Kenneth Nilsson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi Detection and prevalence of Anaplasma phagocytophilum and Rickettsia helvetica in Ixodes ricinus ticks in seven study areas in Sweden
    Kristofer Severinsson
    Department of Medical Sciences, Clinical Bacteriology, Uppsala University, Uppsala, Sweden
    Parasit Vectors 3:66. 2010
  2. ncbi Rickettsia helvetica in patient with meningitis, Sweden, 2006
    Kenneth Nilsson
    Uppsala University Hospital, Uppsala, Sweden
    Emerg Infect Dis 16:490-2. 2010
  3. ncbi Cytotoxic effect in vivo and in vitro of CHS 828 on human myeloma cell lines
    Peter Hovstadius
    Department of Medical Sciences, Division of Clinical Pharmacology, Uppsala University, Uppsala, Sweden
    Anticancer Drugs 15:63-70. 2004
  4. ncbi Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I)
    Helena Jernberg-Wiklund
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Adv Cancer Res 97:139-65. 2007
  5. ncbi Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma
    Marina Tshuikina
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Exp Hematol 36:1673-1681. 2008
  6. ncbi Evidence of Rickettsia spp. infection in Sweden: a clinical, ultrastructural and serological study
    Kenneth Nilsson
    Unit of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    APMIS 113:126-34. 2005
  7. ncbi VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia
    Anna Aleskog
    Department of Internal Medicine, Uppsala University, Uppsala, Sweden
    Eur J Haematol 73:407-11. 2004
  8. ncbi IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways
    Karin Kårehed
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Mol Immunol 44:615-24. 2007
  9. ncbi PML/RARalpha plays a role for basal activity and retinoid-induced repression of the tissue factor promoter in acute promyelocytic leukemia cells
    Taavo Tenno
    Department of Medical Sciences, Clinical Chemistry, Laboratory for Coagulation Research, University Hospital, SE 751 85 Uppsala, Sweden
    Thromb Haemost 90:930-9. 2003
  10. ncbi Life cycle, growth characteristics and host cell response of Rickettsia helvetica in a Vero cell line
    Karin Elfving
    Department of Medical Sciences, Unit of Clinical Bacteriology, Uppsala University, Uppsala, Sweden
    Exp Appl Acarol 56:179-87. 2012

Collaborators

Detail Information

Publications22

  1. ncbi Detection and prevalence of Anaplasma phagocytophilum and Rickettsia helvetica in Ixodes ricinus ticks in seven study areas in Sweden
    Kristofer Severinsson
    Department of Medical Sciences, Clinical Bacteriology, Uppsala University, Uppsala, Sweden
    Parasit Vectors 3:66. 2010
    ..abstract:..
  2. ncbi Rickettsia helvetica in patient with meningitis, Sweden, 2006
    Kenneth Nilsson
    Uppsala University Hospital, Uppsala, Sweden
    Emerg Infect Dis 16:490-2. 2010
    ..Nucleotide sequences of the 16S rRNA, ompB, and 17kDa genes identified the isolate as R. helvetica. This organism may be associated with serious infections such as central nervous system disorders...
  3. ncbi Cytotoxic effect in vivo and in vitro of CHS 828 on human myeloma cell lines
    Peter Hovstadius
    Department of Medical Sciences, Division of Clinical Pharmacology, Uppsala University, Uppsala, Sweden
    Anticancer Drugs 15:63-70. 2004
    ..The results indicate a high cytotoxic activity of CHS 828. Overall, the results show a high cytotoxic activity of CHS 828 in the myeloma models, which might warrant its further development against myeloma...
  4. ncbi Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I)
    Helena Jernberg-Wiklund
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Adv Cancer Res 97:139-65. 2007
    ....
  5. ncbi Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma
    Marina Tshuikina
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Exp Hematol 36:1673-1681. 2008
    ..The objective of this study was to investigate expression of the interferon regulatory factor family (IRF1-9) and the potential role of DNA methylation in silencing IRF genes in MM cell lines and purified MM cells from patients...
  6. ncbi Evidence of Rickettsia spp. infection in Sweden: a clinical, ultrastructural and serological study
    Kenneth Nilsson
    Unit of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    APMIS 113:126-34. 2005
    ..The results of this study demonstrate that spotted fever rickettsioses should be taken into consideration in the diagnosis of tick-transmitted infections in Sweden...
  7. ncbi VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia
    Anna Aleskog
    Department of Internal Medicine, Uppsala University, Uppsala, Sweden
    Eur J Haematol 73:407-11. 2004
    ..The aim of this study was to investigate whether differences in cellular drug resistance could give an explanation for these divergent clinical courses...
  8. ncbi IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways
    Karin Kårehed
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE 751 85 Uppsala, Sweden
    Mol Immunol 44:615-24. 2007
    ..Our results suggest that IFN-gamma-induced increase of FcgammaRI expression requires the integration of two signalling events: PKR-dependent Stat1 serine 727 phosphorylation, and activation of NFkappaB...
  9. ncbi PML/RARalpha plays a role for basal activity and retinoid-induced repression of the tissue factor promoter in acute promyelocytic leukemia cells
    Taavo Tenno
    Department of Medical Sciences, Clinical Chemistry, Laboratory for Coagulation Research, University Hospital, SE 751 85 Uppsala, Sweden
    Thromb Haemost 90:930-9. 2003
    ..These data indicate that TF expression in APL cells is exacerbated by the presence of the PML/RARalpha fusion protein, and implicates the loss of Fos/Jun binding to the TF promoter in ATRA-induced suppression of TF...
  10. ncbi Life cycle, growth characteristics and host cell response of Rickettsia helvetica in a Vero cell line
    Karin Elfving
    Department of Medical Sciences, Unit of Clinical Bacteriology, Uppsala University, Uppsala, Sweden
    Exp Appl Acarol 56:179-87. 2012
    ..The findings differ from what has been reported for other rickettsiae of the spotted fever group and may be of importance for invasiveness and virulence of R. helvetica...
  11. ncbi Dissemination of spotted fever rickettsia agents in Europe by migrating birds
    Karin Elfving
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    PLoS ONE 5:e8572. 2010
    ..In conclusion, migratory passerine birds host epidemiologically important vector ticks and Rickettsia species and contribute to the geographic distribution of spotted fever rickettsial agents and their diseases...
  12. ncbi Rickettsia felis infection in Sweden: report of two cases with subacute meningitis and review of the literature
    A Lindblom
    Unit of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Scand J Infect Dis 42:906-9. 2010
    ..Sequencing of the amplified products showed that they were 99-100% homologous to R. felis. These cases add to our knowledge of the clinical manifestations, as well as the geographical distribution, of this spotted fever agent...
  13. ncbi Positive histone marks are associated with active transcription from a methylated ICSBP/IRF8 gene
    Marina Tshuikina
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden
    Gene 410:259-67. 2008
    ....
  14. ncbi Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells
    Lina Y Dimberg
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Blood 106:1346-54. 2005
    ..Taken together, our results show that IFN-induced up-regulation of Fas sensitizes MM cells to Fas-mediated apoptosis and suggest that attenuation of Stat3 activation may be a potentially important event in this process...
  15. ncbi Development and characterization of two human tumor sublines expressing high-grade resistance to the cyanoguanidine CHS 828
    Joachim Gullbo
    Department of Medical Sciences, Division of Clinical Pharmacology, University Hospital, Uppsala, Sweden
    Anticancer Drugs 15:45-54. 2004
    ..The findings presented here indicate that development of specific cellular alterations is responsible for the gained CHS 828 resistance...
  16. ncbi Presence of Rickettsia helvetica in granulomatous tissue from patients with sarcoidosis
    Kenneth Nilsson
    Section of Infectious Diseases, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    J Infect Dis 185:1128-38. 2002
    ..These results support the hypothesis that rickettsiae may contribute to a granulomatous process, as is seen in sarcoidosis...
  17. ncbi Retinoic acid inhibits in vitro development of mast cells but has no marked effect on mature human skin tryptase- and chymase-positive mast cells
    Malin Hjertson
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    J Invest Dermatol 120:239-45. 2003
    ..Our results suggest that retinoic acid suppresses commitment of progenitor cells into the mast cell lineage and/or acts on early mast cell progenitors, whereas mature cutaneous mast cells are less susceptible to retinoic acid...
  18. ncbi Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1)
    Anna Dimberg
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, S 751 85 Uppsala, Sweden
    Blood 99:2199-206. 2002
    ....
  19. ncbi Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells
    Anna Dimberg
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, S 751 85 Uppsala, Sweden
    Blood 102:254-61. 2003
    ....