Research Topics
Species | Lasse R BraathenSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005Lasse R Braathen
Dermatological University Clinic, Bern, Switzerland
J Am Acad Dermatol 56:125-43. 2007..PDT may also be a means of preventing certain nonmelanoma skin cancers in immunosuppressed patients...
Interleukin-2 primes eosinophil degranulation in hypereosinophilia and Wells' syndromeHans Uwe Simon
Department of Pharmacology, University of Bern, Bern, Switzerland
Eur J Immunol 33:834-9. 2003..These data suggest that patients with increased eosinophil surface CD25 expression are at higher risk of eosinophil degranulation and subsequent tissue damage when IL-2 is present at inflammatory sites...
Eosinophilic fasciitis (Shulman syndrome)Sandro Mosconi
Dermatological Clinic, Inselspital, University of Berne, Switzerland
Dermatology 205:204-6. 2002..Circulating antibodies against Borrelia burgdorferi were detected. The association of B. burgdorferi infection with eosinophilic fasciitis is discussed...
Detection of perforin and granzyme B mRNA expressing cells in lichen sclerosusRobert E Hunger
Department of Dermatology, University of Bern, Inselspital, 3010 Bern, Switzerland
Exp Dermatol 16:416-20. 2007..These findings provide evidence that cell-mediated cytotoxicity plays a significant role in tissue destruction in lichen sclerosus...
Benefits from the use of a pimecrolimus-based treatment in the management of atopic dermatitis in clinical practice. Analysis of a Swiss cohortDagmar Simon
Department of Dermatology, University Hospital Bern, Bern, Switzerland
Dermatology 213:313-8. 2006..Controlled studies established the efficacy and good tolerability of pimecrolimus cream 1% for the treatment of atopic dermatitis but they may not reflect real-life use...
Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesionsDagmar Simon
Department of Dermatology, University of Bern, Bern, Switzerland
Exp Dermatol 15:441-6. 2006....
Anti-interleukin-5 antibody therapy in eosinophilic diseasesDagmar Simon
Department of Dermatology, Inselspital, Bern, Switzerland
Pathobiology 72:287-92. 2005..The decrease of tissue eosinophils was, however, less dramatic. Investigating the effects of anti-IL-5 therapy will improve our understanding of the pathogenic roles of both IL-5 and eosinophils in eosinophilic inflammatory responses...
Disseminated Mycobacterium marinum infection with extensive cutaneous eruption and bacteremia in an immunocompromised patientMarkus Streit
Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland
Eur J Dermatol 16:79-83. 2006..After four months, doxycycline had to be added because of new skin lesions. This case illustrates the impact of Mycobacterium marinum infection in immunocompromised patients...
The interleukin-13 production by peripheral blood T cells from atopic dermatitis patients does not require CD2 costimulationDagmar Simon
Department of Dermatology, University of Bern, Bern, Switzerland
Int Arch Allergy Immunol 132:148-55. 2003..Although allergic mechanisms appear to be important, the pathogenesis of both extrinsic and intrinsic forms of atopic dermatitis (AD) is unknown...
Reduced dermal infiltration of cytokine-expressing inflammatory cells in atopic dermatitis after short-term topical tacrolimus treatmentDagmar Simon
Department of Dermatology, University of Bern, Switzerland
J Allergy Clin Immunol 114:887-95. 2004..In several clinical studies, topical calcineurin inhibitors have been shown to be effective in the treatment of atopic dermatitis (AD). They target signaling pathways that control gene expression, particularly the expression of cytokines...
Increased expression and a potential anti-inflammatory role of TRAIL in atopic dermatitisEkatherina Vassina
Department of Pharmacology, University of Bern, Bern, Switzerland
J Invest Dermatol 125:746-52. 2005..Moreover, increased expression of IL-1Ra was observed in keratinocytes of AD lesional skin. These data suggest that TRAIL-expressing inflammatory skin cells may contribute to the epidermal activation of the IL-1Ra gene in AD...
Alopecia areata universalis elicited during treatment with adalimumabNedzmidin Pelivani
Department of Dermatology, Inselspital, University of Bern, Bern, Switzerland
Dermatology 216:320-3. 2008..In addition, immunofluorescence staining for TNF-alpha was found in the mononuclear cell infiltrate. This case suggests a complex role of TNF-alpha in the induction of AA...
Photodynamic therapy for non-melanoma skin cancerRolf Markus Szeimies
Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg, Germany
Acta Derm Venereol 85:483-90. 2005..For actinic keratosis and basal cell carcinoma, methyl aminolevulinate-photodynamic therapy is already approved in Europe, Australia and New Zealand, and is now also approved for actinic keratosis in the US...
Rapid resolution of toxic epidermal necrolysis with anti-TNF-alpha treatmentRobert E Hunger
J Allergy Clin Immunol 116:923-4. 2005
Efalizumab-associated papular psoriasisAkmal S Hassan
Department of Dermatology, University of Bern, Inselspital, 3010 Bern, Switzerland
Arch Dermatol 143:900-6. 2007..Some of the patients develop new papular lesions during treatment, which are predominantly located in the flexural regions...
Hypersensitivity reaction against patent blue during sentinel lymph node removal in three melanoma patientsBeat Keller
Department of Dermatology, University of Bern, Inselspital, 3010 Bern, Switzerland
Am J Surg 193:122-4. 2007..Life-threatening side effects such as allergic reactions to the injected dye have been described. We report 3 cases with systemic allergic reactions...
Eosinophilic esophagitis is frequently associated with IgE-mediated allergic airway diseasesDagmar Simon
J Allergy Clin Immunol 115:1090-2. 2005
Topical application of the tumour necrosis factor-alpha antibody infliximab improves healing of chronic woundsMarkus Streit
Department of Dermatology, Kantonsspital, Aarau, Switzerland
Int Wound J 3:171-9. 2006..Randomised controlled studies should be conducted to further evaluate the effect of topical infliximab on chronic wound healing...
Imiquimod treatment of lentigo maligna: an open-label study of 34 primary lesions in 32 patientsUrs V Buettiker
Arch Dermatol 144:943-5. 2008
