Research Topics
| Raquel MoralSummaryCountry: Spain Publications
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Publications
In utero exposure to butyl benzyl phthalate induces modifications in the morphology and the gene expression profile of the mammary gland: an experimental study in ratsRaquel Moral
Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Environ Health 10:5. 2011..The aim of this study was to elucidate the effect of prenatal exposure to BBP on the morphology, proliferative index, and genomic signature of the rat mammary gland at different ages...
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposureRaquel Moral
Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
BMC Genomics 8:453. 2007....
Genomic signature induced by pregnancy in the human breastGabriela A Balogh
Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Oncol 28:399-410. 2006....
Molecular basis of pregnancy-induced breast cancer protectionJose Russo
Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Eur J Cancer Prev 15:306-42. 2006..This is a novel concept that challenges the current knowledge that a chemopreventive agent needs to be given for a long period to suppress a metabolic pathway or abrogate the function of an organ...
Effect of prenatal exposure to the endocrine disruptor bisphenol A on mammary gland morphology and gene expression signatureRaquel Moral
Breast Cancer Research Laboratory, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, Pennsylvania 19111, USA
J Endocrinol 196:101-12. 2008..The increase of undifferentiated structures and the changes in the gene expression profile at different ages suggest that prenatal exposure to BPA can affect the susceptibility of the mammary gland to transformation...
The concept of stem cell in the mammary gland and its implication in morphogenesis, cancer and preventionJose Russo
Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Front Biosci 11:151-72. 2006....
Molecular mechanisms of the effects of olive oil and other dietary lipids on cancerEduard Escrich
Department of Cell Biology, Physiology and Immunology, Medical Physiology Unit, Faculty of Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain
Mol Nutr Food Res 51:1279-92. 2007....
Modulatory effects and molecular mechanisms of olive oil and other dietary lipids in breast cancerEduard Escrich
Department of Cell Biology, Physiology and Immunology, Medical Physiology Unit, Medicine School, Universitat Autonoma de Barcelona, Spain
Curr Pharm Des 17:813-30. 2011..This article will explore the current knowledge of these mechanisms, including our own results in the context of the international literature...
The protective role of pregnancy in breast cancerJose Russo
Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Breast Cancer Res 7:131-42. 2005....
High-fat corn oil diet promotes the development of high histologic grade rat DMBA-induced mammary adenocarcinomas, while high olive oil diet does notIrmgard Costa
Department of Cell Biology, Physiology and Immunology, Physiology Unit, Medical School, , Barcelona, Spain
Breast Cancer Res Treat 86:225-35. 2004..As far as we are concerned, a similar histopathologic approach of the effects of the dietary lipids on experimental breast cancer has not been carried out up to now...
Influence of DMBA-induced mammary cancer on the liver CPT I, mit HMG-CoA synthase and PPARalpha mRNA expression in rats fed a low or high corn oil dietRaquel Moral
Department of Cell Biology, Physiology and Immunology, Medical Physiology Unit, School of Medicine, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
Int J Mol Med 14:283-7. 2004..This effect of the cancer state could be related to tumor aggressiveness and suggest a preferential redirection of long-chain fatty acids into energetic and specific pathways of the cancer cells...
Identification of novel differentially expressed genes by the effect of a high-fat n-6 diet in experimental breast cancerEduard Escrich
Department of Cell Biology, Physiology and Immunology, Physiology Unit, Medical School, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
Mol Carcinog 40:73-8. 2004....
High corn oil and high extra virgin olive oil diets have different effects on the expression of differentiation-related genes in experimental mammary tumorsRaquel Moral
Department of Cell Biology, Physiology and Immunology, Medical School, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
Oncol Rep 20:429-35. 2008..The modulation of transferrin and ZBP1 expression by the high olive oil and the high corn oil diets could be one of the mechanisms by which such diets have a different influence on mammary carcinogenesis...
Modulation of EGFR and neu expression by n-6 and n-9 high-fat diets in experimental mammary adenocarcinomasRaquel Moral
Department of Cell Biology, Physiology and Immunology, Physiology Unit, Medical School, , 08193 Bellaterra Barcelona, Spain
Oncol Rep 10:1417-24. 2003....
Effects of a high olive oil diet on the clinical behavior and histopathological features of rat DMBA-induced mammary tumors compared with a high corn oil dietMontserrat Solanas
Department of Cell Biology, Physiology and Immunology, Medical Physiology Unit, Medical School, , 08193 Bellaterra, Barcelona, Spain
Int J Oncol 21:745-53. 2002....
