Elena Sancho

Summary

Country: Spain

Publications

  1. ncbi Signaling pathways in intestinal development and cancer
    Elena Sancho
    Institut de Recerca Biomedica de Barcelona IRBB PCB, Parc Cientific de Barcelona, 08028 Barcelona, Spain
    Annu Rev Cell Dev Biol 20:695-723. 2004
  2. ncbi The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    Marc van de Wetering
    Department of Immunology and Center for Biomedical Genetics, University Medical Center, 3584 CX, Utrecht, The Netherlands
    Cell 111:241-50. 2002
  3. ncbi Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
    Eduard Batlle
    Department of Immunology and Center for Biomedical Genetics, University Medical Center, Utrecht, The Netherlands
    Cell 111:251-63. 2002
  4. ncbi Live and let die in the intestinal epithelium
    Elena Sancho
    Centre for Biomedical Genetics, Hubrecht Laboratorium, Koninklijke Nederlandse Akademie van Wetenschappen, Utrecht, The Netherlands
    Curr Opin Cell Biol 15:763-70. 2003
  5. ncbi EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells
    Carme Cortina
    Oncology Programme, Institute for Research in Biomedicine IRB, Josep Samitier 1 5, 08028 Barcelona Spain
    Nat Genet 39:1376-83. 2007

Collaborators

  • Hans Clevers
  • Eduard Batlle
  • Marc van de Wetering
  • Carme Cortina
  • Mar Iglesias
  • Sergio Palomo-Ponce
  • Gavin Whissell
  • Mireia Humà
  • Lourdes Gallego
  • Juan Luis Fernández-Masip
  • Ana Vivancos
  • Nerea Peiró
  • Alice Davy
  • Suzanne Jonkheer
  • Josep Lloreta
  • Karin van der Horn
  • Tony Pawson
  • Jan Meeldijk
  • Rene Medema
  • Anna Pavlina Haramis
  • Gwen Soete
  • Damien Coudreuse
  • Adam Hurlstone
  • Maaike van den Born
  • Irma Oving
  • Harry Beghtel
  • Martin Eilers
  • Wim de Lau
  • Cornelis Verweij
  • Petra Moerer
  • Jeffrey T Henderson
  • Jennifer Robertson
  • Gerwin Huls
  • Steven Pals
  • Maaike M W van den Born
  • Menno Tjon-Pon-Fong

Detail Information

Publications5

  1. ncbi Signaling pathways in intestinal development and cancer
    Elena Sancho
    Institut de Recerca Biomedica de Barcelona IRBB PCB, Parc Cientific de Barcelona, 08028 Barcelona, Spain
    Annu Rev Cell Dev Biol 20:695-723. 2004
    ..Here, we integrate recent knowledge of the molecular inner workings of the prototype signaling cascades with their specific roles in intestinal epithelial homeostasis and in neoplastic transformation of the epithelium...
  2. ncbi The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    Marc van de Wetering
    Department of Immunology and Center for Biomedical Genetics, University Medical Center, 3584 CX, Utrecht, The Netherlands
    Cell 111:241-50. 2002
    ..Thus, the beta-catenin/TCF-4 complex constitutes the master switch that controls proliferation versus differentiation in healthy and malignant intestinal epithelial cells...
  3. ncbi Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
    Eduard Batlle
    Department of Immunology and Center for Biomedical Genetics, University Medical Center, Utrecht, The Netherlands
    Cell 111:251-63. 2002
    ..We conclude that in the intestinal epithelium beta-catenin and TCF couple proliferation and differentiation to the sorting of cell populations through the EphB/ephrin-B system...
  4. ncbi Live and let die in the intestinal epithelium
    Elena Sancho
    Centre for Biomedical Genetics, Hubrecht Laboratorium, Koninklijke Nederlandse Akademie van Wetenschappen, Utrecht, The Netherlands
    Curr Opin Cell Biol 15:763-70. 2003
    ..Wnt signalling appears to control most of these events...
  5. ncbi EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells
    Carme Cortina
    Oncology Programme, Institute for Research in Biomedicine IRB, Josep Samitier 1 5, 08028 Barcelona Spain
    Nat Genet 39:1376-83. 2007
    ..Our results indicate that CRC cells must silence EphB expression to avoid repulsive interactions imposed by normal ephrin-B1-expressing intestinal cells at the onset of tumorigenesis...