Ulrika Islander

Summary

Country: Sweden

Publications

  1. ncbi Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis
    Ulrika Islander
    Centre for Bone and Arthritis Research, The Sahlgrenska Academy, University of Gothenburg, Box 480, 405 30 Gothenburg, Sweden
    Arthritis Res Ther 13:R96. 2011
  2. ncbi Influence of oestrogen receptor alpha and beta on the immune system in aged female mice
    U Islander
    Department of Rheumatology, Goteborg University, Sweden
    Immunology 110:149-57. 2003
  3. ncbi Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen receptor-dependent
    U Islander
    Department of Rheumatology and Inflammation Research at the Sahlgrenska Academy, Goteborg, Sweden
    Clin Exp Immunol 139:210-5. 2005
  4. ncbi Estrogens in rheumatoid arthritis; the immune system and bone
    Ulrika Islander
    Center for Bone and Arthritis Research CBAR, Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy, University of Gothenburg, Sweden
    Mol Cell Endocrinol 335:14-29. 2011
  5. ncbi Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands
    Ulrika Islander
    Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, Goteborg University, Sweden
    BMC Immunol 6:16. 2005
  6. ncbi Superantigenic Staphylococcus aureus stimulates production of interleukin-17 from memory but not naive T cells
    Ulrika Islander
    Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Box 480, 405 30 Goteborg, Sweden
    Infect Immun 78:381-6. 2010
  7. ncbi Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and osteoporosis
    Caroline Jochems
    Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Arthritis Rheum 56:3261-70. 2007
  8. ncbi Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic arthritis
    Caroline Jochems
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    BMC Musculoskelet Disord 11:284. 2010
  9. ncbi Role of 2-methoxyestradiol as inhibitor of arthritis and osteoporosis in a model of postmenopausal rheumatoid arthritis
    Alexandra Stubelius
    Center for Bone and Arthritis Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Clin Immunol 140:37-46. 2011
  10. ncbi Ethanol prevents development of destructive arthritis
    Ing Marie Jonsson
    Department of Rheumatology and Inflammation Research and Center for Bone Research at the Sahlgrenska Academy, Goteborg University, SE 405 30 Goteborg, Sweden
    Proc Natl Acad Sci U S A 104:258-63. 2007

Detail Information

Publications17

  1. ncbi Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis
    Ulrika Islander
    Centre for Bone and Arthritis Research, The Sahlgrenska Academy, University of Gothenburg, Box 480, 405 30 Gothenburg, Sweden
    Arthritis Res Ther 13:R96. 2011
    ....
  2. ncbi Influence of oestrogen receptor alpha and beta on the immune system in aged female mice
    U Islander
    Department of Rheumatology, Goteborg University, Sweden
    Immunology 110:149-57. 2003
    ..Results from this study provide valuable information regarding the specific functions of ER-alpha and ER-beta in the aged immune system...
  3. ncbi Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen receptor-dependent
    U Islander
    Department of Rheumatology and Inflammation Research at the Sahlgrenska Academy, Goteborg, Sweden
    Clin Exp Immunol 139:210-5. 2005
    ..Thus, our study is the first to show that estren inhibits T lymphopoiesis via ER-independent pathways, whereas its suppressive effects on inflammation are ER-dependent...
  4. ncbi Estrogens in rheumatoid arthritis; the immune system and bone
    Ulrika Islander
    Center for Bone and Arthritis Research CBAR, Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy, University of Gothenburg, Sweden
    Mol Cell Endocrinol 335:14-29. 2011
    ..This review will focus on the influence of female sex hormones in the pathogenesis and progression of RA...
  5. ncbi Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands
    Ulrika Islander
    Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, Goteborg University, Sweden
    BMC Immunol 6:16. 2005
    ..Estrogen receptors (ERs) were blocked by treatment of mice with the ER-antagonist ICI 182,780; also, knock-out mice lacking one or both ERs were used...
  6. ncbi Superantigenic Staphylococcus aureus stimulates production of interleukin-17 from memory but not naive T cells
    Ulrika Islander
    Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Box 480, 405 30 Goteborg, Sweden
    Infect Immun 78:381-6. 2010
    ..These results suggest that superantigenic S. aureus are particularly efficient in stimulating IL-17 production and that the cytokine is produced from memory T cells...
  7. ncbi Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and osteoporosis
    Caroline Jochems
    Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Arthritis Rheum 56:3261-70. 2007
    ..We therefore used a mouse model of human RA to test the hypothesis that a selective estrogen receptor modulator (SERM), the raloxifene analog LY117018, could be beneficial in the treatment of both arthritis and osteoporosis...
  8. ncbi Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic arthritis
    Caroline Jochems
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    BMC Musculoskelet Disord 11:284. 2010
    ..We also examined whether treatment would prevent the development of inflammation-triggered generalized osteoporosis...
  9. ncbi Role of 2-methoxyestradiol as inhibitor of arthritis and osteoporosis in a model of postmenopausal rheumatoid arthritis
    Alexandra Stubelius
    Center for Bone and Arthritis Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Clin Immunol 140:37-46. 2011
    ..Joint destruction was reduced, neutrophils diminished and ROS production decreased. The uterine weight increased upon long-term 2me2 exposure, however short-term exposure did not activate ERE in vivo...
  10. ncbi Ethanol prevents development of destructive arthritis
    Ing Marie Jonsson
    Department of Rheumatology and Inflammation Research and Center for Bone Research at the Sahlgrenska Academy, Goteborg University, SE 405 30 Goteborg, Sweden
    Proc Natl Acad Sci U S A 104:258-63. 2007
    ..We conclude that low but persistent ethanol consumption delays the onset and halts the progression of collagen-induced arthritis by interaction with innate immune responsiveness...
  11. ncbi Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation
    Caroline Jochems
    Department of Rheumatology and Inflammation Research at the Sahlgrenska Academy, Goteborg, Sweden
    Arthritis Res Ther 7:R837-43. 2005
    ..Markers of bone remodeling and bone marrow lymphocyte phenotypes indicate different mechanisms for the development of osteoporosis caused by ovariectomy and arthritis in this model...
  12. ncbi Investigation of central versus peripheral effects of estradiol in ovariectomized mice
    Niklas Andersson
    Center for Bone Research at the Sahlgrenska Academy, Division of Endocrinology, Department of Internal Medicine, Goteborg University, Gröna stråket 8 SE 413 45 Göteborg, Sweden
    J Endocrinol 187:303-9. 2005
    ..05). These findings support the notion that the primary target tissue that mediates the effect of E2 on bone is peripheral and not central...
  13. ncbi Estrogenic agonism and antagonism of the soy isoflavone genistein in uterus, bone and lymphopoiesis in mice
    M C Erlandsson
    Department of Rheumatology and Inflammation Research, Goteborg University, Sweden
    APMIS 113:317-23. 2005
    ..The only agonistic effect of Gen was shown by increased BMD in OVX mice. Our results are discussed in the context of estrogen receptor biology...
  14. ncbi Oestrogen receptor specificity in oestradiol-mediated effects on B lymphopoiesis and immunoglobulin production in male mice
    M C Erlandsson
    Department of Rheumatology and Inflammation Research, Department of Internal Medicine, Goteborg University, Guldhedsgatan 10A, S 413 46 Goteborg, Sweden
    Immunology 108:346-51. 2003
    ..In conclusion our results clearly show that both ERalpha and ERbeta are required for complete down-regulation of B lymphopoiesis while only ERalpha is needed to up-regulate immunoglobulin production in both bone marrow and spleen...
  15. ncbi 17Beta-estradiol expands IgA-producing B cells in mice deficient for the mu chain
    M K Lagerquist
    Department of Rheumatology and Inflammation Research, Institution of Medicine, Goteborg University, Goteborg, Sweden
    Scand J Immunol 67:12-7. 2008
    ..In conclusion, we demonstrate that 17beta-estradiol benzoate increases the frequency of IgA-producing B cells in muMT-/- mice, suggesting that oestrogen can influence the alternative B-cell pathway found in muMT-/- mice...
  16. ncbi Galectin 3 aggravates joint inflammation and destruction in antigen-induced arthritis
    Huamei Forsman
    University of Gothenburg, Gothenburg, Sweden
    Arthritis Rheum 63:445-54. 2011
    ..We undertook this study to investigate the influence of galectin 3 deficiency in a murine model of arthritis...