Research Topics
| Michael L TressSummaryCountry: Spain Publications
| Collaborators
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Detail Information
Publications
SQUARE--determining reliable regions in sequence alignmentsMichael L Tress
CNB CSIC, Calle Darwin, Cantoblanco, 28049 Madrid, Spain
Bioinformatics 20:974-5. 2004..In addition, the scores can be compared against template secondary structure, conserved residues and important sites...
Predicting reliable regions in protein alignments from sequence profilesMichael L Tress
Protein Design Group, Centro Nacional de Biotechnologia, CNB CSIC, Cantoblanco, 28049 Madrid, Spain
J Mol Biol 330:705-18. 2003..This suggests that many binding sites that are present in both target and template sequences are in sequence-conserved regions and that there is the possibility of translating reliability to binding site prediction...
An analysis of the Sargasso Sea resource and the consequences for database compositionMichael L Tress
Protein Design Group, CNB CSIC, Calle Darwin, Cantoblanco 28049 Madrid, Spain
BMC Bioinformatics 7:213. 2006....
firestar--prediction of functionally important residues using structural templates and alignment reliabilityGonzalo Lopez
Structural Biology and Biocomputing Program, Spanish National Cancer Research Centre CNIO Melchor Fernández Almagro, 3, E 28029, Madrid, Spain
Nucleic Acids Res 35:W573-7. 2007..We found this facility particularly useful during the recent assessment of CASP7 function prediction. Availability: http://firedb.bioinfo.cnio.es/Php/FireStar.php...
Assessment of intramolecular contact predictions for CASP7Jose M G Izarzugaza
Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, 3E 28029 Madrid, Spain
Proteins 69:152-8. 2007..In general, contacts inferred from 3D structural predictions are similar in accuracy to those predicted by contact prediction methods. However, contact prediction methods were more accurate for some targets...
The implications of alternative splicing in the ENCODE protein complementMichael L Tress
Structural Computational Biology Programme, Spanish National Cancer Research Centre, E 28029 Madrid, Spain
Proc Natl Acad Sci U S A 104:5495-500. 2007....
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectEwan Birney
Nature 447:799-816. 2007..Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function...
Determination and validation of principal gene productsMichael L Tress
Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, Madrid, Spain
Bioinformatics 24:11-7. 2008..The pipeline was able to determine a principal isoform for 83% of a set of well-annotated genes with multiple variants...
