Research Topics
| Claudine KraftSummaryAffiliation: Swiss Federal Institute of Technology Country: Switzerland Publications
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Detail Information
Publications
Selective types of autophagy in yeastClaudine Kraft
Institute of Biochemistry, HPM, ETH Honggerberg, 8093 Zurich, Switzerland
Biochim Biophys Acta 1793:1404-12. 2009..In addition, we will discuss some selective types of autophagy, which have so far only been described in higher eukaryotes...- Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin proteaseClaudine Kraft
Institute of Biochemistry, HPM, ETH Honggerberg, 8093 Zurich, Switzerland
Nat Cell Biol 10:602-10. 2008..Taken together, our results suggest a link between ubiquitination and the regulated degradation of mature ribosomes by autophagy... - Is the Rsp5 ubiquitin ligase involved in the regulation of ribophagy?Claudine Kraft
Institute of Biochemistry, HPM, ETH Honggerberg, Zurich, Switzerland
Autophagy 4:838-40. 2008..Here we present data on a potential role of the ubiquitin ligase Rsp5 as a positive regulator of ribophagy, and discuss the possible involvement of ubiquitin as a signaling molecule in this process... - Activation of Atg1 kinase in autophagy by regulated phosphorylationMonika Kijanska
Institute of Biochemistry, Department of Biology, ETH Züric, Zurich, Switzerland
Autophagy 6:1168-78. 2010..Taken together, our data suggest that phosphorylation of Atg1 on multiple sites provides critical mechanisms to regulate Atg1 function in autophagy and the Cvt pathway... - Selective autophagy: ubiquitin-mediated recognition and beyondClaudine Kraft
Institute of Biochemistry, ETH Zurich, Schafmattstrasse 18, CH 8093 Zurich, Switzerland
Nat Cell Biol 12:836-41. 2010..On the basis of the evolutionary history of autophagic ubiquitin receptors, we propose a common origin for metazoan ubiquitin-dependent autophagy and the cytoplasm-to-vacuole targeting pathway of yeast... - Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeastBernd Bodenmiller
Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland
Sci Signal 3:rs4. 2010..Our results serve to constrain future models of cellular signaling and reinforce the idea that simple linear representations of signaling pathways might be insufficient for drug development and for describing organismal homeostasis... - The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substratesClaudine Kraft
Research Institute of Molecular Pathology, Dr Bohr Gasse 7, A 1030 Vienna, Austria
Mol Cell 18:543-53. 2005..Our data imply that APC/C is activated by the association of Cdh1 with Cdc27, which enables APC/C to recognize the D box of substrates via Cdh1's propeller domain... - Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complexClaudine Kraft
Research Institute of Molecular Pathology (IMP, Dr. Bohr-Gasse 7, 1030 Vienna, Austria
Methods 38:39-51. 2006..We also describe procedures to analyze the ubiquitination activity associated with recombinant Apc11... - Ribophorin I associates with a subset of membrane proteins after their integration at the sec61 transloconCornelia M Wilson
Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, United Kingdom
J Biol Chem 280:4195-206. 2005..Alternatively ribophorin I may be multifunctional and facilitate additional processes, for example, ER quality control... - Mitotic regulation of the human anaphase-promoting complex by phosphorylationClaudine Kraft
Research Institute of Molecular Pathology IMP, Dr Bohr Gasse 7, 1030 Vienna, Austria
EMBO J 22:6598-609. 2003..Plk1 depletion neither prevents APC phosphorylation nor cyclin A destruction in vivo. These observations imply that APC activation is initiated by Cdk1 already in the nuclei of late prophase cells...