Research Topics
Species | Christian WegenerSummaryAffiliation: Stockholm University Country: Sweden Publications
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Publications
The periviscerokinin (PVK) peptide family in insects: evidence for the inclusion of CAP(2b) as a PVK family memberChristian Wegener
Institut für Allgemeine Zoologie und Tierphysiologie, Friedrich Schiller Universitat, Erbertstr 1, D 07743, Jena, Germany
Peptides 23:605-11. 2002..In this review, we provide support for grouping CAP(2b) as a PVK family member based on published sequences, and new immunocytochemical findings and mass spectrometric data...
A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functionsDick R Nassel
Department of Zoology, Stockholm University, S 10691 Stockholm, Sweden
BMC Neurosci 9:90. 2008..To unravel possible functional diversity we have mapped the distribution of transcript of the snpf gene and its peptide products in the central nervous system (CNS) of Drosophila in relation to other neuronal markers...
Neurotransmitter-induced changes in the intracellular calcium concentration suggest a differential central modulation of CCAP neuron subsets in DrosophilaMatthias Vömel
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Karl von Frisch Strasse, Marburg D 35032, Germany
Dev Neurobiol 67:792-808. 2007..Our results suggest that N(CCAP) express functional receptors for ACh, glutamate, and GABA, and indicate that these transmitters are involved in a context-dependent regulation of functionally distinct N(CCAP) subsets...
Direct peptide profiling of lateral cell groups of the antennal lobes of Manduca sexta reveals specific composition and changes in neuropeptide expression during developmentSandra Utz
Fachbereich Biologie, Tierphysiologie, Philipps Universitat, Marburg, Germany
Dev Neurobiol 67:764-77. 2007..The identification of neuropeptides in the antennal lobes now allows to specifically address the function of these signaling molecules during the formation of the antennal lobe network...
Neuroarchitecture of aminergic systems in the larval ventral ganglion of Drosophila melanogasterMatthias Vömel
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Marburg, Germany
PLoS ONE 3:e1848. 2008....
A simple purification protocol for the detection of peptide hormones in the hemolymph of individual insects by matrix-assisted laser desorption/ionization time-of-flight mass spectrometrySandy Fastner
Emmy Noether Neuropeptidgruppe, FB Biologie, Tierphysiologie, Philipps Universitat, Karl von Frisch Strasse, D 35032 Marburg, Germany
Rapid Commun Mass Spectrom 21:23-8. 2007..Since this method is simple, relatively cheap and fast, it should be useful for routine endocrinological analyses and for monitoring peptide release during different physiological conditions and behaviors in insects...
Morphology and metamorphosis of the peptidergic Va neurons and the median nerve system of the fruit fly, Drosophila melanogasterJonathan G Santos
Emmy Noether Neuropeptide Group, Department of Biology, Animal Physiology, Philipps University, Karl-von-Frisch-Strasse, 35032, Marburg, Germany
Cell Tissue Res 326:187-99. 2006..Hence, the transverse nerves may serve a neurohaemal function in D. melanogaster...
Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites in Drosophila melanogaster reveals tagma-specific peptide expression and differential processingChristian Wegener
Emmy Noether Neuropeptide Group, Animal Physiology, Philipps-University, Marburg, Germany
J Neurochem 96:1362-74. 2006..Our results show that the peptidome of the neurohaemal organs is tagma-specific and does not change during metamorphosis. We also provide evidence for the first case of differential prohormone processing in Drosophila...
GABA modulates Drosophila circadian clock neurons via GABAB receptors and decreases in calciumYasutaka Hamasaka
Department of Zoology, Stockholm University, SE 10691, Sweden
J Neurobiol 65:225-40. 2005..Our results suggest that the s-LN(v)s receive slow inhibitory GABAergic inputs that decrease intracellular calcium of these clock neurons and block their calcium cycling. This response is mediated by postsynaptic GABA(B) receptors...
Peptidomics of CNS-associated neurohemal systems of adult Drosophila melanogaster: a mass spectrometric survey of peptides from individual fliesReinhard Predel
Saxon Academy of Sciences, Research Group Jena, 07743 Jena, Germany
J Comp Neurol 474:379-92. 2004....
Acetylcholine increases intracellular Ca2+ via nicotinic receptors in cultured PDF-containing clock neurons of DrosophilaChristian Wegener
Department of Zoology, Stockholm University, SE-10691 Stockholm, Sweden
J Neurophysiol 91:912-23. 2004..Experiments using a more general GAL4-UAS-driven expression of GFP showed that functional expression of nAChRs is a widespread phenomenon in peptidergic neurons...
Comparative neuroanatomy and genomics of hugin and pheromone biosynthesis activating neuropeptide (PBAN)Rüdiger Bader
Institut fur Genetik, Forschungszentrum Karlsruhe, Karlsruhe, Germany
Fly (Austin) 1:228-31. 2007..One concerns the polarity of hugin neurons. The other is an evolutionary perspective on the processing of hugin neuropeptides in light of new data from mass spectrometric and genomic analyses...
