A review of the efficacy and safety of banaba (Lagerstroemia speciosa L.) and corosolic acidSidney J Stohs
Creighton University, Medical Center, Omaha, NE 68178, USA
Phytother Res 26:317-24. 2012
..Banaba extract, corosolic acid and other constituents may be beneficial in addressing the symptoms associated with metabolic syndrome, as well as offering other health benefits...
A review of the receptor-binding properties of p-synephrine as related to its pharmacological effectsSidney J Stohs
School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA
Oxid Med Cell Longev 2011:482973. 2011
..This paper summarizes the adrenoreceptor binding characteristics of p-synephrine relative to m-synephrine, norepinephrine, and other amines as related to the observed pharmacological effects...
Nutritional supplements in the surgical patientSidney J Stohs
Creighton University Medical Center, Omaha, NE, USA
Surg Clin North Am 91:933-44, x. 2011
..Recent revisions and recommendations for some of the macronutrients are presented, together with a summary of federal regulations and an oversight of supplements...
The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrineSidney J Stohs
School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA
Phytother Res 25:1421-8. 2011
..The data indicate that based on current knowledge, the use of bitter orange extract and p-synephrine appears to be exceedingly safe with no serious adverse effects being directly attributable to these ingredients...
Comparative effects of selected non-caffeinated rehydration sports drinks on short-term performance following moderate dehydrationPeter G Snell
Creighton University Health Sciences Center, Omaha, NE, USA
J Int Soc Sports Nutr 7:28. 2010
..The effect of moderate dehydration and consequent fluid replenishment on short-duration maximal treadmill performance was studied in eight healthy, fit (VO2max = 49.7 +/- 8.7 mL kg-1 min-1) males aged 28 +/- 7.5 yrs...
No evidence demonstrating hepatotoxicity associated with hydroxycitric acidSidney J Stohs
School of Pharmacy and Health Professions, Creighton University Medical Center, 4967 Stillwater Trail, Frisco, TX 75034, United States
World J Gastroenterol 15:4087-9. 2009
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Physico-chemical properties of a novel (-)-hydroxycitric acid extract and its effect on body weight, selected organ weights, hepatic lipid peroxidation and DNA fragmentation, hematology and clinical chemistry, and histopathological changes over a period oMichael Shara
Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA
Mol Cell Biochem 260:171-86. 2004
..Taken together, these results show that 90 day treatment of HCA-SX results in a reduction in body weight, and does not cause any changes in major organs or in hematology, clinical chemistry, and histopathology...
Antimicrobial effects of antioxidants with and without clarithromycin on Helicobacter pyloriArchana Chatterjee
Department of Pediatrics, Division of Pediatric Infectious Diseases, Creighton University Medical Center, Omaha, NE 68131, USA
Mol Cell Biochem 270:125-30. 2005
..pylori growth compared to controls. We conclude from this study that some antioxidants such as vitamin C, garcinol and Protykin, but not vitamin E, may have potential as antimicrobial agents against H. pylori...
Safety and toxicological evaluation of a novel niacin-bound chromium (III) complexMichael Shara
Creighton University Medical Center, Omaha, NE, USA
J Inorg Biochem 99:2161-83. 2005
..Hematology, clinical chemistry and histopathological evaluations did not show any adverse effects in all organs tested. Taken together, the above results indicate a broad spectrum of safety for NBC...
Dose- and time-dependent effects of a novel (-)-hydroxycitric acid extract on body weight, hepatic and testicular lipid peroxidation, DNA fragmentation and histopathological data over a period of 90 daysMichael Shara
Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA
Mol Cell Biochem 254:339-46. 2003
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Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycinArchana Chatterjee
Department of Pediatrics, Creighton University Health Sciences Center, Omaha, NE 68131, USA
Mol Cell Biochem 265:19-26. 2004
..All berry extracts significantly (p < 0.05) inhibited H. pylori, compared with controls, and also increased susceptibility of H. pylori to clarithromycin, with OptiBerry demonstrating maximal effects...
Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changesSidney J Stohs
Dean Emeritus, Creighton University Health Sciences Center, Omaha, NE 68178, USA
Int J Med Sci 8:295-301. 2011
..This unusual finding of a thermogenic combination of ingredients that elevated metabolic rates without corresponding elevations in blood pressure and heart-rates warrants longer term studies to assess its value as a weight control agent...
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extractDebasis Bagchi
Creighton University School of Pharmacy and Allied Health Professions, Omaha, NE 68178, USA
Indian J Exp Biol 40:717-26. 2002
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Safety assessment of a calcium-potassium salt of (-)-hydroxycitric acidSidney J Stohs
School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA
Toxicol Mech Methods 20:515-25. 2010
..There were no macroscopic abnormalities for any examined tissues at scheduled necropsies. On the basis of these findings, the consumption of HCA-SX at dose level of up to 4667?mg/day is considered safe...
The bactericidal effects of Lactobacillus acidophilus, garcinol and Protykin compared to clarithromycin, on Helicobacter pyloriArchana Chatterjee
Department of Pediatrics, Creighton University Health Sciences Center, Omaha, NE 68178, USA
Mol Cell Biochem 243:29-35. 2003
..pylori at 6 and 12 h incubation, indicating a potential role for this antioxidant in treatment for H. pylori infection...
Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX)Sunny E Ohia
Department of Pharmacy Sciences, Creighton University School of Pharmacy and Allied Health Professions, Omaha, NE 68178, USA
Mol Cell Biochem 238:89-103. 2002
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