Research Topics
Species | Einar BjornssonSummaryCountry: Sweden Publications
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Publications
Outcome and prognostic markers in severe drug-induced liver diseaseEinar Bjornsson
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, SE 413 45 Gothenburg, Sweden
Hepatology 42:481-9. 2005..In conclusion, hepatocellular jaundice has a high but variable mortality rate, depending on the drug involved. The AST and bilirubin levels are the most important predictors of death or liver transplantation...
Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-upEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Liver Int 30:251-8. 2010..Fatigue was recently suggested to predict an increased risk of mortality in a primary biliary cirrhosis (PBC) cohort during follow-up...
Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional studyEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
BMC Gastroenterol 8:46. 2008..We aimed to determine the impact of cirrhosis etiology on hepatic encephalopathy and whether hepatic encephalopathy affects health-related QoL among patients with cirrhosis of different etiologies...
Clinical characteristics and prognostic markers in disulfiram-induced liver injuryEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, SE 413 45 Gothenburg, Sweden
J Hepatol 44:791-7. 2006..Limited systematic data exists on the incidence of drug-induced hepatotoxicity due to disulfiram and the most important prognostic markers. We aimed to determine the nature and frequency of suspected disulfiram hepatotoxicity in Sweden...
Long-term follow-up of patients with acute liver failure of indeterminate aetiologyGu Wei
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 43:984-91. 2008....
Malnutrition and diabetes mellitus are related to hepatic encephalopathy in patients with liver cirrhosisEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Liver Int 27:1194-201. 2007..Our aim was to investigate the effects of malnutrition and diabetes mellitus on HE in unselected patients with liver cirrhosis...
Health-related quality of life in patients with different stages of liver disease induced by hepatitis CEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 44:878-87. 2009..The aim of this study was to determine HRQoL in patients in different stages of hepatitis C virus (HCV) and to compare HRQoL in HCV cirrhosis with non-HCV-induced cirrhosis...
The relationship between symptoms, body mass index, gastrointestinal transit and stool frequency in patients with irritable bowel syndromeRiadh Sadik
Department of Internal Medicine, Sahlgrenska University Hospital, Göteborg 41345, Sweden
Eur J Gastroenterol Hepatol 22:102-8. 2010..The aim of this prospective study was to characterize the relationships between symptoms in IBS, GI transit, as a measure of GI motility, and BMI...
Drug-induced autoimmune hepatitis: clinical characteristics and prognosisEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Landspitali University Hospital, Reykjavik, Iceland
Hepatology 51:2040-8. 2010..These two groups have similar clinical and histological patterns. However, DIAIH patients do not seem to require long-term immunosuppressive therapy...
Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosisEvangelos Kalaitzakis
Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Clin Gastroenterol Hepatol 7:346-52. 2009....
The natural history of drug-induced liver injuryEinar Bjornsson
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Semin Liver Dis 29:357-63. 2009..Recent studies have shown that DILI can infrequently evolve into chronic liver injury including cirrhosis and even liver-related morbidity and mortality in a minority of patients...
Inadequate use of proton-pump inhibitors in patients with liver cirrhosisEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Eur J Gastroenterol Hepatol 20:512-8. 2008..Patients with liver cirrhosis have a high prevalence of gastrointestinal symptoms. The use of antiacid therapy (AAT) in these patients is unexplored. We aimed to assess the use of AAT in cirrhotic patients...
Coronary artery disease in patients with liver cirrhosisEvangelos Kalaitzakis
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden
Dig Dis Sci 55:467-75. 2010..We aimed to determine the prevalence and predictive factors of CAD in a cohort of consecutive patients with cirrhosis of various etiologies compared to the general population...
Small-duct primary sclerosing cholangitisEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Med Pol II, SE 413 45 Gothenburg, Sweden
Curr Gastroenterol Rep 11:37-41. 2009..Recurrence of small-duct PSC after liver transplantation has been reported. Cholangiocarcinoma, the most feared complication of PSC, has not been described in a patient with small-duct PSC without progression first to large-duct PSC...
The long-term follow-up after idiosyncratic drug-induced liver injury with jaundiceEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
J Hepatol 50:511-7. 2009..Chronic evolution after drug-induced liver injury (DILI) has been reported. How often this leads to liver-related morbidity and mortality is unexplored...
Dyspeptic symptom development after discontinuation of a proton pump inhibitor: a double-blind placebo-controlled trialAnna Niklasson
Department of Internal Medicine, Section of Gastroenterology, Sahlgrenska University Hospital, Richertsgatan 18, Göteborg 412 60, Sweden
Am J Gastroenterol 105:1531-7. 2010..Conflicting data exist on whether discontinuation of proton pump inhibitors (PPIs) is associated with rebound secretion of gastric acid...
Autoimmune hepatitis-PBC overlap syndrome: a simplified scoring system may assist in the diagnosisMatthias Neuhauser
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
Am J Gastroenterol 105:345-53. 2010..Furthermore, we sought to compare the outcome in PBC patients with and without the features of AIH overlap...
Altered postprandial glucose, insulin, leptin, and ghrelin in liver cirrhosis: correlations with energy intake and resting energy expenditureEvangelos Kalaitzakis
Department of Internal Medicine, Faculty of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Am J Clin Nutr 85:808-15. 2007..Liver cirrhosis is associated with reduced energy intake and increased resting energy expenditure...
The natural history of small-duct primary sclerosing cholangitisEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Gastroenterology 134:975-80. 2008..We aimed at determining the natural history and long-term outcomes of a large number of patients with small-duct PSC...
Role of gastric sensorimotor dysfunction in gastrointestinal symptoms and energy intake in liver cirrhosisEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 42:237-46. 2007..The aim of this study was to investigate gastric accommodation to a meal and sensitivity to gastric distension with reference to energy intake, nutritional status and gastrointestinal symptoms in liver cirrhosis...
Primary sclerosing cholangitis associated with elevated immunoglobulin G4: clinical characteristics and response to therapyEinar Bjornsson
Division of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Am J Ther 18:198-205. 2011..Most patients had a good biochemical response to steroids, but adverse effects were common. Future work should be directed at finding therapy that is more effective, better tolerated, and of more lasting benefit...
Prevalence of gastrointestinal symptoms in patients with chronic obstructive pulmonary diseaseAnna Niklasson
Department of Internal Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
Eur J Gastroenterol Hepatol 20:335-41. 2008....
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomesSteingerdur Anna Gunnarsdottir
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 44:984-93. 2009..The incidence and mortality of liver cirrhosis in Iceland has been reported to be the lowest in the Western world. There are very few data on aetiology, incidence and prognosis among cirrhotics in Sweden...
Renal function and cognitive impairment in patients with liver cirrhosisEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 42:1238-44. 2007..Renal function has been shown to be important for ammonia metabolism in cirrhosis. Although renal dysfunction is common in cirrhotic patients, its effect on cognitive function is largely unexplored...
Hepatotoxicity associated with statins: reports of idiosyncratic liver injury post-marketingEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland
J Hepatol 56:374-80. 2012..Limited data exist on drug-induced liver injury (DILI) associated with statins...
Abstinence in patients with alcoholic liver cirrhosis: A follow-up studyEvangelos Kalaitzakis
Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Hepatol Res 38:869-76. 2008..Cirrhosis severity (expressed as the MELD) and alcohol abuse treatment during follow up were related to short-term mortality...
A review of esomeprazole in the treatment of gastroesophageal reflux disease (GERD)Evangelos Kalaitzakis
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital Gothenburg, Sweden
Ther Clin Risk Manag 3:653-63. 2007....
Fate of patients with obstructive jaundiceEinar Bjornsson
Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
J Hosp Med 3:117-23. 2008..Systematic data are limited on the etiology and prognosis of unselected patients with obstructive jaundice (OJ). We aimed to review the clinical features, etiology, and prognosis of patients with OJ...
Gastrointestinal symptoms in patients with liver cirrhosis: associations with nutritional status and health-related quality of lifeEvangelos Kalaitzakis
Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 41:1464-72. 2006..Our aim was to prospectively evaluate gastrointestinal symptoms, malnutrition, and QoL in patients with cirrhosis...
Fulminant drug-induced hepatic failure leading to death or liver transplantation in SwedenEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Gastroenterol 40:1095-101. 2005..The aim of this study was to determine the nature and number of suspected adverse drug-induced liver disease associated with fatalities and/or liver transplantation since reporting of adverse drug reactions (ADRs) started in Sweden...
Long-term follow-up of patients with alcoholic liver disease after liver transplantation in Sweden: impact of structured management on recidivismEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, SE 413 45 Gothenburg, Sweden
Scand J Gastroenterol 40:206-16. 2005..Data are limited on the impact of structured management of the alcohol problem on the risk of recidivism following transplantation in ALD...
