Research Topics
Species | A J LucendoSummaryCountry: Spain Publications
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Publications
An update on the immunopathogenesis of eosinophilic esophagitisAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, S N, 13700 Tomelloso, Spain
Expert Rev Gastroenterol Hepatol 4:141-8. 2010..This article reviews recent advances in the immunopathogenesis of EoE, which should also consider other pathways to activate the esophageal mucosal immune system...
Eosinophilic esophagitis in adults: an emerging diseaseAlfredo J Lucendo
Department of Gastroenterology, Hospital Universitario La Paz, , Madrid, Spain
Dig Dis Sci 49:1884-8. 2004
Eosinophilic esophagitis -- clinical manifestations, diagnosis, and treatmentA J Lucendo Villarín
Department of Digestive Diseases, Complejo Hospitalario La Mancha Centro, General Hospital of Tomelloso, Alcázar de San Juan Tomelloso, Ciudad Real, Spain
Rev Esp Enferm Dig 101:49-59. 2009..Drug use is standard, particularly involving topical steroids, which may revert manifestations and histological lesions, even though recurrence following discontinuation is common...
Importance of nutrition in inflammatory bowel diseaseAlfredo José Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, s n 13700 Tomelloso, Ciudad Real, Spain
World J Gastroenterol 15:2081-8. 2009..Nutritional support is especially important in childhood IBD as an alternative to pharmacological treatment. This report discusses the complex relationship between diet and IBD...
Eosinophilic diseases of the gastrointestinal tractAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Ciudad Real, Spain
Scand J Gastroenterol 45:1013-21. 2010..The physiopathological bases of these entities need to be established in order to define specific treatment aimed at preventing and altering their clinical evolution...
Adult patients with eosinophilic esophagitis do not show an increased frequency of the HLA-DQ2/DQ8 genotypes predisposing to celiac diseaseAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, S N, 13700, Tomelloso, Ciudad Real, Spain
Dig Dis Sci 56:1107-11. 2011..Recent articles have described patients that share eosinophilic esophagitis (EoE) and celiac disease (CD) suggesting a true relationship between both diseases...
Boerhaave's syndrome as the primary manifestation of adult eosinophilic esophagitis. Two case reports and a review of the literatureA J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Ciudad Real, Spain
Dis Esophagus 24:E11-5. 2011..Therefore, patients with non-traumatic Boerhaave's syndrome should be assessed for EoE, especially if they are young men who have a prior history of dysphagia and allergic manifestations...
Esophageal manifestations of celiac diseaseA J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Ciudad Real, Spain
Dis Esophagus 24:470-5. 2011..Recent studies have suggested the existence of a possible relationship between CD and eosinophilic esophagitis, which should be more deeply investigated...
Montelukast was inefficient in maintaining steroid-induced remission in adult eosinophilic esophagitisAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, S N, 13700, Tomelloso, Ciudad Real, Spain
Dig Dis Sci 56:3551-8. 2011....
Subepithelial collagen deposition, profibrogenic cytokine gene expression, and changes after prolonged fluticasone propionate treatment in adult eosinophilic esophagitis: a prospective studyAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Spain
J Allergy Clin Immunol 128:1037-46. 2011..However, limited data are available on the intensity and reversibility of fibrous remodeling in adults with EoE...
The role of mast cells in eosinophilic esophagitisAlfredo J Lucendo
Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Spain
Pediatr Allergy Immunol 20:512-8. 2009..Specific approach studies are needed to clarify the function of these cells in the physiopathology of EE, which could be a possible therapeutic target...
[Eosinophilic esophagitis. Review of current clinical and physiopathological concepts]Alfredo J Lucendo Villarín
Seccion de Aparato Digestivo, Hospital General La Mancha Centro, Alcazar de San Juan, Ciudad Real, Espana
Gastroenterol Hepatol 30:234-43. 2007..This paper aims to review the newest clinical aspects of EE and the results of studies directed at investigating the pathophysiology of the disease. Furthermore, we carry out a critical review of available therapeutic options...
Endoscopic, bioptic, and manometric findings in eosinophilic esophagitis before and after steroid therapy: a case seriesA J Lucendo
Department of Gastroenterology, Hospital Universitario La Paz, Universidad Autonoma de Madrid, Madrid, Spain
Endoscopy 39:765-71. 2007..The aim of the present case series report is to describe and classify endoscopic appearances before and after corticoid therapy in relation to histopathology and manometry...
[Eosinophilic esophagitis]Alfredo J Lucendo
Seccion de Aparato Digestivo, Complejo Hospitalario La Mancha Centro, Alcázar de San Juan Manzanares, Ciudad Real, Espana
Med Clin (Barc) 128:590-7. 2007....
Immunophenotypic characterization and quantification of the epithelial inflammatory infiltrate in eosinophilic esophagitis through stereology: an analysis of the cellular mechanisms of the disease and the immunologic capacity of the esophagusAlfredo J Lucendo
Department of Gastroenterology, Hospital Universitario La Paz, Madrid, Spain
Am J Surg Pathol 31:598-606. 2007..EE represents growth of this esophageal capacity and its pathogeny could respond to mixed cellular and humoral mechanisms...
Manometric findings in adult eosinophilic oesophagitis: a study of 12 casesAlfredo J Lucendo
Department of Gastroenterology, La Paz University Hospital, Autonoma University of Madrid, Madrid, Spain
Eur J Gastroenterol Hepatol 19:417-24. 2007..To describe the manometric findings detected in adult patients with dysphagia that were diagnosed of eosinophilic oesophagitis, and to compare with the cases of eosinophilic infiltration of the oesophagus reported in the literature...
Eosinophilic esophagitis in adults, an emerging cause of dysphagia. Description of 9 casesA J Lucendo Villarín
Service of Digestive Diseases, Hospital Universitario La Paz, Madrid, Spain
Rev Esp Enferm Dig 97:229-39. 2005..It is characterized by intense infiltration of eosinophilic leukocytes in the esophageal mucosa, without involvement of other sections of the alimentary canal...
Bruising of the esophagus as a cause of gastrointestinal bleeding in a case of heatstrokeA J Lucendo Villarín
Service of Digestive Diseases, Hospital Universitario La Paz, Madrid, Spain
Rev Esp Enferm Dig 97:596-9. 2005..Esophageal submucosal bruising is an exceptional cause of hematemesis in serious heatstroke not previously described in the literature...
Treatment with topical steroids downregulates IL-5, eotaxin-1/CCL11, and eotaxin-3/CCL26 gene expression in eosinophilic esophagitisAlfredo J Lucendo
Department of Gastroenterology, Hospital Universitario La Paz, Madrid, Spain
Am J Gastroenterol 103:2184-93. 2008....
Granular cell tumors of the esophagus: report of five cases and review of diagnostic and therapeutic techniquesL de Rezende
Department of Gastroenterology, University Hospital of the Canary Islands, Tenerife, Spain
Dis Esophagus 20:436-43. 2007....
Nutritional and dietary aspects of celiac diseaseAlvaro García-Manzanares
Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, s n 13700 Tomelloso, Ciudad Real, Spain
Nutr Clin Pract 26:163-73. 2011..In addition, certain nutrient deficiencies require specific management. This article reviews the nutritional aspects of CD and provides practical guidelines to correct these deficiencies and to ensure optimum GFD compliance...
