Research Topics
| Wanigasekera D RatnasooriyaSummaryAffiliation: University of Colombo Country: Sri Lanka Publications
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Detail Information
Publications
Effects of Sri Lankan black tea (Camellia sinensis L.) on pregnancy of ratsWanigasekera D Ratnasooriya
Department of Zoology, University of Colombo, Colombo, Sri Lanka
Basic Clin Pharmacol Toxicol 105:361-5. 2009..If the results are applicable to women, it is concluded that even heavy consumption of black tea brew during pregnancy may not be harmful for pregnancy outcome...- Antioxidant activity of water extract of Scoparia dulcisW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
Fitoterapia 76:220-2. 2005..An aqueous extract of Scoparia dulcis showed marked antioxidative activity in vitro, which supports the therapeutic effects claimed by traditional practitioners... - Effects of aqueous extract of Alpinia calcarata rhizomes on reproductive competence of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
Acta Biol Hung 57:23-35. 2006..Further, the HWE was nontoxic. It is concluded that A. calcarata rhizomes possess a strong and safe oral aphrodisiac activity... - Sedative activity of stem bark of the Sri Lankan endemic plant, Vateria copalliferaW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 3, Sri Lanka
Fitoterapia 77:331-2. 2006..An aqueous bark extract of Vateria copallifera showed marked sedative activity, which supports the therapeutic effects claimed by Sri Lankan traditional physicians... - Effect of black tea brew of Camellia sinensis on sexual competence of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
J Ethnopharmacol 118:373-7. 2008..O. Kuntze (Theaceae) is claimed to have male sexual stimulant activity. As this claim is not scientifically tested and proven, this study was undertaken to evaluate the effects of BTB on male sexual competence... - Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundoM G Dharmasiri
Department of Zoology, University of Colombo, 3, Colombo, Sri Lanka
J Ethnopharmacol 87:199-206. 2003..The antihistamine activity can produce the anti-itching effect claimed in Ayurveda medicine... - Antinociceptive action of aqueous extract of the leaves of Ixora coccineaW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
Acta Biol Hung 56:21-34. 2005..Dopaminergic and antioxidative activities of ALE could arise, respectively, from its quaternary base alkaloid and flavonoid constituents... - Leaf extract of Crinum bulbispermum has antinociceptive activity in ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
J Ethnopharmacol 97:123-8. 2005..Additionally, the ALE had antihyperalgesic activity. The antinociception of the ALE appear to results from opioid mechanisms, sedation and antioxidant activities. Unfortunately, ALE is mild to moderately toxic... - Sodium nitroprusside impairs sexual competence of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 3, Sri Lanka
Hum Exp Toxicol 23:187-92. 2004..It is concluded that SNP impairs male sexual competence, at least, in rats although it promotes penile erection... - Diuretic activity of Spilanthes acmella flowers in ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
J Ethnopharmacol 91:317-20. 2004..It may also inhibit ADH release and/or action. It is concluded that the Spilanthes acmella CWE has strong diuretic action as is claimed... - Antidiuretic activity of aqueous bark extract of Sri Lankan Ficus racemosa in ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
Acta Biol Hung 54:357-63. 2003..The results provide scientific support for its claimed antidiuretic action and deserve intensive scrutiny... - Adverse pregnancy outcome in rats following exposure to a Salacia reticulata (Celastraceae) root extractW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo, Sri Lanka
Braz J Med Biol Res 36:931-5. 2003..9 2.6 vs 57.1 16.1%). However, the root extract was non-teratogenic. We conclude that the S. reticulata root extract can be hazardous to successful pregnancy in women and should not be used in pregnancy complicated by diabetes... - Antinociceptive effect and toxicological study of the aqueous bark extract of Barringtonia racemosa on ratsS A Deraniyagala
Department of Chemistry, University of Colombo, P O Box 1490, Colombo, Sri Lanka
J Ethnopharmacol 86:21-6. 2003..The antinociceptive effect was mediated mainly via opioid mechanisms. Such inhibition of pain could arise from phenolic and steroidal constituents as was shown to be present in the extract... - Effects of Icon, a pyrethroid insecticide on early pregnancy of ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 3, Sri Lanka
Hum Exp Toxicol 22:523-33. 2003..Further progesterone had a protective effect against Icon induced anti-reproductive actions. Overall, the results suggest that exposure to Icon during early gestation may result in a threat to pregnancy... - Long-term administration of large doses of paracetamol impairs the reproductive competence of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 3, Sri Lanka
Asian J Androl 2:247-55. 2000..To evaluate the antireproductive effect of paracetamol in male rats... - Effects of Terminalia catappa seeds on sexual behaviour and fertility of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Sri Lanka
Asian J Androl 2:213-9. 2000..To evaluate the aphrodisiac potential of Tenminalia catappa Linn. seeds using a suspension of its kernel (SS) in 1% methyl cellulose in rats... - Human sperm motility stimulating activity of a sulfono glycolipid isolated from Sri Lankan marine red alga Gelidiella acerosaG A Premakumara
Natural Products Development Group, Industrial Technology Institute (CISIR, Colombo, Sri Lanka
Asian J Androl 3:27-31. 2001..CONCLUSION: S-ACT-1 of Gelidiella acerosa is a Sulfono glycolipid. S-ACT-1 has a potent sperm motility stimulating activity in vitro and has the potential to be developed into a sperm stimulant... - L-arginine, the substrate of nitric oxide synthase, inhibits fertility of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Sri Lanka
Asian J Androl 3:97-103. 2001..To examine the effect of L-arginine, the substrate of nitric oxide (NO) synthase, on reproductive function of male rats... - Effects of pyrethroid insecticide ICON (lambda cyhalothrin) on reproductive competence of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Sri Lanka
Asian J Androl 4:35-41. 2002..To assess the effect of ICON (trade name of lambda-cyhalothrin) on sexual competence and fertility of male rats... - Artocarpus heterophyllus seeds inhibits sexual competence but not fertility of male ratsW D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 03, Sri Lanka
Indian J Exp Biol 40:304-8. 2002..In a mating study, SS failed to alter ejaculating competence and fertility. These results suggest that A. heterophyllous seeds do not have aphrodisiac action, at least, in rats... - Effects of the prostanoid receptor antagonist, di-4-phloretin phosphate, upon human sperm motilityW D Ratnasooriya
Department of Zoology, University of Colombo, Sri Lanka
Contraception 45:239-48. 1992..25 mM) of DPP, and the mechanism precipitating the antimotility effect may involve mobilization of stored calcium ions and modulation of cyclic AMP levels... - Antidiabetic activities of aqueous and ethanolic extracts of Piper betle leaves in ratsL S R Arambewela
Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7, Sri Lanka
J Ethnopharmacol 102:239-45. 2005..However, the weight of the spleen had increased in treated groups possibly indicating lymphoproliferative activity. It is concluded that HWE and CEE of Piper betle leaves possess safe and strong antidiabetic activity... - Effect of Withania somnifera root extract on the sexual behaviour of male ratsI Ilayperuma
Department of Anatomy, Faculty of Medicine, University of Ruhuna, Sri Lanka
Asian J Androl 4:295-8. 2002..CONCLUSION: Use of W. somnifera roots may be detrimental to male sexual competence... - Antinociceptive activities of aqueous and ethanolic extracts of Alpinia calcarata rhizomes in ratsL S R Arambewela
Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7, Sri Lanka
J Ethnopharmacol 95:311-6. 2004..The antinociceptive effect was slightly higher in HEE than that of HWE. The antinociceptive effect was mediated via opioid mechanisms... - Rediscovering Boveri's centrosome in Ascaris (1888): its impact on human fertility and developmentA H Sathananthan
Centre for Early Human Development and Monash Immunology and Stem Cell Laboratories, Monash University, Melbourne, Australia
Reprod Biomed Online 12:254-70. 2006..We now know the origins of the centrosome in human somatic cells--predominantly from the sperm cell. The impact of Boveri's work on human development is highlighted in this age of assisted reproductive technology...