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Genomes and Genes | L WestbergSummaryCountry: Sweden Publications
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Publications
Polymorphisms of the androgen receptor gene and the estrogen receptor beta gene are associated with androgen levels in womenL Westberg
Department of Pharmacology, Goteborg University, SE 405 30 Goteborg, Sweden
J Clin Endocrinol Metab 86:2562-8. 2001..Our results suggest that the serum levels of androgens in premenopausal women may be influenced by variants of the AR gene and the ER beta gene, respectively...- Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteersErik G Jonsson
Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institutet, Stockholm, Sweden
BMC Psychiatry 4:4. 2004..CSF monoamine metabolite concentrations are partly determined by genetic influences... - Association between the estrogen receptor beta gene and age of onset of Parkinson's diseaseL Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Psychoneuroendocrinology 29:993-8. 2004..2 for having an early onset of PD compared to non-carriers. In conclusion, our results indicate that genetic variation in the estrogen receptor beta gene may influence the age of onset of PD... - Polymorphisms in oestrogen and progesterone receptor genes: possible influence on prolactin levels in womenLars Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Clin Endocrinol (Oxf) 61:216-23. 2004.... - Colocalization of connexin 36 and corticotropin-releasing hormone in the mouse brainLars Westberg
Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
BMC Neurosci 10:41. 2009..Here we employ double labeling and retrograde tracing methods to investigate to what extent neuroendocrine and neuropeptide-containing neurons of the hypothalamus and brainstem express the neuronal gap junction protein connexin 36... - Association between a dinucleotide repeat polymorphism of the estrogen receptor alpha gene and personality traits in womenL Westberg
Department of Pharmacology, Goteborg University, Sweden
Mol Psychiatry 8:118-22. 2003..The results suggest that the studied dinucleotide repeat polymorphism of the ER alpha gene may contribute to specific components of personality... - Association between a polymorphism of the 5-HT2C receptor and weight loss in teenage girlsLars Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Neuropsychopharmacology 26:789-93. 2002..The results support the notion that the studied gene may be involved in the regulation of food intake in young women... - Influence of androgen receptor repeat polymorphisms on personality traits in menLars Westberg
Department of Pharmacology, Institute of Neuroscience and Physiology, Gothenburg University, PO Box 431, SE 40530 Gothenburg, Sweden
J Psychiatry Neurosci 34:205-13. 2009..The aim of our study was to investigate the potential influence of 2 functional polymorphisms in the amino terminal of the androgen receptor on personality traits in men... - Serotonin transporter gene polymorphisms and platelet [3H] paroxetine binding in premenstrual dysphoriaJ Melke
Department of Pharmacology, Goteborg University, Sweden
Psychoneuroendocrinology 28:446-58. 2003.... - Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish populationH Niazi Shahabi
Department of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
J Neural Transm 116:567-73. 2009..In conclusion, our results display an association between the rs2070676 polymorphism and PD. Additional investigations are needed to elucidate the importance of this polymorphism for the activity of CYP2E1 and PD susceptibility... - Serotonin transporter gene polymorphisms are associated with anxiety-related personality traits in womenJ Melke
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Am J Med Genet 105:458-63. 2001..In addition, an association was found between the intron 2 polymorphism and one anxiety-related personality trait (somatic anxiety)... - The serotonin reuptake inhibitor fluoxetine reduces sex steroid-related aggression in female rats: an animal model of premenstrual irritability?H P Ho
Department of Pharmacology, , , Sweden
Neuropsychopharmacology 24:502-10. 2001..It is suggested that the aggressive behavior displayed by the female Wistar rat in the resident intruder paradigm may serve as an animal model of premenstrual dysphoria... - Stable serum levels of relaxin throughout the menstrual cycle: a preliminary comparison of women with premenstrual dysphoria and controlsM Pehrsson
Department of Neuroscience and Physiology, Section of Pharmacology, Goteborg University, Goteborg, Sweden
Arch Womens Ment Health 10:147-53. 2007.... - Molecular and neuroanatomical characterization of single neurons in the mouse medullary gigantocellular reticular nucleusE M Martin
Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York 10065, USA
J Comp Neurol 519:2574-93. 2011.... - Association between a functional polymorphism in the progesterone receptor gene and panic disorder in womenHoi Por Ho
Department of Pharmacology, Goteborg University, P O B 431, SE 405 30 Goteborg, Sweden
Psychoneuroendocrinology 29:1138-41. 2004..5. No differences between groups were observed for the PROGINS polymorphism. In conclusion, these data suggest that the G331A polymorphism in the progesterone receptor gene may influence the risk for panic disorder in women... - The lean womanFariba Baghaei
Department of Heart and Lung Diseases, , , Sweden
Obes Res 10:115-21. 2002..The endocrine measurements suggest a well-functioning aromatase, which in turn might have a genetic background, contributing to health. The aromatase gene might be important for regulation of body fat mass... - The CYP19 gene and associations with androgens and abdominal obesity in premenopausal womenFariba Baghaei
The Cardiovascular Institute, Sahlgrenska University Hospital, Goteborg, Sweden
Obes Res 11:578-85. 2003..Polymorphisms of a tetranucleotide repeat [TTTA](n) in the fourth intron of the CYP19 gene are associated with endocrine-dependent diseases and were examined in relation to hormone levels and disease risk factors in premenopausal women... - Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in menKristina Annerbrink
Institute of Neuroscience and Physiology, Goteborg University, and Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, S 405 30 Goteborg, Sweden
Metabolism 57:708-11. 2008.... - Serotonin transporter gene polymorphisms: effect on serotonin transporter availability in the brain of suicide attemptersJessica Bah
Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at Goteborg University, Sweden
Psychiatry Res 162:221-9. 2008..Data suggest that polymorphisms in SLC6A4 may influence the expression of the brain serotonin transporter in suicide attempters... - A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in womenJonas Melke
Departments of Pharmacology, Goteborg University, Goteborg, Sweden
Arch Gen Psychiatry 60:1017-23. 2003..A polymorphism (C178T) in the 5' region of the HTR3A gene has recently been identified and suggested to be of functional importance... - Absence of the Arg441His polymorphism in the tryptophan hydroxylase 2 gene in adults with anxiety disorders and depressionSusanne Henningsson
Am J Med Genet B Neuropsychiatr Genet 144:816-7. 2007 - Cyclooxygenase-2 polymorphisms in Parkinson's diseaseAnna Håkansson
Department of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Am J Med Genet B Neuropsychiatr Genet 144:367-9. 2007..007). In females no difference could be seen between PD-patients and controls. In conclusion, the results suggest a possible influence of the COX-2 C8473T SNP in PD, although it only seems to be of importance in men... - Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in womenSusanne Henningsson
Department of Pharmacology, The Sahlgrenska Academy at Goteborg University, Box 431, SE 405 30 Goteborg, Sweden
Obesity (Silver Spring) 14:1868-73. 2006..None of the associations between IL-6 genotype and lipid pattern seemed to result from an effect of the polymorphism on IL-6 plasma levels... - Catechol O-methyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adultsCindy M de Frias
Department of Psychology, Stockholm University, Stockholm, Sweden
J Cogn Neurosci 17:1018-25. 2005..This COMT polymorphism is a plausible candidate gene for executive functioning and fluid intelligence in nondemented middle-aged and older adults... - Sex steroid-related genes and male-to-female transsexualismSusanne Henningsson
Department of Pharmacology, Institute of Physiology and Pharmacology, , , Sweden
Psychoneuroendocrinology 30:657-64. 2005..Further study of the putative role of these and other sex steroid-related genes for the development of transsexualism may, however, be worthwhile... - Investigation of genes coding for inflammatory components in Parkinson's diseaseAnna Håkansson
Department of Pharmacology, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Mov Disord 20:569-73. 2005..The results indicate that the IL-10 G1082A SNP could possibly be related to the age of onset of PD... - Angiotensin-related genes in patients with panic disorderMarie Olsson
Department of Pharmacology, Goteborg University, Gothenburg, Sweden
Am J Med Genet B Neuropsychiatr Genet 127:81-4. 2004..005), but not female, panic disorder patients than in controls. The results of this investigation provide preliminary evidence for the suggestion that angiotensin-related genes may be associated with panic disorder in men... - COMT gene polymorphism is associated with declarative memory in adulthood and old ageCindy M de Frias
Department of Psychology, Stockholm University, Stockholm, Sweden
Behav Genet 34:533-9. 2004..The COMT gene is a plausible candidate gene for memory functioning in adulthood and old age... - Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson's diseaseAnna Håkansson
Department of Pharmacology, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Am J Med Genet B Neuropsychiatr Genet 133:88-92. 2005..Our results indicate that the G-174C SNP in the IL-6 promoter may influence the risk for developing PD, particularly regarding early age of onset PD, and that the effect is modified by interaction of the G-1730A SNP in the ERbeta gene... - Investigation of transcription factor AP-2 beta genotype in women with premenstrual dysphoric disorderMattias Damberg
Department of Neuroscience, Unit of Pharmacology, Uppsala University, Uppsala, Sweden
Neurosci Lett 377:49-52. 2005..To our knowledge, this is the first study investigating transcription factor AP-2beta genotype in women with PMDD. Hence, these results should be considered preliminary until replicated... - Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humansHasse Walum
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 105:14153-6. 2008..These results suggest an association between a single gene and pair-bonding behavior in humans, and indicate that the well characterized influence of AVP on pair-bonding in voles may be of relevance also for humans...