Research Topics
Genomes and Genes | T DeierborgSummaryAffiliation: Lund University Country: Sweden Publications
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Publications
Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after strokeAna R Inácio
Laboratory for Experimental Brain Research, Department of Clinical Sciences, Lund University, BMC A13, 22184 Lund, Sweden
J Neuroinflammation 8:75. 2011..Since MIF regulates tissue inflammation, we studied the putative role of MIF in post-stroke inflammation...
Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouseTomas Deierborg
Laboratory for Experimental Brain Research, Wallenberg Neuroscience Center, Lund University BMC A13, Lund, Sweden
J Cereb Blood Flow Metab 28:1186-95. 2008..Consequently, neuroprotection in the thalamus correlated with a high expression of UCP2, which is neuroprotective in a number of models of neurodegenerative diseases...
Emerging restorative treatments for Parkinson's diseaseTomas Deierborg
Neuronal Survival Unit, BMC A10, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden
Prog Neurobiol 85:407-32. 2008..e. neural and embryonic stem cells, to differentiate into dopaminergic neurons. Finally, we discuss adult neurogenesis as a potential tool for restoring lost dopamine neurons in patients suffering from Parkinson's disease...
Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuriesTomas Deierborg
Neuronal Survival Unit, BMC A10, Dept of Experimental Medical Science, Wallenberg Neuroscience Center, 221 84 Lund, Sweden
Exp Neurol 219:363-7. 2009..Our study demonstrates that both the time window for labeling proliferating cells and the site of lesion are crucial when assessing neurogenesis following brain injury...
Brain injury activates microglia that induce neural stem cell proliferation ex vivo and promote differentiation of neurosphere-derived cells into neurons and oligodendrocytesT Deierborg
Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, BMC A10, 22184 Lund, Sweden
Neuroscience 171:1386-96. 2010....
Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatumJosefine Nygren
Experimental Brain Research, Wallenberg Neuroscience Center, Lund University, Lund, Sweden
Stroke 37:2824-9. 2006..CONCLUSIONS: An enriched environment after experimental stroke increased neurogenesis in the hippocampus, whereas there was a decreased cell genesis and migration of neuroblasts and newborn astrocytes in the striatum...
Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: influence of enriched environmentMattias Rickhag
Laboratory for Experimental Brain Research, Wallenberg Neuroscience Center, University of Lund, Lund, Sweden
J Cereb Blood Flow Metab 28:551-62. 2008..Our data strongly suggest that apoD is involved in regenerative processes and scar formation in the peri-infarct area presumably by enhancing lipid trafficking...
Increased metabolism in the R6/2 mouse model of Huntington's diseaseJorien M M van der Burg
Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University BMC A10, Lund, Sweden
Neurobiol Dis 29:41-51. 2008..Together, these data demonstrate that weight loss in R6/2 mice is associated with increased metabolism and changes in several weight-regulating factors...
Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesisLaurent Roybon
Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, BMC A10, 22184 Lund, Sweden
Eur J Neurosci 29:232-43. 2009..Taken together, our data illustrate that Ngn2, neuroD and Tbr transcription factors are involved in postnatal neurogenesis in the olfactory bulb...
