Research Topics
| Gunnar HillerdalSummaryAffiliation: Karolinska University Hospital Country: Sweden Publications
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Detail Information
Publications
Randomized phase II study of gemcitabine and carboplatin +/- sequential docetaxel in non-small cell lung cancerGunnar Hillerdal
Department of Pulmonary Medicine and Allergy, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
Lung Cancer 71:178-81. 2011..6 and 10.1 months in the GC and GCD groups, respectively. Thus, sequential treatment with docetaxel after treatment with gemcitabine and carboplatin did not improve time to progression, response rates, or overall survival...
Treatment of malignant pleural mesothelioma with liposomized doxorubicine: prolonged time to progression and good survival. A Nordic studyGunnar Hillerdal
Department of Lung Medicine and Allergology, Karolinska University Hospital, Solna, Stockholm, Sweden
Clin Respir J 2:80-5. 2008..Malignant pleural mesothelioma (MPM) has a poor prognosis and there is limited effect of treatment. Lately, pemetrexed and cisplatin have been established as the standard treatment...
Yellow nail syndrome: treatment with octreotideGunnar Hillerdal
Department of Lung Medicine and Allergy Karolinska University Hospital, SE 171 76 Stockholm, Sweden
Clin Respir J 1:120-1. 2007..The pleural effusion in YNS is usually an exudate, but in rare cases a frank chylothorax. One such case with successful octreotide treatment has been described in the literature (5)...
Treatment of malignant pleural mesothelioma with carboplatin, liposomized doxorubicin, and gemcitabine: a phase II studyGunnar Hillerdal
Department of Lung Medicine and Allergology, Karolinska University Hospital, Solna, Stockholm, Sweden
J Thorac Oncol 3:1325-31. 2008..The Nordic Mesothelioma groups decided in the year 2000 to investigate a combination of liposomized doxorubicin, carboplatin, and gemcitabine for this disease in a phase II study...
Indolent lung cancers--time for a paradigm shift: a reviewGunnar Hillerdal
Department of Pulmonary Medicine and Allergy, Karolinska University, Stockholm, Sweden
J Thorac Oncol 3:208-11. 2008..e., whether it is indolent or actually threatens the patient's life, we will be able to give better advice...
Malignant mediastinal tumor with bone formation--mesothelioma or sarcoma?Gunnar Hillerdal
Department of Lung Medicine, Karolinska University Hospital, Stockholm, Sweden
J Thorac Oncol 2:983-4. 2007..This is to our knowledge the first report of a sarcomatous mesothelioma with bone formation from environmental exposure to mineral fibers...
[Emphysema surgery--considerably improved quality of life for a specially selected group of patients. Strict selection criteria are very important]Gunnar Hillerdal
Karolinska Universitetssjukhuset, Stockholm
Lakartidningen 103:3375-6. 2006
Pleuropulmonary lesions, ergotamines and asbestos exposureGunnar Hillerdal
Department of Pulmonary Medicine, Karolinska University Hospital, Stockholm, Sweden
Scand J Work Environ Health 31:459-64. 2005..This study investigated the possibility of pleuropulmonary lesions, which can occur as rare but serious side effects of different ergot drugs, occurring more commonly in persons earlier exposed to asbestos...
Comparison of lung volume reduction surgery and physical training on health status and physiologic outcomes: a randomized controlled clinical trialGunnar Hillerdal
Department of Pulmonary Medicine, Karolinska Hospital, Stockholm, Sweden
Chest 128:3489-99. 2005..The primary end point was health status; secondary end points included survival and physiologic measurements...
Hemoptysis and coughing up of staples as a late complication of volume reduction surgery for emphysemaGunnar Hillerdal
Department of Lung Medicine, Karolinska Hospital, 17176 Stockholm, Sweden
Respir Med 100:371-3. 2006..Possibly, the calf pericardium used as strenghtener of the suture lines will with time cause an immunological reaction, causing destruction of the foreign material and thereby dislodging the staples...
Multicentre phase II trial of paclitaxel and carboplatin with concurrent radiotherapy in locally advanced non-small cell lung cancerRoger Tell
Department of Oncology, Karolinska University Hospital, Stockholm, Sweden
Anticancer Res 28:2851-7. 2008..To evaluate weekly induction chemotherapy followed by weekly concomitant chemoradiotherapy in a multicentre phase II study of patients with unresectable stage III non-small cell lung cancer (NSCLC; stage wet IIIB excluded)...
Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: the Swedish Lung Cancer Study GroupChrister Sederholm
Department of Pulmonary Medicine, Oncologic Center, University Hospital, Linkoping, Sweden
J Clin Oncol 23:8380-8. 2005..Secondary objectives were to compare response, time to progression, toxicity, and quality of life...
Detection of Chlamydia pneumoniae on cytospin preparations from bronchoalveolar lavage in COPD patients and in lung tissue from advanced emphysemaEva Brandén
Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden
Int J Chron Obstruct Pulmon Dis 2:643-50. 2007..In conclusion, the assays used for detection of C. pneumoniae in lung tissue are feasible, and could be adapted in adequately powered studies to further confirm an association between C. pneumoniae infection and COPD...
Staging and evaluating responses in malignant pleural mesotheliomaGunnar Hillerdal
Department of Lung Medicine, Karolinska Hospital, Stockholm, Sweden
Lung Cancer 43:75-6. 2004
The Swedish experience with asbestos: history of use, diseases, legislation, and compensationGunnar Hillerdal
Department of Pulmonary Medicine, Karolinska Hospital, Stockholm, Sweden
Int J Occup Environ Health 10:154-8. 2004..Compensation is from the state via general insurance and consists basically of compensation for lost income and medical costs...
Screening for mesothelioma: more harm than good?Jan P van Meerbeeck
Am J Respir Crit Care Med 178:781-2. 2008
The 'reservoir' of undetected bronchial carcinomas in the general populationHirsh Koyi
Department of Respiratory Medicine, Gävleborg County Hospital, 801 87 Gävle, Sweden
Lung Cancer 37:137-42. 2002..Autopsy studies have shown that a sizeable portion of lung cancers are never diagnosed and thus not entered into any cancer registry...
Imaging, staging and response evaluationMichael Byrne
Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, WA 6009, Australia
Lung Cancer 49:S25-6. 2005
A prospective study of a total material of lung cancer from a county in Sweden 1997-1999: gender, symptoms, type, stage, and smoking habitsHirsh Koyi
Department of Respiratory Medicine, Gaevle County Hospital, S 801 87, Sweden
Lung Cancer 36:9-14. 2002..0% of patients were asymptomatic. In conclusion, the trend of an increasing proportion of adenocarcinoma in lung cancer is seen also in Sweden. A depressingly high percentage of patients present in late stages and are thus inoperable...
Patient's and doctors' delays in the diagnosis of chest tumorsHirsh Koyi
Department of Respiratory Medicine, Gaevle County Hospital, S 80187, Gaevle, Sweden
Lung Cancer 35:53-7. 2002..It is well known that there are delays in diagnosis of lung cancer, both from the patients and from the doctors. We decided to prospectively study this in our area...
Computed tomography features in malignant pleural mesothelioma and other commonly seen pleural diseasesMuzaffer Metintas
Department of Chest Diseases, Osmangazi University Medical Faculty, Eskisehir, Turkey
Eur J Radiol 41:1-9. 2002..To investigate the computed tomography (CT) features of malignant pleural mesothelioma (MPM) cases, comparing them to those in other malignant and benign pleural diseases...
Pleurodesis in recurrent pleural effusions: a randomized comparison of a classical and a currently popular drugValiant Ukale
Department of Medicine, Division of Respiratory Medicine, Thoracic Clinics, Karolinska sjukhuset, S 171 76 Stockholm, Sweden
Lung Cancer 43:323-8. 2004..It was therefore decided to make a prospective randomized clinical study comparing quinacrine (500 mg) with talc (5 g) with regard to efficacy and safety...
Inflammatory parameters after pleurodesis in recurrent malignant pleural effusions and their predictive valueValiant Ukale
Department of Medicine, Thoracic Clinics, Karolinska sjukhuset, Stockholm S 171 76, Sweden
Respir Med 98:1166-72. 2004..High fever and high inflammatory parameters including CRP are due to this inflammatory response and do not indicate infection...
