P Villoslada

Summary

Country: Spain

Publications

  1. ncbi Cognitive impairment in patients with multiple sclerosis using the Brief Repeatable Battery-Neuropsychology test
    J Sepulcre
    Department of Neurology, Multiple Sclerosis Centre, Clinica Universitaria, University of Navarra, Spain
    Mult Scler 12:187-95. 2006
  2. ncbi Increased expression of cystine/glutamate antiporter in multiple sclerosis
    Olatz Pampliega
    Neurotek UPV EHU, Parque Tecnologico de Bizkaia, Zamudio, Bizkaia, Spain
    J Neuroinflammation 8:63. 2011
  3. ncbi Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
  4. ncbi Computational disease modeling - fact or fiction?
    Jesper N Tegnér
    Computational Medicine group, Department of Medicine, Center for Molecular Medicine, Karolinska University Hospital, Solna, Stockholm, Sweden
    BMC Syst Biol 3:56. 2009
  5. ncbi Computational classifiers for predicting the short-term course of Multiple sclerosis
    Bartolome Bejarano
    Department of Neuroscience, CIMA University of Navarra, Pamplona, Spain
    BMC Neurol 11:67. 2011
  6. ncbi Targeting NGF pathway for developing neuroprotective therapies for multiple sclerosis and other neurological diseases
    Valeria Colafrancesco
    Center for Neuroimmunology, IDIBAPS, Hospital Clinic of Barcelona, Spain
    Arch Ital Biol 149:183-92. 2011
  7. ncbi Biomarkers for multiple sclerosis
    Pablo Villoslada
    Department of Neurosciences, Institute of Biomedical Research August Pi Sunyer, Hospital Clinic of Barcelona, Barcelona, Spain
    Drug News Perspect 23:585-95. 2010
  8. ncbi Systems biology and its application to the understanding of neurological diseases
    Pablo Villoslada
    Department of Neuroscience, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Ann Neurol 65:124-39. 2009
  9. ncbi Memantine induces reversible neurologic impairment in patients with MS
    P Villoslada
    Department of Neurology, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Neurology 72:1630-3. 2009
  10. ncbi Abnormalities in brain synchronization are correlated with cognitive impairment in multiple sclerosis
    G Arrondo
    Department of Neurosciences, CIMA University of Navarra, Pamplona, Spain
    Mult Scler 15:509-16. 2009

Collaborators

Detail Information

Publications15

  1. ncbi Cognitive impairment in patients with multiple sclerosis using the Brief Repeatable Battery-Neuropsychology test
    J Sepulcre
    Department of Neurology, Multiple Sclerosis Centre, Clinica Universitaria, University of Navarra, Spain
    Mult Scler 12:187-95. 2006
    ..CONCLUSIONS: Our data show that cognitive impairment is prevalent amongst MS patients, and that a single cognitive measurement might be useful for monitoring patients during the progression of this illness...
  2. ncbi Increased expression of cystine/glutamate antiporter in multiple sclerosis
    Olatz Pampliega
    Neurotek UPV EHU, Parque Tecnologico de Bizkaia, Zamudio, Bizkaia, Spain
    J Neuroinflammation 8:63. 2011
    ..The objective of this study was to analyze the role of the system x(c)? in glutamate homeostasis alterations in MS pathology...
  3. ncbi Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
    ..g. failure in central tolerance, activation by pathogens) that are able to trigger the immune system...
  4. ncbi Computational disease modeling - fact or fiction?
    Jesper N Tegnér
    Computational Medicine group, Department of Medicine, Center for Molecular Medicine, Karolinska University Hospital, Solna, Stockholm, Sweden
    BMC Syst Biol 3:56. 2009
    ..On the other hand, the physics-inspired top-down modeling strategy identifies and selects features of (presumably) essential relevance to the phenomena of interest and combines available data in models of modest complexity...
  5. ncbi Computational classifiers for predicting the short-term course of Multiple sclerosis
    Bartolome Bejarano
    Department of Neuroscience, CIMA University of Navarra, Pamplona, Spain
    BMC Neurol 11:67. 2011
    ..The aim of this study was to assess the diagnostic accuracy (sensitivity and specificity) of clinical, imaging and motor evoked potentials (MEP) for predicting the short-term prognosis of multiple sclerosis (MS)...
  6. ncbi Targeting NGF pathway for developing neuroprotective therapies for multiple sclerosis and other neurological diseases
    Valeria Colafrancesco
    Center for Neuroimmunology, IDIBAPS, Hospital Clinic of Barcelona, Spain
    Arch Ital Biol 149:183-92. 2011
    ..Therefore, because its neuroprotective activity and immunomodulatory effects, NGF may represent a new therapeutic approach for the treatment of numerous brain disorders...
  7. ncbi Biomarkers for multiple sclerosis
    Pablo Villoslada
    Department of Neurosciences, Institute of Biomedical Research August Pi Sunyer, Hospital Clinic of Barcelona, Barcelona, Spain
    Drug News Perspect 23:585-95. 2010
    ..Indeed, it may currently be necessary to redress the bias in research towards clinical validation rather than discovery in order to promote translational research and improve patient's quality of life...
  8. ncbi Systems biology and its application to the understanding of neurological diseases
    Pablo Villoslada
    Department of Neuroscience, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Ann Neurol 65:124-39. 2009
    ..This new knowledge will contribute to the development of patient-specific therapeutic approaches, bringing the paradigm of personalized medicine one step closer to reality...
  9. ncbi Memantine induces reversible neurologic impairment in patients with MS
    P Villoslada
    Department of Neurology, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Neurology 72:1630-3. 2009
    ..Cognitive dysfunction is very common in multiple sclerosis (MS) and it severely impairs patients' quality of life. Thus, we explored whether memantine might improve cognitive performance in patients with MS...
  10. ncbi Abnormalities in brain synchronization are correlated with cognitive impairment in multiple sclerosis
    G Arrondo
    Department of Neurosciences, CIMA University of Navarra, Pamplona, Spain
    Mult Scler 15:509-16. 2009
    ..Auditory amplitude modulation following responses (AMFR), are oscillatory steady-state responses to rhythmic auditory stimuli that indirectly measure brain synchrony...
  11. ncbi Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways
    J Sepulcre
    Department of Neurology and Neurosurgery, University of Navarra, Pamplona, Spain
    Mult Scler 15:337-44. 2009
    ..Fatigue is one of the most frequent and disturbing symptoms in multiple sclerosis (MS), directly affecting the patient's quality of life. However, many questions remain unclear regarding the anatomic brain correlate of MS-related fatigue...
  12. ncbi Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis
    J Toledo
    Department of Neurology and Neurosurgery, Clinica Universitaria de Navarra and Center for Applied Medical Research, University of Navarra, Pamplona, Spain
    Mult Scler 14:906-12. 2008
    ....
  13. ncbi Memory decline evolves independently of disease activity in MS
    B Duque
    Department of Neurology, Clinica Universitaria de Navarra and Center for Applied Medical Research, University of Navarra, Spain
    Mult Scler 14:947-53. 2008
    ..Clinical evaluation included assessment of new relapses and changes in disability (Extended Disability Status Scale (EDSS)) confirmed at 6 months...
  14. ncbi Analysis of relapses in anti-NMDAR encephalitis
    I Gabilondo
    Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
    Neurology 77:996-9. 2011
    ..The clinical characteristics of patients with relapsing anti-NMDA receptor (NMDAR) encephalitis are not well-defined. In this study, we report the clinical profile and outcome of relapses in a series of anti-NMDAR encephalitis...
  15. ncbi The immune response against herpesvirus is more prominent in the early stages of MS
    P Villoslada
    Neuroimmunology Unit, Hospital Vall d Hebron, Barcelona, Spain
    Neurology 60:1944-8. 2003
    ..To assess antibody levels against human herpesvirus type 6 (HHV-6), Epstein-Barr virus (EBV), and Chlamydia pneumoniae (CP) in serum from individuals in the early and late phase of MS...