Research Topics
Species | Tanja LövgrenSummaryAffiliation: Uppsala University Country: Sweden Publications
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Detail Information
Publications
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgGTanja Lövgren
Immunology V, Biomedical Center, Uppsala University, Uppsala, Sweden
Arthritis Rheum 50:1861-72. 2004....
Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNATanja Lövgren
Uppsala University, Uppsala, Sweden
Arthritis Rheum 54:1917-27. 2006..To investigate the ability of systemic lupus erythematosus (SLE) autoantigen- and Sjögren's syndrome (SS) autoantigen-associated U1 small nuclear RNA (U1 snRNA) and hY1RNA to induce interferon-alpha (IFNalpha) production...
Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cellsMaija Leena Eloranta
Department of Medical Sciences, Uppsala University Hospital, and Uppsala University, Uppsala, Sweden
Arthritis Rheum 60:2418-27. 2009..We undertook this study to investigate how IFNalpha production induced by RNA-containing immune complexes (ICs) in plasmacytoid dendritic cells (PDCs) is regulated...
Type I interferon system activation and association with disease manifestations in systemic sclerosisMaija Leena Eloranta
Department of Medical Sciences, Clinical Research Department 3, Systemic Autoimmunity Group, Entrance 85, 3rd Floor, Uppsala University Hospital, Uppsala S 75185, Sweden
Ann Rheum Dis 69:1396-402. 2010..To study the presence of interferogenic autoantibodies in systemic sclerosis (SSc) and their correlation with clinical manifestations, serum levels of interferon alpha (IFNalpha) and chemokines of importance in the disease process...
Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic indexKefei Hu
Department of Medical Sciences, Section of Virology, Uppsala University, Uppsala, Sweden
Int J Nanomedicine 5:51-62. 2010..The nontoxic BBE blocked the cell killing effect of KGI in a concentration-dependent manner. In conclusion, the formulation of QS into nanoparticles has the potential of becoming a new class of anticancer agents...
