Research Topics
| Josefine PalleSummaryAffiliation: Uppsala University Country: Sweden Publications
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Detail Information
Publications
Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineageJ Palle
Department of Women s and Children s Health, University Children s Hospital, Uppsala, Sweden
Br J Haematol 129:189-98. 2005..The present study supports the strategy of contemporary protocols to include high-dose cytarabine in the treatment of 11q23-positive patients both in AML and ALL...
Doxorubicin pharmacokinetics is correlated to the effect of induction therapy in children with acute myeloid leukemiaJosefine Palle
Department of Women s and Children s Health, University Children s Hospital, Uppsala, Sweden
Anticancer Drugs 17:385-92. 2006..Prospective studies should be performed to confirm the concentration-effect relationship and explore the possibility of therapeutic monitoring...
Etoposide pharmacokinetics in children treated for acute myeloid leukemiaJosefine Palle
Department of Women s and Children s Health, University Children s Hospital, Uppsala, Sweden
Anticancer Drugs 17:1087-94. 2006..Low course-to-course variability indicates that pharmacokinetically guided dosing of etoposide might be clinically relevant, if larger studies can demonstrate that this approach decreases toxicity or increases response rates...
Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemiaJosefine Palle
Department of Women s and Children s Health, University Children s Hospital, Uppsala, Sweden
Anticancer Drugs 20:7-14. 2009..Children with DS had significantly higher TGN concentrations, indicating that dose reduction might be considered to reach the same drug exposure as in non-DS children...
