Research Topics
| Bengt IsakssonSummaryAffiliation: Karolinska University Hospital Country: Sweden Publications
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Detail Information
Publications
Continuous assessment of intrahepatic metabolism by microdialysis during and after portal triad clampingBengt Isaksson
Department of Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
J Surg Res 169:214-9. 2011..Our aim was to evaluate the feasibility of microdialysis as a tool to assess the intrahepatic metabolic effects of PTC in patients undergoing liver resection...
Evidence for an important role of CIDEA in human cancer cachexiaJurga Laurencikiene
Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
Cancer Res 68:9247-54. 2008..001). We conclude that CIDEA is involved in adipose tissue loss in cancer cachexia and this may, at least in part, be due to its ability to inactivate PDC, thereby switching substrate oxidation in human fat cells from glucose to FAs...
Bile duct obstruction is associated with early postoperative upregulation of liver uncoupling protein-2 and reduced circulating glucose concentration in the ratLars Enochsson
Division of Surgery, Department for Clinical Science Intervention and Technology CLINTEC, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
Nutrition 26:405-10. 2010..To evaluate whether upregulation of liver and muscle uncoupling protein 2 (UCP-2) is an acute phenomenon in obstructive jaundice and associated with secondary metabolic effects...
Lipolysis--not inflammation, cell death, or lipogenesis--is involved in adipose tissue loss in cancer cachexiaMikael Ryden
Department of Medicine, Karolinska Institute at Karolinska University Hospital, Stockholm, Sweden
Cancer 113:1695-704. 2008..In this study, the authors investigated whether alterations in fat cell numbers, lipogenesis, or cytokine and/or leukocyte infiltration could account for some of the functional changes observed in WAT in cancer cachexia...
Mechanisms for skeletal muscle insulin resistance in patients with pancreatic ductal adenocarcinomaThorhallur Agustsson
Division of Surgery, Department of Clinical Science, Intervention and Technology CLINTEC at Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
Nutrition 27:796-801. 2011..To explore whether PDAC cells could influence muscle glucose uptake, myotubes were exposed to media conditioned by PDAC cells...
The added value of contrast-enhanced ultrasound in patients with colorectal cancer undergoing preoperative evaluation with extensive gadobenate dimeglumine liver MRINikolaos Kartalis
Division of Medical Imaging and Technology, Department of Clinical Science, Intervention and Technology CLINTEC, Karolinska Institutet, Stockholm, Sweden
Eur Radiol 21:2067-73. 2011....
Efficacy of preoperative radiochemotherapy in patients with locally advanced pancreatic carcinomaPehr A Lind
Department of Oncology, Karolinska Stockholm Söder Hospital, Stockholm, Sweden
Acta Oncol 47:413-20. 2008..We treated 17 consecutive cases with preoperative radiochemotherapy (RCT) as a means for downstaging their tumours and compared outcome with 35 patients undergoing direct surgery for primarily resectable PAC during the same time period...
Mechanism of increased lipolysis in cancer cachexiaThorhallur Agustsson
Department of Surgery, Karolinska Institutet at Karolinska University Hospital, Stockhom, Sweden
Cancer Res 67:5531-7. 2007..The selective inhibition of this enzyme may prevent fat loss in cancer patients...
mRNA for pancreatic uncoupling protein 2 increases in two models of acute experimental pancreatitis in rats and miceRalf Segersvard
Division of Surgery, Center for Surgical Sciences, K53, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
Cell Tissue Res 320:251-8. 2005..Therefore, acinar UCP2 may be an important modifier of the severity of acute pancreatitis...
Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patientsBengt Isaksson
Arvid Wretlind Laboratory for Metabolic and Nutritional Research, Department of Surgery, Karolinska Institute at Huddinge University Hospital, Stockholm, Sweden
Pancreas 26:173-7. 2003..This associated metabolic disorder includes peripheral insulin resistance, which may be caused by factors produced by the PC. The mechanism underlying PC-associated insulin resistance has not been clearly defined...
