J Wahren

Summary

Affiliation: Karolinska Hospital
Country: Sweden

Publications

  1. ncbi Role of C-peptide in human physiology
    J Wahren
    Department of Surgical Sciences, Section of Clinical Physiology, Karolinska Hospital, SE 171 76 Stockholm, Sweden
    Am J Physiol Endocrinol Metab 278:E759-68. 2000
  2. ncbi C-peptide: a new potential in the treatment of diabetic nephropathy
    J Wahren
    Department of Surgical Sciences, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Curr Diab Rep 1:261-6. 2001
  3. ncbi C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells
    Z Zhong
    Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institute, Stockholm, Sweden
    Diabetologia 48:187-97. 2005
  4. ncbi Insulin binding monitored by fluorescence correlation spectroscopy
    Z H Zhong
    Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
    Diabetologia 44:1184-8. 2001
  5. ncbi Ernst-Friedrich-Pfeiffer Memorial Lecture. New aspects of C-peptide physiology
    J Wahren
    Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
    Horm Metab Res 30:A2-5. 1998
  6. ncbi C-peptide is a bioactive peptide
    J Wahren
    Department of Molecular Medicine and Surgery, Karolinska Hospital, 171 76, Stockholm, Sweden
    Diabetologia 50:503-9. 2007
  7. ncbi Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction
    A Katz
    Department of Surgical Sciences, Division of Clinical Physiology, Karolinska Institute, Karolinska Hospital, 171 76 Stockholm, Sweden
    Clin Sci (Lond) 101:59-64. 2001
  8. ncbi Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting
    K Ekberg
    Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden
    Diabetes 48:292-8. 1999
  9. ncbi C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells
    Z Zhong
    Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institutet, 17177 Stockholm, Sweden
    Cell Mol Life Sci 61:2782-90. 2004
  10. ncbi Long-term use of smokeless tobacco and physical performance in middle-aged men
    G Bolinder
    Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    Eur J Clin Invest 27:427-33. 1997

Collaborators

Detail Information

Publications10

  1. ncbi Role of C-peptide in human physiology
    J Wahren
    Department of Surgical Sciences, Section of Clinical Physiology, Karolinska Hospital, SE 171 76 Stockholm, Sweden
    Am J Physiol Endocrinol Metab 278:E759-68. 2000
    ..The possibility exists that C-peptide replacement, together with insulin administration, may prevent the development or retard the progression of long-term complications in type 1 diabetes...
  2. ncbi C-peptide: a new potential in the treatment of diabetic nephropathy
    J Wahren
    Department of Surgical Sciences, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Curr Diab Rep 1:261-6. 2001
    ..C-peptide replacement together with insulin therapy may be beneficial in type 1 diabetes patients with nephropathy...
  3. ncbi C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells
    Z Zhong
    Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institute, Stockholm, Sweden
    Diabetologia 48:187-97. 2005
    ....
  4. ncbi Insulin binding monitored by fluorescence correlation spectroscopy
    Z H Zhong
    Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
    Diabetologia 44:1184-8. 2001
    ..Because of its high sensitivity (single molecule detection), FCS, provides additional data allowing a more precise evaluation of the kinetics of ligand-receptor interactions at low expression levels in living cells...
  5. ncbi Ernst-Friedrich-Pfeiffer Memorial Lecture. New aspects of C-peptide physiology
    J Wahren
    Department of Surgical Sciences, Karolinska Hospital, Stockholm, Sweden
    Horm Metab Res 30:A2-5. 1998
    ..In conclusion, the combined findings indicate that C-peptide is a biologically active hormone. The possibility that C-peptide therapy in IDDM patients may be beneficial should be considered...
  6. ncbi C-peptide is a bioactive peptide
    J Wahren
    Department of Molecular Medicine and Surgery, Karolinska Hospital, 171 76, Stockholm, Sweden
    Diabetologia 50:503-9. 2007
  7. ncbi Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction
    A Katz
    Department of Surgical Sciences, Division of Clinical Physiology, Karolinska Institute, Karolinska Hospital, 171 76 Stockholm, Sweden
    Clin Sci (Lond) 101:59-64. 2001
    ..These data demonstrate that Type I diabetic patients have similar diminished SBF responses to iontophoresis of ACh and SNP, which suggests that non-endothelial-dependent factors are primarily responsible for the diminished SBF responses...
  8. ncbi Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting
    K Ekberg
    Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden
    Diabetes 48:292-8. 1999
    ....
  9. ncbi C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells
    Z Zhong
    Section of Clinical Physiology, Department of Surgical Sciences, Karolinska Institutet, 17177 Stockholm, Sweden
    Cell Mol Life Sci 61:2782-90. 2004
    ..In conclusion, C-peptide stimulates sodium pump activity via ERK1/2-induced phosphorylation of Thr residues on the alpha subunit of Na(+), K(+)-ATPase...
  10. ncbi Long-term use of smokeless tobacco and physical performance in middle-aged men
    G Bolinder
    Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    Eur J Clin Invest 27:427-33. 1997
    ..001). The findings indicate that long-term use of smokeless tobacco does not significantly influence exercise capacity in healthy, physically well-trained subjects...