Research Topics
Species | M HultcrantzSummaryCountry: Sweden Publications
| Collaborators
|
Detail Information
Publications
Pathology of the cochlea following a spontaneous mutation in DBA/2 miceM Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Acta Otolaryngol 117:689-95. 1997..Labelling of antibodies against fodrin increased in the supporting cells of the older animals, probably owing to the replacement of hair cells...
Turner's syndrome and hearing disorders in women aged 16-34M Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Hear Res 103:69-74. 1997..The data emphasize the importance of early audiological evaluation and information about predisposition to hearing impairment in Turner's syndrome...
Presence of glycosaminoglycans in the endolymphatic sacM Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Acta Otolaryngol 117:518-22. 1997..Keratan sulphate and chondroitin-4-sulphate+dermatan sulphate are present within the epithelial lining, in the subepithelial tissue, and to some minor extent in the lumen, while chondroitin-6-sulphate does not show any specific staining...
Characterization of hearing in an X,0 'Turner mouse'M Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, S 171 76, Stockholm, Sweden
Hear Res 143:182-8. 2000..This Turner mouse model appears to have ear and hearing problems quite similar to humans and can therefore be used as a model to determine the auditory pathology underlying this syndrome...
Estrogen receptors in the normal adult and developing human inner ear and in Turner's syndromeA E Stenberg
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Hear Res 157:87-92. 2001..No staining of estrogen receptor beta was seen in the fetal inner ear...
Effect of estrogen and antiestrogens on the estrogen receptor content in the cochlea of ovariectomized ratsA E Stenberg
Department of Otorhinolaryngology, Karolinska Hospital, 171 76, Stockholm, Sweden
Hear Res 182:19-23. 2003..When investigating the tissues with light microscopy no change in inner ear anatomy could be observed...
Estrogen and hearing: a summary of recent investigationsM Hultcrantz
Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden
Acta Otolaryngol 126:10-4. 2006..Knowing how sex steroids can alter hearing ability may give important clues as to how estrogen can preserve hearing in humans. In this review we present a summary of current knowledge about hearing and estrogen...
Estrogen receptors alpha and beta in the inner ear of the 'Turner mouse' and an estrogen receptor beta knockout mouseA E Stenberg
Department of Otorhinolaryngology, Karolinska Hospital, 171 76, Stockholm, Sweden
Hear Res 166:1-8. 2002..The betaERKO mice show close to normal inner ear morphology and positive estrogen receptor alpha immunostaining at the same locations as the CBA/Ca mouse...
Detection and localization of interleukin-6 in the rat middle ear during experimental acute otitis media, using mRNA in situ hybridization and immunohistochemistryM Forséni
Department of Otorhinolaryngology, Karolinska Hospital, Karolinska Institute, 171 76 Stockholm, Sweden
Int J Pediatr Otorhinolaryngol 57:115-21. 2001..This study aimed to describe the localization of interleukin (IL)-6 mRNA and its gene product in the rat middle ear during pneumococcal otitis media. IL-6 is known to be involved in inflammatory and bone remodeling processes...
The menopause triggers hearing decline in healthy womenC Hederstierna
Division of Otorhinolaryngology and Hearing, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
Hear Res 259:31-5. 2010....
Ear and hearing problems in Turner's syndromeM Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Acta Otolaryngol 123:253-7. 2003..To report hearing results in Swedish women with Turner's syndrome (TS), describe the recommendations of the Otologic Section of the Swedish Turner Academy for handling these patients and discuss the effect of estrogen on hearing in animals...
Alloreactivity but failure to reject human islet transplants by humanized Balb/c/Rag2gc miceS Jacobson
Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
Scand J Immunol 71:83-90. 2010..These observations question the usefulness of the HIS mouse model for studies on human islet allograft rejection mechanisms and highlight the need for further improvements...
Turnover of sulphated macromolecules in the murine endolymphatic sac after long-term kanamycin treatmentM Hultcrantz
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Am J Otolaryngol 10:386-92. 1989..In 12 control animals, no difference in the distribution of labeling was observed, but there was an additional uptake in the free intraluminal cells which was not seen in the kanamycin group...
A study of inflammatory mediators in the human tympanosclerotic middle earM Forséni
Department of Plastic and Reconstructive Surgery, Karolinska Hospital, 171 76 Stockholm, Sweden
Arch Otolaryngol Head Neck Surg 127:559-64. 2001....
Aspects of diagnosis of acute otitis mediaC Hemlin
Department of Oto Rhino Laryngology and Head and Neck Surgery, Karolinska Hospital, Stockholm, Sweden
Fam Pract 15:133-7. 1998..Acute otitis media is a common disease, particularly among children. The importance of a correct diagnosis is crucial, especially as unjustified prescription of antibiotics has become a major problem in clinical praxis...
Cochlear distribution of Na,K-ATPase and corticosteroid receptors in two mouse strains with congenital hearing disordersS Erichsen
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Acta Otolaryngol 121:794-802. 2001..The conclusion that reduced Na,K-ATPase levels in both mouse strains may be an important mechanism of the disturbed endolymph production is less controversial...
Psychosocial work environment and lifestyle as related to lipid profiles in perimenopausal womenA Evolahti
Karolinska Institute, Department of Clinical Neuroscience, Stockholm, Sweden
Climacteric 12:131-45. 2009..The aim of the study was to characterize lipid profiles of perimenopausal women and to relate these to the psychosocial work environment and lifestyle using a longitudinal design...
Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptorS Erichsen
Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden
Hear Res 160:37-46. 2001..The hypothesis that mineralocorticoid hormone alone via MR stimulates the formation of Na,K-ATPase in the inner ear could not be confirmed by this study, and other regulating mechanisms must be considered...
