Research Topics
Species | H KallbergSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunityLina M Olsson
Medical Inflammation Research, Lund University, BMC I11, 221 84, Lund, Sweden
Arthritis Res Ther 9:R98. 2007....- Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smokeHenrik Kallberg
Correspondence to Dr Henrik Källberg, Institute of Environmental Medicine, Box 210, Karolinska Institutet, 171 77 Stockholm, Sweden
Ann Rheum Dis 70:508-11. 2011..Less is known on how smoking contributes to RA in the context of genetic variability, and what proportion of RA may be caused by smoking... - Don't split your dataHenrik Kallberg
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Eur J Epidemiol 25:283-4. 2010..We compare the random splitting procedure to using the full data sample for analysis, by using a Bayesian perspective with consideration taken to prior probability of a false positive finding... - Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritisHenrik Kallberg
Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Am J Hum Genet 80:867-75. 2007..The data extend the basis for a pathogenetic hypothesis for RA involving genetic and environmental factors. The study also raises and illustrates principal questions concerning ways to define interactions in complex diseases... - Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studiesH Kallberg
Institute of Environmental Medicine, Box 210, Karolinska Institutet, 17177 Stockholm, Sweden
Ann Rheum Dis 68:222-7. 2009..To determine the association between risk of rheumatoid arthritis (RA) and alcohol consumption in combination with smoking and HLA-DRB1 shared epitope (SE)... - Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritisEmeli Lundström
Karolinska Institutet, Stockholm, Sweden
Arthritis Rheum 60:924-30. 2009.... - Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA studyP Stolt
Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
Ann Rheum Dis 64:582-6. 2005..To study the association between silica exposure and rheumatoid arthritis and how it is modified by cigarette smoking... - Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritisHiba Mahdi
Rheumatology Unit, Karolinska Institutet, Center for Molecular Medicine, Stockholm, Sweden
Nat Genet 41:1319-24. 2009..We conclude that citrullinated alpha-enolase is a specific citrullinated autoantigen that links smoking to genetic risk factors in the development of RA... - Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritisMaria Seddighzadeh
Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Eur J Hum Genet 18:821-6. 2010..This finding may lead to the development of treatment based on enhancing the protective features of 5-HT2A in individuals with a certain HLA genotype... - Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritisPatrik Stolt
Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
Ann Rheum Dis 69:1072-6. 2010..To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA)... - Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case-control studyBerit Sverdrup
Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
Arthritis Res Ther 7:R1296-303. 2005..The findings are of particular interest since the same mineral oils can induce polyarthritis in rats... - Common vaccinations among adults do not increase the risk of developing rheumatoid arthritis: results from the Swedish EIRA studyCamilla Bengtsson
Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
Ann Rheum Dis 69:1831-3. 2010..To investigate the association between vaccinations in adults and the risk of developing rheumatoid arthritis (RA)... - Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are importantEmeli Lundström
Karolinska Institutet, Rheumatology Unit, Department of Medicine, Stockholm, Sweden
Arthritis Rheum 60:1597-603. 2009..We aimed to further investigate this interaction between distinct SE alleles and smoking regarding the risk of developing RA with and without anti-citrullinated protein antibodies (ACPAs)...