Christian Wegener

Summary

Affiliation: Stockholm University
Country: Sweden

Publications

  1. ncbi The periviscerokinin (PVK) peptide family in insects: evidence for the inclusion of CAP(2b) as a PVK family member
    Christian Wegener
    Institut für Allgemeine Zoologie und Tierphysiologie, Friedrich Schiller Universitat, Erbertstr 1, D 07743, Jena, Germany
    Peptides 23:605-11. 2002
  2. ncbi A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions
    Dick R Nassel
    Department of Zoology, Stockholm University, S 10691 Stockholm, Sweden
    BMC Neurosci 9:90. 2008
  3. ncbi Neurotransmitter-induced changes in the intracellular calcium concentration suggest a differential central modulation of CCAP neuron subsets in Drosophila
    Matthias Vömel
    Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Karl von Frisch Strasse, Marburg D 35032, Germany
    Dev Neurobiol 67:792-808. 2007
  4. ncbi Direct peptide profiling of lateral cell groups of the antennal lobes of Manduca sexta reveals specific composition and changes in neuropeptide expression during development
    Sandra Utz
    Fachbereich Biologie, Tierphysiologie, Philipps Universitat, Marburg, Germany
    Dev Neurobiol 67:764-77. 2007
  5. ncbi Neuroarchitecture of aminergic systems in the larval ventral ganglion of Drosophila melanogaster
    Matthias Vömel
    Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Marburg, Germany
    PLoS ONE 3:e1848. 2008
  6. ncbi A simple purification protocol for the detection of peptide hormones in the hemolymph of individual insects by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    Sandy Fastner
    Emmy Noether Neuropeptidgruppe, FB Biologie, Tierphysiologie, Philipps Universitat, Karl von Frisch Strasse, D 35032 Marburg, Germany
    Rapid Commun Mass Spectrom 21:23-8. 2007
  7. ncbi Morphology and metamorphosis of the peptidergic Va neurons and the median nerve system of the fruit fly, Drosophila melanogaster
    Jonathan G Santos
    Emmy Noether Neuropeptide Group, Department of Biology, Animal Physiology, Philipps University, Karl-von-Frisch-Strasse, 35032, Marburg, Germany
    Cell Tissue Res 326:187-99. 2006
  8. ncbi Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites in Drosophila melanogaster reveals tagma-specific peptide expression and differential processing
    Christian Wegener
    Emmy Noether Neuropeptide Group, Animal Physiology, Philipps-University, Marburg, Germany
    J Neurochem 96:1362-74. 2006
  9. ncbi GABA modulates Drosophila circadian clock neurons via GABAB receptors and decreases in calcium
    Yasutaka Hamasaka
    Department of Zoology, Stockholm University, SE 10691, Sweden
    J Neurobiol 65:225-40. 2005
  10. ncbi Peptidomics of CNS-associated neurohemal systems of adult Drosophila melanogaster: a mass spectrometric survey of peptides from individual flies
    Reinhard Predel
    Saxon Academy of Sciences, Research Group Jena, 07743 Jena, Germany
    J Comp Neurol 474:379-92. 2004

Collaborators

Detail Information

Publications12

  1. ncbi The periviscerokinin (PVK) peptide family in insects: evidence for the inclusion of CAP(2b) as a PVK family member
    Christian Wegener
    Institut für Allgemeine Zoologie und Tierphysiologie, Friedrich Schiller Universitat, Erbertstr 1, D 07743, Jena, Germany
    Peptides 23:605-11. 2002
    ..In this review, we provide support for grouping CAP(2b) as a PVK family member based on published sequences, and new immunocytochemical findings and mass spectrometric data...
  2. ncbi A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions
    Dick R Nassel
    Department of Zoology, Stockholm University, S 10691 Stockholm, Sweden
    BMC Neurosci 9:90. 2008
    ..To unravel possible functional diversity we have mapped the distribution of transcript of the snpf gene and its peptide products in the central nervous system (CNS) of Drosophila in relation to other neuronal markers...
  3. ncbi Neurotransmitter-induced changes in the intracellular calcium concentration suggest a differential central modulation of CCAP neuron subsets in Drosophila
    Matthias Vömel
    Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Karl von Frisch Strasse, Marburg D 35032, Germany
    Dev Neurobiol 67:792-808. 2007
    ..Our results suggest that N(CCAP) express functional receptors for ACh, glutamate, and GABA, and indicate that these transmitters are involved in a context-dependent regulation of functionally distinct N(CCAP) subsets...
  4. ncbi Direct peptide profiling of lateral cell groups of the antennal lobes of Manduca sexta reveals specific composition and changes in neuropeptide expression during development
    Sandra Utz
    Fachbereich Biologie, Tierphysiologie, Philipps Universitat, Marburg, Germany
    Dev Neurobiol 67:764-77. 2007
    ..The identification of neuropeptides in the antennal lobes now allows to specifically address the function of these signaling molecules during the formation of the antennal lobe network...
  5. ncbi Neuroarchitecture of aminergic systems in the larval ventral ganglion of Drosophila melanogaster
    Matthias Vömel
    Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Marburg, Germany
    PLoS ONE 3:e1848. 2008
    ....
  6. ncbi A simple purification protocol for the detection of peptide hormones in the hemolymph of individual insects by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    Sandy Fastner
    Emmy Noether Neuropeptidgruppe, FB Biologie, Tierphysiologie, Philipps Universitat, Karl von Frisch Strasse, D 35032 Marburg, Germany
    Rapid Commun Mass Spectrom 21:23-8. 2007
    ..Since this method is simple, relatively cheap and fast, it should be useful for routine endocrinological analyses and for monitoring peptide release during different physiological conditions and behaviors in insects...
  7. ncbi Morphology and metamorphosis of the peptidergic Va neurons and the median nerve system of the fruit fly, Drosophila melanogaster
    Jonathan G Santos
    Emmy Noether Neuropeptide Group, Department of Biology, Animal Physiology, Philipps University, Karl-von-Frisch-Strasse, 35032, Marburg, Germany
    Cell Tissue Res 326:187-99. 2006
    ..Hence, the transverse nerves may serve a neurohaemal function in D. melanogaster...
  8. ncbi Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites in Drosophila melanogaster reveals tagma-specific peptide expression and differential processing
    Christian Wegener
    Emmy Noether Neuropeptide Group, Animal Physiology, Philipps-University, Marburg, Germany
    J Neurochem 96:1362-74. 2006
    ..Our results show that the peptidome of the neurohaemal organs is tagma-specific and does not change during metamorphosis. We also provide evidence for the first case of differential prohormone processing in Drosophila...
  9. ncbi GABA modulates Drosophila circadian clock neurons via GABAB receptors and decreases in calcium
    Yasutaka Hamasaka
    Department of Zoology, Stockholm University, SE 10691, Sweden
    J Neurobiol 65:225-40. 2005
    ..Our results suggest that the s-LN(v)s receive slow inhibitory GABAergic inputs that decrease intracellular calcium of these clock neurons and block their calcium cycling. This response is mediated by postsynaptic GABA(B) receptors...
  10. ncbi Peptidomics of CNS-associated neurohemal systems of adult Drosophila melanogaster: a mass spectrometric survey of peptides from individual flies
    Reinhard Predel
    Saxon Academy of Sciences, Research Group Jena, 07743 Jena, Germany
    J Comp Neurol 474:379-92. 2004
    ....
  11. ncbi Acetylcholine increases intracellular Ca2+ via nicotinic receptors in cultured PDF-containing clock neurons of Drosophila
    Christian Wegener
    Department of Zoology, Stockholm University, SE-10691 Stockholm, Sweden
    J Neurophysiol 91:912-23. 2004
    ..Experiments using a more general GAL4-UAS-driven expression of GFP showed that functional expression of nAChRs is a widespread phenomenon in peptidergic neurons...
  12. ncbi Comparative neuroanatomy and genomics of hugin and pheromone biosynthesis activating neuropeptide (PBAN)
    Rüdiger Bader
    Institut fur Genetik, Forschungszentrum Karlsruhe, Karlsruhe, Germany
    Fly (Austin) 1:228-31. 2007
    ..One concerns the polarity of hugin neurons. The other is an evolutionary perspective on the processing of hugin neuropeptides in light of new data from mass spectrometric and genomic analyses...