundary representation to simulate the displacement of a biofluid by a biomaterial in porous media
    René P Widmer
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014 Bern, Switzerland
    J Biomech Eng 133:051007. 2011
    ..9895 for a one-dimensional bone core infiltration test and a 10.94-16.92% relative error for a three-dimensional spreading pattern study, respectively) between computational and experimental results...
  13. ncbi The importance of the endplate for interbody cages in the lumbar spine
    Anne Polikeit
    ME Müller Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    Eur Spine J 12:556-61. 2003
    ....
  14. ncbi Mechanical insertion properties of calcium-phosphate implant coatings
    Tobias T Hägi
    Center of Regenerative Medicine for Skeletal Tissues, Department of Clinical Research, University of Bern, Bern, Switzerland
    Clin Oral Implants Res 21:1214-22. 2010
    ..To investigate the influence of protein incorporation on the resistance of biomimetic calcium-phosphate coatings to the shear forces that are generated during implant insertion...
  15. ncbi Sildenafil prevents cardiovascular changes after bone marrow fat embolization in sheep
    Jörg Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Bern, Switzerland
    Anesthesiology 107:75-81. 2007
    ..The effect of sildenafil (phosphodiesterase inhibitor) on cardiovascular deterioration after bone marrow fat embolization was therefore investigated...
  16. ncbi Apoptosis and gene expression of collagenases but not gelatinases in rabbit disc fragment cultures
    Daniel Haschtmann
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland
    J Neurosurg Spine 8:552-60. 2008
    ....
  17. ncbi Vertebroplasty: experimental characterization of polymethylmethacrylate bone cement spreading as a function of viscosity, bone porosity, and flow rate
    Mario Loeffel
    MEM Research Center, University of Bern, Switzerland
    Spine (Phila Pa 1976) 33:1352-9. 2008
    ..This is an experimental study on an artificial vertebra model and human cadaveric spine...
  18. ncbi Simulated influence of osteoporosis and disc degeneration on the load transfer in a lumbar functional spinal unit
    Anne Polikeit
    M E Müller Research Center for Orthopaedic Surgery, M E Müller Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    J Biomech 37:1061-9. 2004
    ..If several parameters in a model are changed to simulate degeneration, it should be pointed out how each individual definition influences the overall result...
  19. ncbi Biomechanical analysis of torsion and shear forces in lumbar and lumbosacral spine segments of nonchondrodystrophic dogs
    Katharina U Hediger
    Small Animal Clinic, Department of Surgery and Radiology and the MEM Research Center for Orthopedic Surgery, University of Berne, Länggasstrasse 128, Berne, Switzerland
    Vet Surg 38:874-80. 2009
    ..To determine stiffness and load-displacement curves as a biomechanical response to applied torsion and shear forces in cadaveric canine lumbar and lumbosacral specimens...
  20. ncbi Biomechanical analysis of the three-dimensional motion pattern of the canine cervical spine segment C4-C5
    Martin Hofstetter
    Department Clinical Veterinary Medicine and the MEM Research Center, Institute for Surgical Technology and Biomechanics, Vetsuisse Faculty, University of Bern, Bern, Switzerland
    Vet Surg 38:49-58. 2009
    ..To study the kinematics of cervical spine segment C(4)-C(5) and its association with disc dimensions and the coupled motion (CM) in relation to primary motion (PM)...
  21. ncbi Scaled, patient-specific 3D vertebral model reconstruction based on 2D lateral fluoroscopy
    Guoyan Zheng
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, Bern, 3014, Switzerland
    Int J Comput Assist Radiol Surg 6:351-66. 2011
    ..g., CT acquisition). An alternative method using 2D lateral fluoroscopy was developed...
  22. ncbi The effect of cement augmentation on the load transfer in an osteoporotic functional spinal unit: finite-element analysis
    Anne Polikeit
    ME Müller Institute for Biomechanics, University of Bern, Bern, Switzerland
    Spine (Phila Pa 1976) 28:991-6. 2003
    ..The effect of cement augmentation on an osteoporotic lumbar functional spinal unit was investigated using finite-element analysis...
  23. ncbi Biological response of the intervertebral disc to repetitive short-term cyclic torsion
    Samantha C W Chan
    ARTORG, Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    Spine (Phila Pa 1976) 36:2021-30. 2011
    ..In vitro study of the biological response of the intervertebral disc (IVD) to cyclic torsion by using bovine caudal IVDs...
  24. ncbi Time and depth dependent Poisson's ratio of cartilage explained by an inhomogeneous orthotropic fiber embedded biphasic model
    Salman Chegini
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH 3014 Bern, Switzerland
    J Biomech 43:1660-6. 2010
    ..This material model's response may provide valuable new insight into potential initiation of cartilage fibrillation or delamination in whole-joint simulations...
  25. ncbi Automated cement segmentation in vertebroplasty
    Nina Kozic
    Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland
    Comput Aided Surg 15:49-55. 2010
    ..The method has been positively evaluated by physicians...
  26. ncbi Minimizing errors during in vitro testing of multisegmental spine specimens: considerations for component selection and kinematic measurement
    Philippe Gedet
    MEM Research Center, Institute for Surgical Technology and Biomechanics, University of Bern Stauffacherstrasse, 78 CH 3014 Bern, Switzerland
    J Biomech 40:1881-5. 2007
    ....
  27. ncbi Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies
    Paul A Hulme
    M E Müller Institute for Surgical Technology and Biomechanics, Bern, Switzerland
    Spine (Phila Pa 1976) 31:1983-2001. 2006
    ..Systematic literature review...
  28. ncbi Clinical measurements of cement injection pressure during vertebroplasty
    Jörg Krebs
    M E Müller Institute for Surgical Technology and Biomechanics, Bern, Switzerland
    Spine (Phila Pa 1976) 30:E118-22. 2005
    ..Clinical study of injection pressure during vertebroplasty...
  29. ncbi Numerical assessment on the effective mechanical stimuli for matrix-associated metabolism in chondrocyte-seeded constructs
    Arzu Tasci
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, Bern, Switzerland
    J Tissue Eng Regen Med 5:210-9. 2011
    ..They could also be helpful to increase the efficacy of loading protocols for avascular tissue engineering...
  30. ncbi Cardiovascular changes after pulmonary cement embolism: an experimental study in sheep
    J Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Switzerland
    AJNR Am J Neuroradiol 28:1046-50. 2007
    ..Thus, we investigated the cardiovascular changes after pulmonary cement embolism of PMMA with and without HA...
  31. ncbi Determination of vertebral endplate deformation under load using micro-computed tomography
    P A Hulme
    MEM Research Center, University of Bern, Stauffacherstrasse 78, CH 3014, Bern, Switzerland
    J Biomech 41:78-85. 2008
    ..Using this micro-CT based method, the effect of interbody implants, grafts, disc replacement strategies, and surgical procedures such as nucleotomy and vertebral cement augmentation on endplate mechanical behaviour can be ascertained...
  32. ncbi An in vitro investigation of the acetabular labral seal in hip joint mechanics
    S J Ferguson
    M E Müller Institute for Biomechanics, University of Bern, Murtenstrasse 35, Postbox 30, CH 3010, Bern, Switzerland
    J Biomech 36:171-8. 2003
    ..However, both sealing mechanisms are dependent on the fit of the labrum against the femoral head...
  33. ncbi Differences in endplate deformation of the adjacent and augmented vertebra following cement augmentation
    Paul A Hulme
    MEM Research Center, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland
    Eur Spine J 18:614-23. 2009
    ..This non-invasive micro-CT method may also be useful to investigate endplate failure, and parameters that predict vertebral failure...
  34. ncbi Plasma levels of endothelin-1 after a pulmonary embolism of bone marrow fat
    J Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Stauffacherstrasse 78, 3014 Bern, Switzerland
    Acta Anaesthesiol Scand 51:1107-14. 2007
    ..The role of ET-1 in the development of acute cardiovascular deterioration as a result of bone marrow fat embolization during vertebroplasty was therefore investigated...
  35. ncbi Regional variation in vertebral bone morphology and its contribution to vertebral fracture strength
    P A Hulme
    MEM Research Center, University of Bern, Stauffacherstrasse 78, CH 3014, Bern, Switzerland
    Bone 41:946-57. 2007
    ..Our results show the importance of considering regional variations in cancellous BAPs and disc health when assessing fracture risk...
  36. ncbi Fracture of the vertebral endplates, but not equienergetic impact load, promotes disc degeneration in vitro
    Stefan Dudli
    Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH 3014 Bern, Switzerland
    J Orthop Res 30:809-16. 2012
    ..Group B compared to control only showed small changes in mRNA levels. Our findings demonstrate that burst endplates, but not equienergetic loading, promotes DD...
  37. ncbi Biomechanical comparison of the sandblasted and acid-etched and the machined and acid-etched titanium surface for dental implants
    Dehua Li
    Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Berne, Freiburgstrasse 7, CH-3010 Berne, Switzerland
    J Biomed Mater Res 60:325-32. 2002
    ....
  38. ncbi 2D/3D reconstruction of a scaled lumbar vertebral model from a single fluoroscopic image
    Guoyan Zheng
    Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland
    Conf Proc IEEE Eng Med Biol Soc 2010:4395-8. 2010
    ..An average error of 1.0 mm was found when the present technique was used to reconstruct the surface models of all twelve lumbar vertebrae...
  39. ncbi Anterior fixation in the osteoporotic spine: cut-out and pullout characteristics of implants
    Stephen J Ferguson
    ME Müller Institute for Biomechanics, University of Bern, Murtenstrasse 35, Postbox 30, 3010 Bern, Switzerland
    Eur Spine J 11:527-34. 2002
    ..The SpiralBlade may be an alternative to anterior screw fixation in the osteoporotic spine, offering the same cut-out resistance with one implant rather than two screws...
  40. ncbi Cardiovascular changes after pulmonary embolism from injecting calcium phosphate cement
    Jörg Krebs
    MEM Research Center, Institute for Surgical Technology and Biomechanics, Medical Faculty, University of Bern, Switzerland
    J Biomed Mater Res B Appl Biomater 82:526-32. 2007
    ..Reliable cohesion of CaP cements in an aqueous environment is essential for clinical applications such as osteoporotic bone augmentation...
  41. ncbi Adjacent vertebral failure after vertebroplasty. A biomechanical investigation
    U Berlemann
    Department of Orthopaedic Surgery, Inselspital Bern, University of Bern, Switzerland
    J Bone Joint Surg Br 84:748-52. 2002
    ..Further investigation is required to determine an optimal protocol for augmentation...
  42. ncbi The effects of impingement and dysplasia on stress distributions in the hip joint during sitting and walking: a finite element analysis
    Salman Chegini
    MEM Research Center for Orthopaedic Surgery, University of Bern, Bern, Switzerland
    J Orthop Res 27:195-201. 2009
    ..Hip joint morphological parameters that minimized were 20 degrees <or= CE <or= 30 degrees and alpha <or= 50 degrees ...
  43. ncbi Evaluation of chemically modified SLA implants (modSLA) biofunctionalized with integrin (RGD)- and heparin (KRSR)-binding peptides
    Nina Broggini
    Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Berne, Freiburgstrasse 7, CH 3010 Berne, Switzerland
    J Biomed Mater Res A 100:703-11. 2012
    ..62%) demonstrated no significant differences among treatments. It may be concluded that biofunctionalizing modSLA surfaces with KRSR and RGD derivatives of PLL-g-PEG polymer does not increase BIC, bone fill, or interfacial shear strength...
  44. ncbi Three-dimensional motion pattern of the caudal lumbar and lumbosacral portions of the vertebral column of dogs
    Monika I Benninger
    Division of Radiology, Department of Clinical Veterinary Medicine, University of Bern, , 3001 Bern, Switzerland
    Am J Vet Res 65:544-51. 2004
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that motion in the caudal lumbar and lumbosacral portions of the vertebral column of dogs is complex and provided a basis for further studies evaluating abnormal vertebral columns...
  45. ncbi Influence of diurnal hyperosmotic loading on the metabolism and matrix gene expression of a whole-organ intervertebral disc model
    Daniel Haschtmann
    MEM Research Center for Orthopaedic Surgery, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH 3014 Bern, Switzerland
    J Orthop Res 24:1957-66. 2006
    ..In conclusion, diurnal hyper-osmotic stimulation of a whole-organ disc/endplate culture partially inhibits a matrix gene expression profile as encountered in degenerative disc disease and counteracts cellular metabolic hypo-activity...
  46. ncbi Posterior thoracic extrapedicular fixation: a biomechanical study
    Walter Morgenstern
    Department of Orthopaedic Surgery, Kantonsspital St. Gallen, Switzerland
    Spine 28:1829-35. 2003
    ..CONCLUSIONS: The extrapedicular technique provides a construct for stabilization of the thoracic spine that is as rigid as the conventional intrapedicular technique, but has the advantage of a safer surgical screw insertion...
  47. ncbi [Elbow dysplasia in the dog: finite element analysis]
    Anne Polikeit
    Zürcher Hochschule Winterthur, Departement Technik, Informatik und Naturwissenschaften, Institut für mechanische Systeme, Winterthur, Switzerland
    Biomed Tech (Berl) 52:308-14. 2007
    ..The results obtained support empirical observations made during years of experience and offer explanations for clinical findings that are not yet well understood...
  48. ncbi Primary stability of a robodoc implanted anatomical stem versus manual implantation
    Michael Nogler
    Department of Orthopaedic Surgery, University of Innsbruck, Austria, Anichstrasse 35, A 6020 Innsbruck, Austria
    Clin Biomech (Bristol, Avon) 19:123-9. 2004
    ..To assess the initial stability of anatomical stems implanted in manually broached femoral cavities compared with that assessed in cavities milled with the robodoc system...
  49. ncbi Effects of anatomic conformation on three-dimensional motion of the caudal lumbar and lumbosacral portions of the vertebral column of dogs
    Monika I Benninger
    Division of Radiology, Department of Clinical Veterinary Medicine, Vetsuisse-Faculty of Bern, , 3001 Bern, Switzerland
    Am J Vet Res 67:43-50. 2006
    ..In vivo dynamic measurements of the 3-D motion pattern of the lumbar and lumbosacral portions of the vertebral column will be necessary to further assess biomechanics that could lead to disk degeneration in dogs...