Research Topics
| T NaessenSummaryAffiliation: Uppsala University Country: Sweden Publications
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Detail Information
Publications
The expression of syndecan-1, syndecan-4 and decorin in healthy human breast tissue during the menstrual cycleGunilla Hallberg
Department of Women s and Children s Health, Karolinska Institute, Solna S 171 76 Stockholm, Sweden
Reprod Biol Endocrinol 8:35. 2010..The aim of this study was to investigate the gene expression and location of decorin, syndecan-1 and syndecan-4 in the healthy breast during the menstrual cycle...
Menopausal estrogen therapy counteracts normal aging effects on intima thickness, media thickness and intima/media ratio in carotid and femoral arteries. An investigation using noninvasive high-frequency ultrasoundTord Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, University Hospital, SE 751 85 Uppsala, Sweden
Atherosclerosis 189:387-92. 2006..With increased aging and degree of atherosclerosis, the thickness of the artery intima increases and that of the media decreases. These changes can be noninvasively estimated using high-frequency ultrasound...
Early postmenopausal hormone therapy improves postural balanceTord Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, University Hospital, Uppsala, Sweden
Menopause 14:14-9. 2007..We studied the effects of postmenopausal HT on the postural balance of postmenopausal women, with further assessment according to the time since they achieved menopause...
Hormone therapy and postural balance in elderly womenTord Naessen
Department of Women s and Children s Health, Section of Obstetrics and Gynecology, University Hospital, SE 751 85, Uppsala, Sweden
Menopause 14:1020-4. 2007..It is unclear whether hormone therapy (HT) can improve postural balance when initiated in elderly women and the effect of endogenous estradiol (E2) levels...
Tibolone low dose (1.25 mg/d) therapy and postural balance in elderly womenTord Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, University Hospital, SE 751 85 Uppsala, Sweden
Maturitas 62:72-5. 2009..It is unclear whether tibolone improves postural balance, which might determine its effects on peripheral fracture risk...
Steroid profiles in ovarian follicular fluid in women with and without polycystic ovary syndrome, analyzed by liquid chromatography-tandem mass spectrometryTord Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden
Fertil Steril 94:2228-33. 2010..Polycystic ovary syndrome involves abnormal regulation of the steroidogenic enzymes, leading to arrest of follicle development...
Serum lipid profile improved by ultra-low doses of 17 beta-estradiol in elderly womenT Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, University Hospital, SE 751 85 Uppsala, Sweden
J Clin Endocrinol Metab 86:2757-62. 2001..The reduction in LDL cholesterol tended to be greater with a combination of high age and low baseline levels of biologically active estrogens...
Carotid vascular resistance in long-term estrogen usersT Naessen
Department of Women s and Children s Health, Section of Obstetrics and Gynecology, University Hospital, Uppsala, Sweden
Obstet Gynecol 97:327-32. 2001..To compare carotid vascular resistance in long-term estrogen users with that of age-matched nonusers...
Ultrasonographic blood flow measurement in the carotid arteries in postmenopausal womenE Darj
Department of Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden
Gynecol Obstet Invest 47:20-5. 1999..Blood flow was ultrasonographically measured in the great arteries of the neck instead of in the vessels of the internal genital organs...
Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasoundD Leonard
Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden
Scand J Rheumatol 40:279-82. 2011....
Endogenous steroids measured by high-specificity liquid chromatography-tandem mass spectrometry and prevalent cardiovascular disease in 70-year-old men and womenTord Naessen
Department of Women s and Children s Health, Section for Obstetrics and Gynecology, University Hospital, Uppsala SE 751 85, Sweden
J Clin Endocrinol Metab 95:1889-97. 2010..There is a need for increased knowledge about endogenous sex hormone levels and clinical outcomes of risk/benefit. Immunoassays have poor specificity to reliably measure low steroid concentrations in elderly...
Thicker carotid intima layer and thinner media layer in subjects with cardiovascular diseases. An investigation using noninvasive high-frequency ultrasoundKenny A Rodriguez-Macias
Department of Women's and Children's Health, Section for Obstetrics and Gynecology, University Hospital, Uppsala SE-751 85, Sweden
Atherosclerosis 189:393-400. 2006....
Arterial stiffness is not improved in long-term use of estrogenKenny A Rodriguez-Macias
Departments of Women's and Children's Health, Section for Obstetrics and Gynecology, University Hospital, Uppsala, Sweden
Am J Obstet Gynecol 186:189-94. 2002..CONCLUSION: These data indicate that the arterial stiffening that is related to aging/menopause is not substantially affected by long-term estrogen therapy...
Validation of in vivo noninvasive high-frequency ultrasonography of the arterial wall layersK A Rodriguez-Macias
Department of Women s and Children s Health, Section for Obstetrics and Gynaecology, University Hospital, Uppsala, Sweden
Ultrasound Med Biol 27:751-6. 2001..69; p =.01) and media layer (r(s) = 0.76; p =.004). The method seems to give valid estimates of both total arterial wall and media thickness in superficial arteries, but to be less accurate for estimate the adventitia and intima layers...
An open, randomized, controlled study of transdermal hormone replacement therapy on the rate of bone loss in primary biliary cirrhosisS Ormarsdottir
Internal Medicine, Institution for Medical Sciences, University Hospital, Uppsala, Sweden
J Intern Med 256:63-9. 2004..Dual-energy X-ray absorptiometry for measurement of bone mineral density (BMD) and sampling of blood and serum for measurements of biochemical markers of liver function was performed before, during and at the end of treatment...
Ambulatory morning growth hormone concentrations increase in men and decrease in women with ageB Edén Engström
Department of Medical Sciences, University Hospital, Uppsala, Sweden
Scand J Clin Lab Invest 62:25-31. 2002....
Endometrial thickness and uterine diameter not affected by ultralow doses of 17beta-estradiol in elderly womenTord Naessen
Department of Women's and Children's Health, Section of Obstetrics and Gynecology, University Hospital, Uppsala, Sweden
Am J Obstet Gynecol 186:944-7. 2002..This might indicate that there is a "therapeutic window" for systemic effects of ultralow doses of estradiol in elderly women without any apparent increase in endometrial thickness...
Granulosa cell aromatase enzyme activity: effects of follicular fluid from patients with polycystic ovary syndrome, using aromatase conversion and [11C]vorozole-binding assaysDmitrijus Kirilovas
Department of Women's and Children's Health, Section for Obstetrics and Gynecology, University Hospital, Uppsala, Sweden
Gynecol Endocrinol 22:685-91. 2006..Identification of specific agents responsible for this rapid regulation of aromatase function might help to understand normal regulation of the menstrual cycle and supposed imbalances of inhibitors/activators in PCOS...
Thicker carotid intima layer, thinner media layer and higher intima/media ratio in women with recurrent depressive disorders: A pilot study using non-invasive high frequency ultrasoundHannes Bohman
Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden
World J Biol Psychiatry 11:71-5. 2010..Thus, the aim of the present study has been to investigate if young women with adolescent onset and recurrent depressive disorders have signs of carotid intima and media changes already at the age of 30...
Characterization of [11C]vorozole binding in ovarian tissue in rats throughout estrous cycle in association with conversion of androgens to estrogens in vivo and in vitroDmitrijus Kirilovas
Department of Women's and Children's Health, Section for Obstetrics and Gynecology, University Hospital, SE-751 85 Uppsala, Sweden
Steroids 68:1139-46. 2003..The [11C]vorozole in vivo technique keeps auto- and paracrine mechanisms intact, and might therefore yield additional information about biological processes compared with traditional in vitro techniques...
