Research Topics
| Jerónimo CarnésSummaryAffiliation: Laboratorios LETI Country: Spain Publications
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Detail Information
Publications
New strategies for allergen immunotherapyJerónimo Carnés
Research and Development Department, Laboratorios LETI SL Madrid, Spain
Recent Pat Inflamm Allergy Drug Discov 2:92-101. 2008..The review article also discuss recent patent related to the field...
Detection of allergen composition and in vivo immunogenicity of depigmented allergoids of Betula albaJ Carnes
Research and Development Department, Laboratorios LETI S L, Calle del Sol no 5, 28760 Tres Cantos, Madrid, Spain
Clin Exp Allergy 39:426-34. 2009..Chemical modification of allergen vaccines to reduce IgE binding improves safety while maintaining clinical efficacy. However, this also complicates the characterization of allergoids using techniques as for native allergen extracts...
Usefulness of manufactured tomato extracts in the diagnosis of tomato sensitization: Comparison with the prick-prick methodAngel Ferrer
Research and Development Department, Laboratorios LETI, S, L, Tres Cantos, Madrid, Spain
Clin Mol Allergy 6:1. 2008..The objective of the study was to assess the potential diagnostic of freeze-dried extracts of Canary Islands tomatoes, comparing the wheal sizes induced by prick test with the prick-prick method...
Enzymatic activity in body and fecal extracts of the storage mite Chortoglyphus arcuatusJerónimo Carnés
Hospital Xeral de Calde, Allergology Service, Lugo, Spain
Int Arch Allergy Immunol 145:207-12. 2008..Chortoglyphus arcuatus has been described in many countries. Many allergens are potent enzymes, which may promote a Th2 immune response. The aim of this study was to evaluate the enzymatic activity of body and fecal extracts of C. arcuatus...
Identification and quantification of tomato allergens: in vitro characterization of six different varietiesM Ángeles López-Matas
R and D Department, Laboratorios LETI, SL Tres Cantos, Madrid, Spain
Ann Allergy Asthma Immunol 106:230-8. 2011..The prevalence of sensitization to tomato has been estimated in 6.5% in a Mediterranean population...
In vitro cross-reactivity between tomato and other plant allergensM Ángeles López-Matas
R and D Department, Laboratorios LETI S L, Tres Cantos, Madrid, Spain
Ann Allergy Asthma Immunol 103:425-31. 2009..Cross-reactivity among fruits and different pollen and fruit species has been extensively reported...
Seafood hypersensitivity in mite sensitized individuals: is tropomyosin the only responsible allergen?Manuel Boquete
Allergy Service, Hospital General de Calde, Lugo, Spain
Ann Allergy Asthma Immunol 106:223-9. 2011..Seafood allergy has been related to mite sensitization, mainly mediated by the muscle protein tropomyosin...
Comparison of the allergenicity and Ole e 1 content of 6 varieties of Olea europaea pollen collected during 5 consecutive yearsEnrique Fernandez-Caldas
Research and Development, Laboratorios LETI S L, Madrid, Spain
Ann Allergy Asthma Immunol 98:464-70. 2007..Numerous varieties of Olea europaea have been described in Mediterranean countries...
The use of raw or boiled crustacean extracts for the diagnosis of seafood allergic individualsJerónimo Carnés
Laboratorios LETI, S L Research Laboratories, Tres Cantos, Madrid, Spain
Ann Allergy Asthma Immunol 98:349-54. 2007..Seafood plays an important role in human nutrition and is responsible for severe hypersensitivity reactions...
Enzymatic activity of Dermatophagoides pteronyssinus extracts after acidic treatmentEnrique Fernandez-Caldas
Research and Development, Laboratories LETI, Madrid, Spain
Int Arch Allergy Immunol 145:298-304. 2008....
Molecular and biochemical properties of storage mites (except Blomia species)Enrique Fernandez-Caldas
Research and Development Department, Laboratorios LETI, S L, Tres Cantos, Madrid, Spain
Protein Pept Lett 14:954-9. 2007..Herein we present a comprehensive review of the allergenicity of mite species which have been implicated in human respiratory and/or dermatological diseases...
Modulation of the humoral response to Dermatophagoides pteronyssinus allergens in BALB/c mice by extract modification and adjuvant useYago Pico de Coaña
Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Madrid, Spain
Int Arch Allergy Immunol 157:331-8. 2012..The objectives of this study were to investigate the humoral response generated in mice to modified Dermatophagoides pteronyssinus extracts in the presence or absence of two different adjuvants...
In vivo and in vitro allergenicity of the domestic mite Chortoglyphus arcuatusManuel Boquete
Allergy Department, Hospital Xeral de Calde, Lugo, Spain
Ann Allergy Asthma Immunol 97:203-8. 2006..arcuatus in northern Spain. Sensitization to this species should be considered of clinical significance. There is minimal cross-reactivity between C. arcuatus and D. pteronyssinus...
Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonicaYago Pico de Coaña
Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Madrid, Spain
Biochem Biophys Res Commun 401:451-7. 2010..Cup a 4 is expressed in mature pollen grains and shares antigenic properties with the recombinant form. Sera from 9.6% C. arizonica allergic patients contain specific IgE antibodies against recombinant Cup a 4...
