Research Topics
| J WahrenSummaryAffiliation: Karolinska Hospital Country: Sweden Publications
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Detail Information
Publications
Role of C-peptide in human physiologyJ Wahren
Department of Surgical Sciences, Section of Clinical Physiology, Karolinska Hospital, SE 171 76 Stockholm, Sweden
Am J Physiol Endocrinol Metab 278:E759-68. 2000..The possibility exists that C-peptide replacement, together with insulin administration, may prevent the development or retard the progression of long-term complications in type 1 diabetes...
C-peptide: a new potential in the treatment of diabetic nephropathyJ Wahren
Department of Surgical Sciences, Karolinska Hospital, Stockholm SE 171 76, Sweden
Curr Diab Rep 1:261-6. 2001..C-peptide replacement together with insulin therapy may be beneficial in type 1 diabetes patients with nephropathy...
C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cellsZ Zhong
Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institute, Stockholm, Sweden
Diabetologia 48:187-97. 2005....
Insulin binding monitored by fluorescence correlation spectroscopyZ H Zhong
Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
Diabetologia 44:1184-8. 2001..Because of its high sensitivity (single molecule detection), FCS, provides additional data allowing a more precise evaluation of the kinetics of ligand-receptor interactions at low expression levels in living cells...
Ernst-Friedrich-Pfeiffer Memorial Lecture. New aspects of C-peptide physiologyJ Wahren
Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
Horm Metab Res 30:A2-5. 1998..In conclusion, the combined findings indicate that C-peptide is a biologically active hormone. The possibility that C-peptide therapy in IDDM patients may be beneficial should be considered...
C-peptide is a bioactive peptideJ Wahren
Department of Molecular Medicine and Surgery, Karolinska Hospital, 171 76, Stockholm, Sweden
Diabetologia 50:503-9. 2007
Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunctionA Katz
Department of Surgical Sciences, Division of Clinical Physiology, Karolinska Institute, Karolinska Hospital, 171 76 Stockholm, Sweden
Clin Sci (Lond) 101:59-64. 2001..These data demonstrate that Type I diabetic patients have similar diminished SBF responses to iontophoresis of ACh and SNP, which suggests that non-endothelial-dependent factors are primarily responsible for the diminished SBF responses...
Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fastingK Ekberg
Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden
Diabetes 48:292-8. 1999....
C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cellsZ Zhong
Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institutet, 17177 Stockholm, Sweden
Cell Mol Life Sci 61:2782-90. 2004..In conclusion, C-peptide stimulates sodium pump activity via ERK1/2-induced phosphorylation of Thr residues on the alpha subunit of Na(+), K(+)-ATPase...
Long-term use of smokeless tobacco and physical performance in middle-aged menG Bolinder
Department of Medicine, Karolinska Hospital, Stockholm, Sweden
Eur J Clin Invest 27:427-33. 1997..001). The findings indicate that long-term use of smokeless tobacco does not significantly influence exercise capacity in healthy, physically well-trained subjects...
