Sami Damak

Summary

Country: Switzerland

Publications

  1. ncbi Transsynaptic transport of wheat germ agglutinin expressed in a subset of type II taste cells of transgenic mice
    Sami Damak
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, New York, 10029, USA
    BMC Neurosci 9:96. 2008
  2. ncbi Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    BMC Biol 4:7. 2006
  3. ncbi Umami taste responses are mediated by alpha-transducin and alpha-gustducin
    Wei He
    Department of Physiology and Biophysics, The Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 24:7674-80. 2004
  4. ncbi Signal transduction of umami taste: insights from knockout mice
    Minqing Rong
    Department of Physiology and Biophysics, Howard Hughes Medical Institute, The Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA
    Chem Senses 30:i33-4. 2005
  5. ncbi Trpm5 null mice respond to bitter, sweet, and umami compounds
    Sami Damak
    Department of Neuroscience, The Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029, USA
    Chem Senses 31:253-64. 2006
  6. ncbi Detection of sweet and umami taste in the absence of taste receptor T1r3
    Sami Damak
    Department of Biophysics and Physiology, Mount Sinai School of Medicine, Box 1677, 1425 Madison Avenue, New York, NY 10029, USA
    Science 301:850-3. 2003
  7. ncbi Contribution of alpha-gustducin to taste-guided licking responses of mice
    John I Glendinning
    Department of Biological Science, Barnard College, Columbia University, 3009 Broadway, New York, NY 10027, USA
    Chem Senses 30:299-316. 2005
  8. ncbi Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin
    Wei He
    Department of Physiology and Biophysics, Howard Hughes Medical Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, NY 10029, USA
    Chem Senses 27:719-27. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Transsynaptic transport of wheat germ agglutinin expressed in a subset of type II taste cells of transgenic mice
    Sami Damak
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, New York, 10029, USA
    BMC Neurosci 9:96. 2008
    ..To determine how WGA produced in T1r3-expressing taste cells is transported into gustatory neurons, transgenic mice expressing WGA-IRES-GFP driven by the T1r3 promoter were generated...
  2. ncbi Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    BMC Biol 4:7. 2006
    ....
  3. ncbi Umami taste responses are mediated by alpha-transducin and alpha-gustducin
    Wei He
    Department of Physiology and Biophysics, The Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neurosci 24:7674-80. 2004
    ..Umami detection involving alpha-gustducin and alpha(t-rod) occurs in anteriorly placed taste buds, however taste cells at the back of the tongue respond to umami compounds independently of these two G-protein subunits...
  4. ncbi Signal transduction of umami taste: insights from knockout mice
    Minqing Rong
    Department of Physiology and Biophysics, Howard Hughes Medical Institute, The Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA
    Chem Senses 30:i33-4. 2005
  5. ncbi Trpm5 null mice respond to bitter, sweet, and umami compounds
    Sami Damak
    Department of Neuroscience, The Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029, USA
    Chem Senses 31:253-64. 2006
    ..Thus, while Trpm5 is an important factor in many taste responses, its absence does not eliminate all taste responses. We conclude that Trpm5-dependent and Trpm5-independent pathways underlie bitter, sweet, and umami tastes...
  6. ncbi Detection of sweet and umami taste in the absence of taste receptor T1r3
    Sami Damak
    Department of Biophysics and Physiology, Mount Sinai School of Medicine, Box 1677, 1425 Madison Avenue, New York, NY 10029, USA
    Science 301:850-3. 2003
    ..These results indicate that T1r3-independent sweet- and umami-responsive receptors and/or pathways exist in taste cells...
  7. ncbi Contribution of alpha-gustducin to taste-guided licking responses of mice
    John I Glendinning
    Department of Biological Science, Barnard College, Columbia University, 3009 Broadway, New York, NY 10027, USA
    Chem Senses 30:299-316. 2005
    ..There was no significant effect of deleting alpha-gustducin on licking responses to NH4Cl or HCl...
  8. ncbi Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin
    Wei He
    Department of Physiology and Biophysics, Howard Hughes Medical Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, NY 10029, USA
    Chem Senses 27:719-27. 2002
    ..Our results also suggest that alpha-transducin and alpha-gustducin may differ, at least in part, in their function in these cells, although this conclusion must be qualified because of the limited fidelity of the transgene expression...