Research Topics
| Josep RedonSummaryAffiliation: University of Valencia Country: Spain Publications
| Collaborators
|
Detail Information
Publications
Practical solutions to the challenges of uncontrolled hypertension: a white paperJosep Redon
Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, Valencia, Spain
J Hypertens Suppl 26:S1-14. 2008....- The metabolic syndrome in hypertension: European society of hypertension position statementJosep Redon
University of Valencia and CIBER 06 03 Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
J Hypertens 26:1891-900. 2008..If a combination of drugs is required, low-dose diuretics can be used. A combination of thiazide diuretics and beta-blockers should be avoided... - Kidney function and cardiovascular disease in the hypertensive population: the ERIC-HTA studyJosep Redon
Hypertension Unit, Clinic Hospital of Valencia, Valencia University, Valencia, Spain
J Hypertens 24:663-9. 2006.... - [Prevalence of low glomerular filtration rate in the elderly population of Spain. The PREV-ICTUS study]Luis Cea Calvo
Departamento de Investigación Clínica, Merck Sharp and Dohme de Espana, Madrid, Spain
Med Clin (Barc) 129:681-7. 2007..To assess the prevalence of low glomerular filtration rate (GFR < 60 ml/min/1.73 m2) in general population of subjects aged 60 years or older of Spain, and the related factors... - Independent impact of obesity and fat distribution in hypertension prevalence and control in the elderlyJosep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia, and CIBER of Obesity and Nutrition CB 03 06, Carlos III Institute of Health, Madrid, Spain
J Hypertens 26:1757-64. 2008..Studies on the impact of weight excess and fat distribution on blood pressure are usually limited to young and middle-aged population, and data on the elderly are scarce... - Added impact of obesity and insulin resistance in nocturnal blood pressure elevation in children and adolescentsEmpar Lurbe
Pediatric Department, Consorcio Hospital General, University of Valencia, Valencia, Spain
Hypertension 51:635-41. 2008.... - Differences in blood pressure control and stroke mortality across Spain: the Prevención de Riesgo de Ictus (PREV-ICTUS) studyJosep Redon
Hypertension Clinic, Hospital Clinico Universitario, Universidad de Valencia, Spain
Hypertension 49:799-805. 2007..Differences in stroke mortality throughout the autonomic communities of Spain were associated with indexes of worse blood pressure handling, low control rates, and high left-ventricular hypertrophy... - Influence of concurrent obesity and low birth weight on blood pressure phenotype in youthEmpar Lurbe
Department of Pediatrics, Consorcio Hospital General, University of Valencia, Valencia, Spain
Hypertension 53:912-7. 2009..005) existed. In conclusion, although the low birth weight children who become obese have the highest systolic BP values, the presence of obesity blunts the increment of the reflecting wave observed in low birth weight subjects... - Metabolic syndrome, organ damage and cardiovascular disease in treated hypertensive patients. The ERIC-HTA studyJorge Navarro
Salvador Pau Heath Care Center, Valencia, Spain
Blood Press 16:20-7. 2007.... - The impact of occult renal failure on the cardiovascular risk stratification in an elderly population: the PREV-ICTUS studyJosep Redon
Hypertension Clinic, Hospital Clinico Universitario, Universidad de Valencia, Spain
Blood Press 17:212-9. 2008..To analyze the impact of occult renal failure (ORF) in the individual risk stratification and on the blood pressures (BP) and low-density lipoprotein (LDL) goals in an aged population, according to the ESH/ESC Hypertension Guidelines... - Serum lipid profiles and their relationship to cardiovascular disease in the elderly: the PREV-ICTUS studyJose V Lozano
Serrería 2 Health Center, Valencia, Spain
Curr Med Res Opin 24:659-70. 2008..To assess the relationship between different serum lipid profiles and the prevalence of established cardiovascular disease (CVD) in an elderly population... - Mechanisms of hypertension in the cardiometabolic syndromeJosep Redon
University of Valencia, CIBER 06 03 Fisiopatología de la Obesidad y Nutrición, Institute of Health Carlos III, Madrid, Spain
J Hypertens 27:441-51. 2009.... - Polymorphisms of antioxidant enzymes, blood pressure and risk of hypertensionMaria L Mansego
Genotyping and Genetic Diagnosis Unit, Hospital Clínico Research Foundation and INCLIVA, Valencia, Spain
J Hypertens 29:492-500. 2011..To assess the association of single-nucleotide polymorphisms (SNPs) in genes codifying for antioxidant enzymes to blood pressure (BP) values and risk of hypertension... - Determinants of urinary albumin excretion reduction in essential hypertension: A long-term follow-up studyJose Maria Pascual
Hypertension Clinics of Sagunto Hospital, University of Valencia, Spain
J Hypertens 24:2277-84. 2006..CONCLUSIONS: The reduction of urinary albumin excretion was linked to the preserved glomerular filtration rate and to adequate blood pressure control... - Physician attitudes to blood pressure control: findings from the Supporting Hypertension Awareness and Research Europe-wide surveyJosep Redon
Hospital Clinico, University of Valencia, Valencia, Spain
J Hypertens 29:1633-40. 2011..The Supporting Hypertension Awareness and Research Europe-wide (SHARE) physician survey aimed to qualify the key challenges that physicians face when trying to get patients to blood pressure (BP) goal... - [Prevalence of atrial fibrillation in the Spanish population aged 60 years or more. The PREV-ICTUS study]Luis Cea Calvo
Departamento de Investigación Clínica, Merck Sharp and Dohme de Espana, Madrid, Spain
Rev Esp Cardiol 60:616-24. 2007..The aims of this study were to determine the prevalence of atrial fibrillation in individuals aged 60 years or more in Spain using a random sample of the population and to identify associated factors... - Special considerations for antihypertensive agents in dialysis patientsJosep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia, Valencia, Spain
Blood Purif 29:93-8. 2010..Thus, antihypertensive regimens should preferably be based on these classes of drugs, alone or in combination. Other antihypertensive drug classes can play a complementary role... - The impact of the degree of obesity on the discrepancies between office and ambulatory blood pressure values in youthEmpar Lurbe
Pediatric Nephrology and Cardiovascular Risk Unit, Consorcio Hospital General, University of Valencia, RECAVA, Spain
J Hypertens 24:1557-64. 2006..The impact of different degrees of obesity on BP and heart rate variability was also investigated... - Discordant response of glutathione and thioredoxin systems in human hypertension?Maria L Mansego
Laboratorio de Estudios Genéticos Fundación para la Investigación del Hospital Clínico, Valencia, Spain
Antioxid Redox Signal 9:507-14. 2007..We noted a discordant response of the glutathione and thioredoxin systems in essential hypertension and to antihypertensive treatment. Further studies examining the significance of these thiols in hypertension outcomes are warranted... - Xanthine oxidoreductase polymorphisms: influence in blood pressure and oxidative stress levelsFelipe J Chaves
Genetic Studies Laboratory, Research Foundation of Clinic University Hospital of Valencia, Valencia, Spain
Pharmacogenet Genomics 17:589-96. 2007..We analyzed the association between the -337GA and 565+64CT polymorphisms of the xanthine oxidoreductase gene with blood pressure and oxidative stress levels... - Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish populationSergio Martinez-Hervas
Service of Endocrinology and Nutrition, Hospital Clinico Universitario de Valencia, Department of Medicine, University of Valencia, Valencia, Spain
Eur J Clin Invest 42:171-8. 2012..Our aim was to investigate the possible association of genetic variations of the gene codifying the UCP2 protein with obesity and fat distribution... - First-year blood pressure increase steepest in low birthweight newbornsEmpar Lurbe
Pediatric Nephrology and Cardiovascular Risk Unit, Departement of Pediatrics, Consorcio Hospital General, University of Valencia, Avda Tres Cruces s n, 46014 Valencia, Spain
J Hypertens 25:81-6. 2007..The present research has been undertaken prospectively to study the impact of birthweight and growth pattern on blood pressure changes from birth through the first year of life... - Diagnosis and treatment of hypertension in childrenEmpar Lurbe
Cardiovascular Risk Unit, Hospital General, University of Valencia, Avda Tres cruces 2, 46014 Valencia, Spain
Curr Hypertens Rep 12:480-6. 2010..In the case of secondary hypertension, pharmacologic treatment usually is required. In essential hypertension, assessment of early organ damage provides a useful tool for treatment decisions... - Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemiaJose T Real
Service of Endocrinology and Nutrition, Hospital Clinico Universitario, Department of Medicine, University of Valencia, 46010 Valencia, Spain
Metabolism 59:293-8. 2010..These data show an important alteration of OS regulation in FH and the absence of antioxidant response in CMCs mediated by some of the major antioxidant enzymes... - Safety and efficacy of low blood pressures among patients with diabetes: subgroup analyses from the ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial)Josep Redon
CIBEROBN, Institute of Health Carlos III, Hospital Clinico Universitario, INCLIVA, Valencia, Spain
J Am Coll Cardiol 59:74-83. 2012.... - Impact of cardiovascular risk factors on oxidative stress and DNA damage in a high risk Mediterranean populationMarta Fandos
Department of Biochemistry and Molecular Biology, Faculty of Medicine, School of Medicine, University of Valencia, Valencia, Spain
Free Radic Res 43:1179-86. 2009..Among the main cardiovascular risk factors, hypertension was the strongest determinant of oxidative stress in high risk subjects studied at a primary prevention stage... - Management of high blood pressure in children and adolescents: recommendations of the European Society of HypertensionEmpar Lurbe
Department of Pediatrics, Consorcio Hospital General, University of Valencia, Spain
J Hypertens 27:1719-42. 2009.... - Hypertension in the metabolic syndrome: summary of the new position statement of the European Society of HypertensionJosep Redon
Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, Valencia, Spain
Pol Arch Med Wewn 119:255-60. 2009..The effect of particular antihypertensive drugs on other components of the MS is an important clinical issue with consequences for the success of the treatment... - Long-term impact of systolic blood pressure and glycemia on the development of microalbuminuria in essential hypertensionJose Maria Pascual
Hypertension Clinics, Sagunto Hospital, University of Valencia, Valencia, Spain
Hypertension 45:1125-30. 2005..In mild hypertensives, the development of microalbuminuria was linked to insufficient blood pressure control and to a progressive increment of glucose values... - Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dG), a reliable oxidative stress marker in hypertensionOlga Espinosa
Oxidative Pathology Unit, Department of Biochemistry and Molecular Biology, School of Medicine, University of Valencia, Valencia, Spain
Free Radic Res 41:546-54. 2007..Moreover, urinary excretion of 8-oxo-dG also correlates with the GSSG/GSH ratio of cells. Conclusion: urine 8-oxo-dG assay is a good marker for monitoring oxidative stress changes in hypertensives... - Factors associated with therapeutic inertia in hypertension: validation of a predictive modelJosep Redon
Unidad de Hipertension, Servicio de Medicina Interna, Hospital Clinico, Universidad de Valencia y CIBERON, Instituto de Salud Carlos III, Madrid, Spain
J Hypertens 28:1770-7. 2010.... - The impact of birth weight on pulse pressure during adolescenceEmpar Lurbe
Pediatric Nephrology Unit, Department of Paediatrics, General Hospital, University of Valencia, Spain
Blood Press Monit 9:187-92. 2004..The objective was to study the influence of birth weight on office and ambulatory pulse pressure... - Genetic bases of urinary albumin excretion and related traits in hypertensionFernando Martinez
Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, Avda Blasco Ibanez, 17, E 46010 Valencia, Spain
J Hypertens 28:213-25. 2010..Combined strategies can contribute toward a better understanding of the genetic basis of urinary albumin excretion and renal damage in hypertension.. - Association of a mineralocorticoid receptor gene polymorphism with hypertension in a Spanish populationFernando Martinez
Hypertension Clinic, Hospital Clinico Universitario, University of Valencia, Valencia, Spain
Am J Hypertens 22:649-55. 2009..To assess the association of polymorphisms and haplotypes of the mineralocorticoid receptor (MR) (NR3C2) gene to the risk of essential hypertension (HTN) in a Spanish population... - Stroke mortality and trends from 1990 to 2006 in 39 countries from Europe and Central Asia: implications for control of high blood pressureJosep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia INCLIVA and CIBERObn Institute of Health Carlos III, Avda Blasco Ibanez, 17, 46010 Madrid, Spain
Eur Heart J 32:1424-31. 2011.... - Effectiveness of an Interventional Program to Improve Blood Pressure Control in Hypertensive Patients at High Risk for Developing Heart Failure: HEROIC studyBeatriz de Rivas
Medical Department, AstraZeneca, Madrid, Spain
J Clin Hypertens (Greenwich) 12:335-44. 2010..More complex and intensive programs are needed for this type of prevention... - Antihypertensive activity of angiotensin II AT1 receptor antagonists: a systematic review of studies with 24 h ambulatory blood pressure monitoringMaria Jose Fabia
Hypertension Clinic, Internal Medicine, Hospital Clinico Universitario, Universidad de Valencia, Valencia, Spain
J Hypertens 25:1327-36. 2007..To perform a systematic review of the antihypertensive activity of the angiotensin II AT1 receptor antagonists (ARB)... - The metabolic syndrome in hypertension: diagnostic and therapeutic implicationsJosep Redon
Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, 46010 Valencia, Spain
Curr Hypertens Rep 9:305-13. 2007..The impact of particular antihypertensive drugs on other components of the metabolic syndrome is an important clinical issue with consequences for the success of treatment... - Nocturnal blood pressure and progression to end-stage renal disease or death in nondiabetic chronic kidney disease stages 3 and 4Josep Redon
Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, Valencia, Spain
J Hypertens 28:602-7. 2010..The objective was to assess the role of office and ambulatory blood pressure (BP) on the development of end-stage renal disease (ESRD) in nondiabetic chronic renal failure... - Blood pressure control and stroke mortality across populationsJosep Redon
Hypertension Clinic, Internal Medicine Department, Hospital Clinico, University of Valencia, 46010 Valencia, Spain
Curr Hypertens Rep 9:440-1. 2007 - Antihypertensive treatment: should it be titrated to blood pressure reduction or to target organ damage regression?Josep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia, Avda Blasco Ibanez 17, 46010 Valencia, Spain
Curr Opin Nephrol Hypertens 14:448-52. 2005..Moreover, monitoring intermediate objectives may provide scientific evidence for delineating the best antihypertensive treatment... - Predictors of progression in hypertensive renal disease in childrenEmpar Lurbe
Pediatric Nephrology Unit, Hospital General, University of Valencia, Avenida Tres Cruces s n, 46014 Valencia, Spain
J Clin Hypertens (Greenwich) 6:186-91. 2004..It should be reduced as much as possible to obtain maximal renoprotective effect. The role of the other factors, such as lipid disorders and genetics, remains elusive... - Factors related to the occurrence of microalbuminuria during antihypertensive treatment in essential hypertensionJosep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia, Valencia, Spain
Hypertension 39:794-8. 2002.... - Urinary albumin excretion and glomerular filtration rate across the spectrum of glucose abnormalities in essential hypertensionJosep Redon
Hypertension Clinic, Internal Medicine Service, Hospital Clinico, University of Valencia, 46010 Valencia, Spain
J Am Soc Nephrol 17:S236-45. 2006..29 to 2.04). There is a close relationship between abnormal UAE and renal insufficiency in essential hypertension. This is more marked in patients with diabetes and moderate in patients with high-range impaired fasting glucose... - Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish populationMaria Luisa Mansego
Genotyping and Genetic Diagnosis Unit, Fundación de Investigación del Hospital Clínico de Valencia INCLIVA, Valencia, Spain
PLoS ONE 7:e31853. 2012..The association was replicated in a second population in which HOMA index was also evaluated... - Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetesEmpar Lurbe
Pediatric Nephrology Unit, Department of Pediatrics, Hospital General and University of Valencia, Valencia, Spain
N Engl J Med 347:797-805. 2002..In those whose blood pressure during sleep decreases normally, the progression from normal albumin excretion to microalbuminuria appears to be less likely... - Birth weight impacts on wave reflections in children and adolescentsEmpar Lurbe
Pediatric Nephrology Unit, Department of Pediatrics, General Hospital, University of Valencia, Avda Tres Cruces s n, 46014 Valencia, Spain
Hypertension 41:646-50. 2003..These early alterations may be amplified throughout life and may contribute to the increased cardiovascular risk associated with low birth weight... - Cardiovascular risk reduction by reversing endothelial dysfunction: ARBs, ACE inhibitors, or both? Expectations from the ONTARGET Trial ProgrammeLuis Miguel Ruilope
Servicio de Nefrologia, Unidad de Hipertension Hospital, 12 de Octubre, Madrid, Spain
Vasc Health Risk Manag 3:1-9. 2007..Completion of ONTARGET is expected in 2008... - Development of microalbuminuria in essential hypertensionJosep Redon
Hypertension Clinic, Internal Medicine, Hospital Clinico, Avda Blasco Ibanez, 17, 46010 Valencia, Spain
Curr Hypertens Rep 8:171-7. 2006..Whether or not the multiple approaches need to be implemented from the beginning or step by step in an individual approach should be established in the near future... - Managing resistant hypertension: not just a question of numbersJosep Redon
Hypertension Clinic, Internal Medicine, , RECAVA, University of Valencia, Valencia, Spain
Am J Hypertens 18:1541-2. 2005 - Inadequate cytoplasmic antioxidant enzymes response contributes to the oxidative stress in human hypertensionFelipe J Chaves
Research Unit, Hospital Clinico Universitario, University of Valencia, Avenida Blasco Ibañez 17, 46010 Valencia, Spain
Am J Hypertens 20:62-9. 2007..The inadequate response of the main cytoplasmatic antioxidant systems, as well as of the enzymes participating in the maintenance of glutathione levels, may contribute to the vulnerability of hypertensives to oxidative stress... - Efficacy in angiotensin receptor blockade: a comparative review of data with olmesartanJosep Redon
Hypertension Clinic, Hospital Clinico Universitario, University of Valencia, Valencia, Spain
J Renin Angiotensin Aldosterone Syst 10:147-56. 2009.... - Uncontrolled early morning blood pressure in medicated patients: the ACAMPA study. Analysis of the Control of Blood Pressure using Abulatory Blood Pressure MonitoringJosep Redon
Hypertension Clinic, Hospital Clinico, University of Valencia, Valencia, Spain
Blood Press Monit 7:111-6. 2002..The objective of this study was thus to assess the blood pressure behaviour profile of early morning blood pressure in patients receiving antihypertensive treatment... - [Risk assessment for a first stroke in Spanish hypertensive population in primary care. The ERIC-HTA study]Jose V Lozano
Centro de Salud Serrería 2, Valencia, Spain
Med Clin (Barc) 125:247-51. 2005..Stroke is a major cause of morbidity and mortality in hypertensive population. The aim of this study is to estimate the 10-year risk of a first stroke in Spanish hypertensive population using the Framingham scale...