Research Topics
| Manuel MuñozSummaryCountry: Spain Publications
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Publications
Oral trasmucosal ferric carboxymaltose for the treatment of iron-deficiency anemiaManuel Muñoz
University of Malaga, School of Medicine, Transfusion Medicine, 29071 Malaga, Spain
Expert Opin Pharmacother 13:907-21. 2012..There are, however, some aspects (such as hypophosphatemia) and important missing information (such as use in children and pregnant women) that need to be addressed for facilitating a widespread use of FCM...
Role of parenteral iron in transfusion requirements after total hip replacement. A pilot studyM Munoz
GIEMSA, School of Medicine, University of Malaga, Malaga, Spain
Transfus Med 16:137-42. 2006..017). Postoperative parenteral iron administration could be a safe and effective way to reduce ABT requirements in the THR patients. A large, randomized controlled trial to confirm these results is warranted...
Which patients are more likely to benefit from postoperative shed blood salvage after unilateral total knee replacement? An analysis of 581 consecutive proceduresM Munoz
GIEMSA, School of Medicine, University of Malaga, Campus de Teatinos s n, 19071 Málaga, Spain
Vox Sang 92:136-41. 2007..We evaluated that patients are more likely to benefit of USB reinfusion after TKR...
[Prevalence and treatment of anemia in critically ill patients]M Munoz
Medicina Transfusional, Facultad de Medicina, Malaga, and Servicio de Cuidados Intensivos y Urgencias, Hospital Universitario Virgen del Rocio, Sevilla, Spain
Med Intensiva 31:388-98. 2007....
Efficacy and safety of intravenous iron therapy as an alternative/adjunct to allogeneic blood transfusionM Munoz
Transfusion Medicine, School of Medicine, University of Malaga, Malaga, Spain
Vox Sang 94:172-83. 2008..Nonetheless, this also indicates the need for further large, randomized controlled trials on the safety and efficacy of intravenous iron for the treatment of anaemia in different clinical settings...
Blood conservation strategies in major orthopaedic surgery: efficacy, safety and European regulationsM Munoz
GIEMSA, Medicina Transfusional, University of Malaga, Malaga, Spain
Vox Sang 96:1-13. 2009....
An update on iron physiologyManuel Muñoz
Transfusion Medicine, School of Medicine, University of Malaga, Malaga 29071, Spain
World J Gastroenterol 15:4617-26. 2009..Laboratory tests provide evidence of iron depletion in the body, or reflect iron-deficient red cell production. The appropriate combination of these laboratory tests help to establish a correct diagnosis of ID status and anemia...
Intravenous iron in inflammatory bowel diseaseManuel Muñoz
Transfusion Medicine, School of Medicine, University of Malaga, Malaga 29071, Spain
World J Gastroenterol 15:4666-74. 2009....
Iron deficiency and anaemia in bariatric surgical patients: causes, diagnosis and proper managementM Munoz
School of Medicine, University of Malaga, Malaga, Spain
Nutr Hosp 24:640-54. 2009..New IV preparations, such ferric carboxymaltose, are safe, easy to use and up to 1000 mg can be given in a single session, thus providing an excellent tool to avoid or treat iron deficiency in this patient population...
Sedimentation method for preparation of postoperatively salvaged unwashed shed blood in orthopaedic surgeryM Munoz
Transfusion Medicine, School of Medicine, University of Malaga, Campus de Teatinos, 29071 Malaga, Spain
Br J Anaesth 105:457-65. 2010..We evaluated a colloid-based sedimentation method for improving and standardizing the quality of USB collected after TKR without the need for washing...
Disorders of iron metabolism. Part 1: molecular basis of iron homoeostasisManuel Muñoz
Transfusion Medicine, School of Medicine, University of Malaga, Malaga, Spain
J Clin Pathol 64:281-6. 2011..It binds ferroportin on enterocytes, macrophages and hepatocytes triggering its internalisation and lysosomal degradation. Inappropriate hepcidin secretion may lead to either iron deficiency or iron overload...
Disorders of iron metabolism. Part II: iron deficiency and iron overloadManuel Muñoz
Transfusion Medicine, School of Medicine, University of Malaga, Malaga, Spain
J Clin Pathol 64:287-96. 2011..REVIEW OF TREATMENT OPTIONS: Indications, advantages and side effects of the different options for treating iron overload (phlebotomy and iron chelators) and iron deficiency (oral or intravenous iron formulations) will be discussed...
Post-operative unwashed shed blood transfusion does not modify the cellular immune response to surgery for total knee replacementM Munoz
GIEMSA, School of Medicine, University of Malaga, Malaga, Spain
Acta Anaesthesiol Scand 50:443-50. 2006..We evaluated the impact of USB return on the cellular immune response (CIR) after TKR...
Impact of postoperative unwashed shed blood retrieved after total knee arthroplasty on endotoxin-stimulated tumor necrosis factor alpha release in vitroManuel Muñoz
Department of Biochemistry and Immunology, School of Medicine, Campus de Teatinos, University of Malaga, 29071 Malaga, Spain
Anesthesiology 104:267-72. 2006..Therefore, the authors explored the effects of USB on the mitogen-driven cytokine synthesis by the patient's peripheral blood mononuclear cells...
[Ability of leukocyte reduction filters to remove fat particles from blood in experimental models simulating blood salvage in orthopedic surgery]M Muñoz Gómez
GIEMSA, Facultad de Medicina, Universidad de Malaga
Rev Esp Anestesiol Reanim 52:81-7. 2005..Therefore, this study was initiated to ascertain the capacity of leukocyte filters to remove FP using in vitro models...
Transfusion of post-operative shed blood: laboratory characteristics and clinical utilityM Munoz
Department of Biochemistry and Molecular Biology, School of Medicine, University of Malaga, Malaga, Spain
Eur Spine J 13:S107-13. 2004....
Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidineM Munoz
GIEMSA, Department of Biochemistry, School of Medicine, University of Malaga, Malaga, Spain
Eur Spine J 13:367-73. 2004..However, further research is needed to determine the best dose and timing of preoperative treatment administration, and to correlate these changes with long-term clinical results...
Utility of point-of-care haemoglobin measurement in the HemoCue-B haemoglobin for the initial diagnosis of anaemiaM Munoz
Department of Biochemistry and Molecular Biology, School of Medicine, University of Malaga, Malaga, Spain
Clin Lab Haematol 27:99-104. 2005..4%; sensitivity, 96.5%). Compared with ABX, HBH provides accurate and precise measurements for a wide range of Hb and its use in primary health care seems to be a good method for the initial diagnosis of anaemia...
Iron metabolism, inflammation and anemia in critically ill patients. A cross-sectional studyM Munoz
GIEMSA Department of Biochemistry and Molecular Biology, School of Medicine, University of Malaga, Spain
Nutr Hosp 20:115-20. 2005....
[Precision and accuracy of the immediate determination of hemoglobin using HemoCueB Hemoglobin in urgent, surgical, and critical patients]M Muñoz Gómez
GIEMSA, Facultad de Medicina, Universidad de Malaga
Rev Esp Anestesiol Reanim 50:332-9. 2003....
Benefits of postoperative shed blood reinfusion in patients undergoing unilateral total knee replacementManuel Muñoz
GIEMSA, School of Medicine, University of Malaga, Campus de Teatinos, S N, 29071, Malaga, Spain
Arch Orthop Trauma Surg 125:385-9. 2005..We have, therefore, evaluated the clinical utility of USB return in TKR patients, with a special focus on patients with mild anaemia...
[Evaluation of the OrthoPAT autologous transfusion system by experimental models simulating intra- and postoperative blood salvage]M Muñoz Gómez
GIEMSA, Facultad de Medicina Servicios de Anestesiología, Hospital Clinico Universitario Virgen de la Victoria, Malaga
Rev Esp Anestesiol Reanim 52:321-7. 2005..To evaluate the efficacy of the OrthoPAT (Haemonetics) system for blood salvage and for removing chemical or cellular debris, by experimental models simulating intra- and postoperative conditions...
Impact of postoperative shed blood transfusion, with or without leucocyte reduction, on acute-phase response to surgery for total knee replacementM Munoz
Department of Clinical Chemistry, GIEMSA, School of Medicine, Univeristy of Malaga, Malaga, Spain
Acta Anaesthesiol Scand 49:1182-90. 2005..We evaluated the impact of USB return, with or without leucocytes, on the acute-phase response (APR) after TKR...
[Usefulness of the administration of intravenous iron sucrose for the correction of preoperative anemia in major surgery patients]Manuel Muñoz
Departamento de Medicina Transfusional, Facultad de Medicina, Universidad de Malaga, Malaga, Espana
Med Clin (Barc) 132:303-6. 2009..We evaluated the efficacy of intravenous iron sucrose (IVIS) administration for correction of anemia in these patient populations...
[Is there still a role for recombinant erythropoietin in the management of anaemia of critical illness?]Manuel Muñoz
Medicina Transfusional, Facultad de Medicina, Universidad de Malaga, Malaga, Espana
Med Clin (Barc) 132:749-55. 2009..Consequently, more basic and clinical studies are required to ascertain which patients are more likely to benefit from these treatments, as well as to identify the optimal doses and administration schedules, and iron administration...
Role of training activities for the reduction of pre-analytical errors in laboratory samples from primary careAdolfo Romero
Unidad de Gestión Clínica de Hematología y Laboratorio, Hospital Universitario Virgen de la Victoria, Malaga, Spain
Clin Chim Acta 413:166-9. 2012..The first of these has been the realization of a cycle of educational sessions for PC nurses, followed by the evaluation of their impact on PE number...
Preanalytical mistakes in samples from primary care patientsAdolfo Romero
Clinical Laboratory, University Hospital Virgen de la Victoria, Malaga, Spain
Clin Chem Lab Med 47:1549-52. 2009..We detected PAMs in samples from Primary Health Care Centres (PHCC) served by our central laboratory. Thus, the goal of this study was to describe the number and types of PAMs, and to suggest some strategies for improvement...
[Incidence and mortality of massive transfusion in a university hospital: study of the period 2001-2005]Arturo Campos
Servicio de Hematologia y Hemoterapia, Hospital Universitario Virgen de la Victoria, Malaga, Espana
Med Clin (Barc) 129:366-71. 2007..We, therefore, retrospectively assessed the incidence of MT at our institution (a 700-bed university hospital) during a 5-year period...
Length of sedimentation reaction in blood: a comparison of the test 1 ESR system with the ICSH reference method and the sedisystem 15Adolfo Romero
Department of Haematology, H.C.U. Virgen de la Victoria, , Spain
Clin Chem Lab Med 41:232-7. 2003..In addition, due to its operational characteristics (60 samples/20 min) it is a suitable tool for clinical laboratories with a high work load as well as for emergency laboratories...
