Research Topics
Genomes and GenesSpecies | Anna FarnertSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
| Collaborators
|
Detail Information
Publications
Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre studyA Farnert
Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Huddinge University Hospital, 14186 Huddinge, Sweden
Trans R Soc Trop Med Hyg 95:225-32. 2001..falciparum but this study has revealed limitations in comparing results on multiplicity of infection derived from different laboratories and emphasizes the need for highly standardized laboratory protocols...
Polyclonal Plasmodium falciparum malaria in travelers and selection of antifolate mutations after proguanil prophylaxisAnna Farnert
Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
Am J Trop Med Hyg 66:487-91. 2002..Chemoprophylaxis reduces the number of infecting clones and selects for resistant parasites as shown for proguanil through mutations in the dhfr gene...
Limited advantage of multiple consecutive samples for genotyping Plasmodium falciparum populations during the first days of treatmentAnna Farnert
Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Am J Trop Med Hyg 73:204-6. 2005..The genotypes detected in one pre-treatment sample thus appear to reflect the parasite subpopulations of the clinical malaria infection during the following days, and additional sampling does not provide any additional information...
Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in TanzaniaAndreas Martensson
Infectious Diseases Unit, Department of Medicine, Karolinska University Hospital, Stockholm 17176, Sweden
J Infect Dis 195:597-601. 2007..Interpretation of PCR-adjusted results will significantly depend on methodology...
Optimization and validation of multi-coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2)Anne Liljander
Department of Medicine Solna, Karolinska Institutet, SE 171 76 Stockholm, Sweden
Malar J 8:78. 2009..falciparum msp1 and msp2 has been adapted to the CE technique. The protocol and optimization process as well as the potentials and limitations of the technique in molecular epidemiology studies and anti-malarial drug trials are reported...
Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profilesAnna Farnert
Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Malar J 7:241. 2008..The aim of this study was to assess the dynamics of asymptomatic P. falciparum infections in a few hours intervals...
Multiclonal asymptomatic Plasmodium falciparum infections predict a reduced risk of malaria disease in a Tanzanian populationSandor Bereczky
Infectious Diseases Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital Solna, 17176 Stockholm, Sweden
Microbes Infect 9:103-10. 2007....
Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in AfricaSabina Dahlström
Malaria Research, Karolinska Institutet, Stockholm, Sweden
J Infect Dis 200:1456-64. 2009..Our data suggest for the first time, to our knowledge, the involvement of pfMRP1 in P. falciparum in vivo response to ACT...
Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria riskAnne Liljander
Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
PLoS ONE 5:e13649. 2010..We have investigated how seasonal IPT affects the genetic diversity of Plasmodium falciparum infections and the risk of subsequent clinical malaria...
Short report: Rapid DNA extraction from archive blood spots on filter paper for genotyping of Plasmodium falciparumSandor Bereczky
Infectious Diseases Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Am J Trop Med Hyg 72:249-51. 2005..This rapid, simple, and inexpensive extraction method generated superior results from archived specimens compared with the two standard methods and may represent a useful tool in molecular epidemiologic studies...
Transmission-dependent tolerance to multiclonal Plasmodium falciparum infectionAnna Farnert
Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
J Infect Dis 200:1166-75. 2009..falciparum infections...
High-speed shaking of frozen blood clots for extraction of human and malaria parasite DNAKlara Lundblom
Infectious Diseases Unit, Karolinska Institutet, Center for Molecular Medicine, L8 01, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
Malar J 10:229. 2011..Frozen blood clots remaining after serum collection is an often disregarded source of host and pathogen DNA due to troublesome handling and suboptimal outcome...
Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan childrenAnne Liljander
Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
PLoS ONE 6:e16940. 2011..Asymptomatic multiclonal P. falciparum infections are common and may predict host protection. Here, we have investigated the effect of clearing asymptomatic infections on the risk of clinical malaria...
Plasmodium falciparum population dynamics: only snapshots in time?Anna Farnert
Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, SE 17176 Stockholm, Sweden
Trends Parasitol 24:340-4. 2008..falciparum infections have practical implications on the design and interpretation of malaria studies. Most assessments will, indeed, only provide snapshots of the parasite population dynamics...
Elevated anti-malarial IgE in asymptomatic individuals is associated with reduced risk for subsequent clinical malariaSandor Bereczky
Infectious Diseases Unit, Karolinska University Hospital, Karolinska Institutet, S 171 76 Stockholm, Sweden
Int J Parasitol 34:935-42. 2004..Specific IgE antibodies may play role in maintaining anti-malarial immunity, or indicate other aspects of immune function relevant for protection against malaria...
