Sandra Cottet

Summary

Affiliation: Institut de Recherche en Ophtalmologie
Country: Switzerland

Publications

  1. ncbi Triggering of Bcl-2-related pathway is associated with apoptosis of photoreceptors in Rpe65-/- mouse model of Leber's congenital amaurosis
    Sandra Cottet
    Institute for Research in Ophthalmology IRO, Avenue Grand Champsec 64, 1950, Sion 4, Switzerland
    Apoptosis 13:329-42. 2008
  2. ncbi Mechanisms of apoptosis in retinitis pigmentosa
    Sandra Cottet
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Curr Mol Med 9:375-83. 2009
  3. ncbi Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice
    Pascal Escher
    Institute for Research in Ophthalmology, Sion, Switzerland
    Mol Vis 14:2126-35. 2008
  4. ncbi Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice
    Pascal Escher
    Institute for Research in Ophthalmology, Sion, Switzerland
    Invest Ophthalmol Vis Sci 52:5933-40. 2011
  5. ncbi Bax-induced apoptosis in Leber's congenital amaurosis: a dual role in rod and cone degeneration
    Séverine Hamann
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    PLoS ONE 4:e6616. 2009
  6. ncbi Altered expression of ?-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber's congenital amaurosis
    Joane Le Carré
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Mol Vis 17:1287-97. 2011
  7. ncbi Biological characterization of gene response in Rpe65-/- mouse model of Leber's congenital amaurosis during progression of the disease
    Sandra Cottet
    Institute of Research in Ophthalmology, Sion, Switzerland
    FASEB J 20:2036-49. 2006
  8. ncbi Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes
    Sylviane Métrailler
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Exp Eye Res 96:70-81. 2012
  9. ncbi cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells
    Sandra Cottet
    Institute of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland
    Diabetes 51:1805-14. 2002

Collaborators

Detail Information

Publications9

  1. ncbi Triggering of Bcl-2-related pathway is associated with apoptosis of photoreceptors in Rpe65-/- mouse model of Leber's congenital amaurosis
    Sandra Cottet
    Institute for Research in Ophthalmology IRO, Avenue Grand Champsec 64, 1950, Sion 4, Switzerland
    Apoptosis 13:329-42. 2008
    ..They further highlight a new regulatory mechanism of Bax-dependent apoptosis based on regulated expression and activation of specific isoforms of this protein...
  2. ncbi Mechanisms of apoptosis in retinitis pigmentosa
    Sandra Cottet
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Curr Mol Med 9:375-83. 2009
    ..Modulation of common apoptotic signaling pathways may be of outstanding potential to target multiple retinal dystrophies regardless of the primary genetic defect...
  3. ncbi Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice
    Pascal Escher
    Institute for Research in Ophthalmology, Sion, Switzerland
    Mol Vis 14:2126-35. 2008
    ..To validate these data, we analyzed this differential expression in more detail by characterizing retinal NGC mRNA isoform and protein expression during disease progression...
  4. ncbi Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice
    Pascal Escher
    Institute for Research in Ophthalmology, Sion, Switzerland
    Invest Ophthalmol Vis Sci 52:5933-40. 2011
    ..Mef2c-dependent expression of photoreceptor-specific genes was further addressed...
  5. ncbi Bax-induced apoptosis in Leber's congenital amaurosis: a dual role in rod and cone degeneration
    Séverine Hamann
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    PLoS ONE 4:e6616. 2009
    ..These results highlight the necessity to investigate and understand the specific death signaling pathways committed in rods and cones to develop effective therapeutic approaches to treat RP diseases...
  6. ncbi Altered expression of ?-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber's congenital amaurosis
    Joane Le Carré
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Mol Vis 17:1287-97. 2011
    ..Additionally, we assessed the expression of the other members of this protein family, including ?-galactosidase-1 (Glb1), ?-galactosidase-1-like (Glb1l), and ?-galactosidase-1-like protein 2 (Glb1l2)...
  7. ncbi Biological characterization of gene response in Rpe65-/- mouse model of Leber's congenital amaurosis during progression of the disease
    Sandra Cottet
    Institute of Research in Ophthalmology, Sion, Switzerland
    FASEB J 20:2036-49. 2006
    ....
  8. ncbi Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes
    Sylviane Métrailler
    IRO, Institute for Research in Ophthalmology, Sion, Switzerland
    Exp Eye Res 96:70-81. 2012
    ..These events may determine retinal cell fate, progression and severity of the disease...
  9. ncbi cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells
    Sandra Cottet
    Institute of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland
    Diabetes 51:1805-14. 2002
    ....