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Species | Louis Du PasquierSummaryAffiliation: University of Basel Country: Switzerland Publications
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Publications
A human TAPBP (TAPASIN)-related gene, TAPBP-RMichelle S Teng
Immunology Division, Department of Pathology, Cambridge, GB
Eur J Immunol 32:1059-68. 2002..TAPASIN-R lacks an obvious ER retention signal. The function of TAPASIN-R will be of interest in regards to the evolution of the immune system as well as antigen processing...- The Dscam homologue of the crustacean Daphnia is diversified by alternative splicing like in insectsDaniela Brites
Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, Switzerland
Mol Biol Evol 25:1429-39. 2008..The genealogy of the Dscam gene family from vertebrates and invertebrates confirmed that the highly diversified form of the gene evolved from a nondiversified form before the split of insects and crustaceans... - Fish 'n' TRIMsLouis Du Pasquier
University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgasse 1, Basel CH 4051, Switzerland
J Biol 8:50. 2009..The history of these receptors involves ancient linkage to paralogs of the major histocompatibility complex, and the family has invertebrate precursors... - Duplication and MHC linkage of the CTX family of genes in Xenopus and in mammalsL Du Pasquier
Basel Institute for Immunology, Switzerland
Eur J Immunol 29:1729-39. 1999..Some human CTX homologies are on chromosomes 11 and 21, but others are on chromosomes 1, 6 and 19, which contain MHC paralogous regions; this suggests that a very ancient linkage group has been preserved... - Immunology. Insects diversify one molecule to serve two systemsLouis Du Pasquier
Institute of Zoology and Evolutionary Biology, University of Basel, Vesalgasse 1, CH-4051 Basel, Switzerland
Science 309:1826-7. 2005 - Germline and somatic diversification of immune recognition elements in MetazoaLouis Du Pasquier
University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgassel, CH 4051 Basel, Switzerland
Immunol Lett 104:2-17. 2006..Metazoa had to adapt to the conditions generated by this diversity: the control of expression of multiple genes and the risk of autoimmunity... - Innate immunity in early chordates and the appearance of adaptive immunityLouis Du Pasquier
Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
C R Biol 327:591-601. 2004..In this way the adaptive immune system could have developed from a set of receptors involved in a primitive local innate immunity involving NF-kappaB-mediated apoptosis... - Immunoglobulin superfamily receptors in protochordates: before RAG timeLouis Du Pasquier
Institute of Zoology, University of Basel, Basel, Switzerland
Immunol Rev 198:233-48. 2004.... - Speculations on the origin of the vertebrate immune systemLouis Du Pasquier
Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
Immunol Lett 92:3-9. 2004..The role of virus receptor for many of these clustered genes products provides perhaps one way of envisaging the recruitment of this family in the adaptive immune system from an ancient form of innate antiviral immunity... - The fate of duplicated immunity genes in the dodecaploid Xenopus ruwenzoriensisLouis Du Pasquier
University of Basel, Department of Zoology and Evolutionary Biology University of Basel Vesalgasse 1 CH 4051 Basel Switzerland
Front Biosci 14:177-91. 2009..laevis versus 4 in X. ruwenzoriensis. One interpretation is that natural selection acts more on the number of genes than on the mode of inheritance (polysomic versus disomic)... - Workshop report: evolutionary immunobiology--new approaches, new paradigmsLouis Du Pasquier
Department of Zoology, University of Basel, Rheinsprung 9, CH-4051 Basel, Switzerland
Dev Comp Immunol 27:263-71. 2003 - [Metazoa immune receptors diversification during evolution]Louis Du Pasquier
Université de Bâle, Institut de Zoologie et de Biologie évolutive, Vesalgasse 1, CH 4051 Basel, Switzerland
Med Sci (Paris) 25:273-80. 2009..At all levels many convergences reveal even better than conservations the intensity of pressure exerted on the immune systems to diversify their immunoreceptors in front of the changing environment... - B-cell development in the amphibian XenopusL Du Pasquier
Basel Institute for Immunology, Switzerland
Immunol Rev 175:201-13. 2000..Switch from IgM to other isotypes is mediated by loop-excision deletion of the IgM constant region gene via switch regions which, unlike their mammalian counterpart, are A-T rich and reveal conserved microsites for the breakpoints... - Meeting the demand for innate and adaptive immunities during evolutionL Du Pasquier
University of Basel, Institute of Zoology, Basel, Switzerland
Scand J Immunol 62:39-48. 2005.... - The fate of duplicated major histocompatibility complex class Ia genes in a dodecaploid amphibian, Xenopus ruwenzoriensisBenedicte Sammut
Basel Institute for Immunology, Switzerland
Eur J Immunol 32:2698-709. 2002..This is a rare situation among vertebrates. The observed polymorphism is most likely due to the interlocus genetic exchanges related to the peculiar mode of speciation of the genus... - Population genetics of duplicated alternatively spliced exons of the Dscam gene in Daphnia and DrosophilaDaniela Brites
Zoologisches Institut, Evolutionsbiologie, University of Basel, Basel, Switzerland
PLoS ONE 6:e27947. 2011.... - Cloning of the unculturable parasite Pasteuria ramosa and its Daphnia host reveals extreme genotype-genotype interactionsPepijn Luijckx
Institut of Zoology, Evolutionsbiologie, University of Basel, Basel, Switzerland
Ecol Lett 14:125-31. 2011..We recommend caution when using P. ramosa isolates as the presence of multiple genotypes may influence the outcome and interpretation of some experiments... - The fate of duplicated major histocompatibility complex class Ia genes in a dodecaploid amphibian, Xenopus ruwenzoriensisBenedicte Sammut
Basel Institute for Immunology, Basel, Switzerland
Eur J Immunol 32:1593-604. 2002..This is a rare situation among vertebrates. The observed polymorphism is most likely due to the interlocus genetic exchanges related to the peculiar mode of speciation of the genus... - Evolution of innate and adaptive immunity: can we draw a line?Martin F Flajnik
Department of Microbiology and Immunology, University of Maryland at Baltimore School of Medicine, Baltimore, MD 21201 1559, USA
Trends Immunol 25:640-4. 2004..Although we draw no startling conclusions, we hope to encourage different thought patterns when viewing immune systems... - Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contactsFrank Wegmann
Institute of Cell Biology, ZMBE, University of Muenster, 48149 Muenster, Germany
Exp Cell Res 300:121-33. 2004..In CHO cells, recruitment of MAGI-1 to cell contacts required the presence of ESAM. Hence, ESAM may be involved in anchoring MAGI-1 at endothelial tight junctions... - A novel family of diversified immunoregulatory receptors in teleosts is homologous to both mammalian Fc receptors and molecules encoded within the leukocyte receptor complexJames L Stafford
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216-4505, USA
Immunogenetics 58:758-73. 2006.... - Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: "waiting for Godot"Kaoru Azumi
Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
Immunogenetics 55:570-81. 2003..However, there are key V regions, the essential feature of an immunoglobulin superfamily VC1-like core, and possible proto-MHC regions scattered throughout the genome waiting for Godot... - An evolutionarily conserved target motif for immunoglobulin class-switch recombinationAli A Zarrin
Howard Hughes Medical Institute, The Children's Hospital, CBR Institute for Biomedical Research, and Department of Genetics, Harvard University Medical School, Boston, Massachusetts 02115, USA
Nat Immunol 5:1275-81. 2004..We propose that AGCT is a primordial CSR motif that targets AID through a non-R-loop mechanism involving an AID-replication protein A complex... - Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and futureMarc Daëron
Institut Pasteur, Departement d Immunologie, Unité d Allergologie Moléculaire et Cellulaire, Paris, France
Immunol Rev 224:11-43. 2008.... - ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structuresIvana Zucchetti
Laboratory of Cell Biology, Stazione Zoologica Anton Dohrn Villa Comunale, 80121 Naples, Italy
Differentiation 76:267-82. 2008..These findings suggest that ciCD94-1 has different roles in immunity and in development, thus strengthening the concept of gene co-option during evolution and of an evolutionary relationship between the nervous and the immune systems... - The chicken leukocyte receptor complex encodes a primordial, activating, high-affinity IgY Fc receptorBirgit C Viertlboeck
Institute for Animal Physiology, University of Munich, 80539 Munich, Germany
Proc Natl Acad Sci U S A 104:11718-23. 2007..CHIR-AB1 thus represents a primordial Fc receptor that combines features of different mammalian counterparts... - Channel catfish leukocyte immune-type receptors contain a putative MHC class I binding siteJames L Stafford
Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216 4505, USA
Immunogenetics 59:77-91. 2007..Taken together, these results suggest that fish LITRs have an orthologous relationship to LRC-encoded receptors such as the human LILRs and could potentially function as a diverse family of MHC class I-binding receptors... - Costimulatory receptors in jawed vertebrates: conserved CD28, odd CTLA4 and multiple BTLAsDavid Bernard
Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, 78352 Jouy en Josas Cedex, France
Dev Comp Immunol 31:255-71. 2007..The genomic localization of these genes in vertebrate genomes supports the split between the BTLA and CD28 families... - The chicken leukocyte receptor complex: a highly diverse multigene family encoding at least six structurally distinct receptor typesBirgit C Viertlboeck
Institute for Animal Physiology, University of Munich, Munich, Germany
J Immunol 175:385-93. 2005..Fluorescence in situ hybridization localized the CHIR gene cluster to microchromosome 31 and identified this region as orthologous to the human leukocyte receptor complex...