Research Topics
Species | Raphael RoduitSummaryAffiliation: Institut de Recherche en Ophtalmologie Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cellsRaphael Roduit
IRO, Institut de Recherche en Ophtalmologie, Gd Champsec 64, 1950, Sion, Switzerland
Apoptosis 13:343-53. 2008..The use of specific kinases inhibitors may provide excellent tools to prevent RPE apoptosis specifically in RPE diseases involving ROS and other stress-related compounds such as in AMD...
Mutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRXRaphael Roduit
IRO, Institute for Research in Ophthalmology, Sion, Switzerland
PLoS ONE 4:e7379. 2009..NR2E3 and CRX have been shown to physically interact in vitro through their respective DNA-binding domains (DBD). The DBD also contributes to homo- and heterodimerization of nuclear receptors...
Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same familyPascal Escher
Institut de Recherche en Ophtalmologie, Sion, Switzerland
Hum Mutat 30:342-51. 2009..R311Q mutation. Finally, the functional dominance of the p.R311Q variant to the p.G56R mutation is discussed...
Acute hypoglycemia induces retinal cell death in mouseMartine Emery
Institute for Research in Ophthalmology, Sion, Switzerland
PLoS ONE 6:e21586. 2011..Therefore, we decided to study the role of acute hypoglycemia in mouse retina...
