Research Topics
Species | Tiziana AdageSummaryAffiliation: Merck Serono Country: Switzerland Publications
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Detail Information
Publications
In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic propertiesTiziana Adage
Merck Serono Ivrea Research Center, RBM S p a, Colleretto Giacosa, Italy
Eur Neuropsychopharmacol 18:200-14. 2008..i.d.) was able to normalize PCP-induced hyperlocomotion. These results suggest that AS057278 has the potential to anti-psychotic action toward both cognitive and positive symptoms of schizophrenia...
A novel role for receptor like protein tyrosine phosphatase zeta in modulation of sensorimotor responses to noxious stimuli: evidences from knockout mice studiesDavid Lafont
Istituto di Ricerche Biomediche A Marxer, Merck Serono Ivrea Research Centre, 10010 Colleretto Giacosa TO, Italy
Behav Brain Res 201:29-40. 2009..Moreover, RPTPz -/- mice displayed reduced responses to moderate thermal and tactile stimuli, both in baseline and under inflammatory conditions. These findings assign novel functional role of RPTPz in motor coordination and nociception...
Feeding and temperature responses to intravenous leptin infusion are differential predictors of obesity in ratsMarie-Pierre Ruffin
Department of Animal Physiology, University of Groningen, P. O. Box 14, 9750 AA Haren, The Netherlands
Am J Physiol Regul Integr Comp Physiol 286:R756-63. 2004..It is concluded that leptin's reduced efficacy to suppress food intake could predict obesity on an HED. An unexpected orexigenic effect of leptin might potentially contribute to this as well...
