Research Topics
| Domingo A Pascual-FigalSummaryAffiliation: Hospital Universitario Virgen de la Arrixaca Country: Spain Publications
| Collaborators
|
Detail Information
Publications
Pulmonary surfactant protein B in the peripheral circulation and functional impairment in patients with chronic heart failureDomingo A Pascual-Figal
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Departamento de Medicina Interna, Universidad de Murcia, Murcia, Spain
Rev Esp Cardiol 62:136-42. 2009..Surfactant protein B (SP-B) is a marker of damage to the alveolar-capillary barrier that could be useful for monitoring functional impairment in patients with chronic heart failure (HF)...- [Prognostic value of BNP and cardiopulmonary exercise testing in patients with systolic heart failure on beta-blocker therapy]Domingo A Pascual-Figal
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 61:260-8. 2008..The long-term prognostic value of the B-type natriuretic peptide (BNP) level and cardiopulmonary exercise testing in patients with heart failure (HF) who are receiving beta-blocker therapy is not well established... - Usefulness of clinical and NT-proBNP monitoring for prognostic guidance in destabilized heart failure outpatientsDomingo A Pascual-Figal
Department of Cardiology, University Hospital Virgen de la Arrixaca, Ctra Madrid Cartagena s n, 30120 Murcia, Spain
Eur Heart J 29:1011-8. 2008..To study the relative prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) monitoring in addition to clinical disease severity scores (CDSSs) in outpatients with destabilized heart failure (HF)... - Red blood cell distribution width predicts long-term outcome regardless of anaemia status in acute heart failure patientsDomingo A Pascual-Figal
Heart Failure Unit, Cardiology Department, Virgen de la Arrixaca Hospital, School of Medicine, University of Murcia, Murcia, Spain
Eur J Heart Fail 11:840-6. 2009..To study the long-term prognostic value of red blood cell distribution width (RDW) in patients hospitalized with acute heart failure (AHF) and to compare the value of this measurement with haemoglobin levels and anaemia status... - Soluble ST2 for predicting sudden cardiac death in patients with chronic heart failure and left ventricular systolic dysfunctionDomingo A Pascual-Figal
Cardiology Service, Virgen de la Arrixaca Hospital and Department of Medicine, University of Murcia, Murcia 30120, Spain
J Am Coll Cardiol 54:2174-9. 2009..We studied whether the measurement of the soluble form of ST2 (sST2), an interleukin-1 receptor family member, could identify heart failure (HF) patients at risk of sudden cardiac death (SCD)... - Relation of B-type natriuretic peptide levels before and after exercise and functional capacity in patients with idiopathic dilated cardiomyopathyDomingo A Pascual-Figal
Cardiology Department, Hospital Universitario Virgen de la Arrixaca, University of Murcia, Murcia, Spain
Am J Cardiol 99:1279-83. 2007..6 +/- 4.8 vs 36.5 +/- 7.7, p = 0.026) independent of other clinical parameters. In conclusion, BNP release during exercise could be a determinant of functional capacity in patients with chronic HF and IDC... - B-type natriuretic peptide release in the coronary effluent after acute transient ischaemia in humansDomingo A Pascual-Figal
Department of Cardiology, University Hospital Virgen de la Arrixaca, University of Murcia, Murcia, Spain
Heart 93:1077-80. 2007..The association between B-type natriuretic peptide (BNP) and coronary artery disease is not fully understood... - Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patientsDomingo A Pascual-Figal
Cardiology Department, University Hospital Virgen de la Arrixaca, University of Murcia, Spain
Eur J Heart Fail 9:518-24. 2007..Uric acid (UA) may be involved in chronic heart failure (HF) pathogenesis, entailing a worse outcome. The purpose of this study was to examine the role of hyperuricaemia as a prognostic marker after hospital discharge in acute HF patients... - Sex hormone-binding globulin: a new marker of disease severity and prognosis in men with chronic heart failureDomingo A Pascual-Figal
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Departamento de Medicina, Facultad de Medicina, Universidad de Murcia, El Palmar, 30120 Murcia, Espana
Rev Esp Cardiol 62:1381-7. 2009..Sex hormone-binding globulin (SHBG) is a key regulator of the actions of anabolic steroids. Chronic heart failure (HF) has been associated with anabolic steroid deficiency, but its relationship with SHBG is not known... - [Evolution of severe mitral regurgitation after optimization of pharmacological therapy in non-ischemic dilated cardiomyopathy]Domingo A Pascual Figal
Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 59:176-9. 2006..At 6 months, MR decreased by at least one grade in 13 (87%) patients (P =.001), as did the effective regurgitant orifice area (from 0.41 [0.05] mm2 to 0.20 [0.15] mm2; P... - Soluble ST2, high-sensitivity troponin T- and N-terminal pro-B-type natriuretic peptide: complementary role for risk stratification in acutely decompensated heart failureDomingo A Pascual-Figal
Cardiology Department, Virgen de la Arrixaca Hospital and School of Medicine, University of Murcia, Murcia, Spain
Eur J Heart Fail 13:718-25. 2011..To investigate the use of biomarkers providing independent information regarding physiology in acutely decompensated heart failure (ADHF) for assessment of risk... - Preoperative statin therapy and troponin T predict early complications of coronary artery surgeryDomingo A Pascual
Department of Cardiology, Hospital Universitario Arrixaca, Murcia, Spain
Ann Thorac Surg 81:78-83. 2006..We sought to examine the association between preoperative statin therapy, systemic inflammation, and myocardial ischemia with the occurrence of early cardiac complications after coronary artery bypass grafting surgery... - [Usefulness of NTproBNP in the emergency management of patients with severe dyspnea and an uncertain heart failure diagnosis]Domingo A Pascual Figal
Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 58:1155-61. 2005..The test's usefulness may be greatest in patients with severe dyspnea of uncertain origin. However, NTproBNP has not been evaluated specifically in this setting... - Comparison of late mortality in hospitalized patients >70 years of age with systolic heart failure receiving beta blockers versus those not receiving beta blockersDomingo A Pascual-Figal
Cardiology Department, University Hospital Virgen de la Arrixaca, University of Murcia, Spain
Am J Cardiol 102:1711-7. 2008..This benefit remains consistent after adjustment for potential confounders... - Anabolic status and functional impairment in men with mild chronic heart failureFrancisco J Pastor-Pérez
Heart Failure Unit, Cardiology Department, University Hospital Virgen de la Arrixaca, University of Murcia, Murcia, Spain
Am J Cardiol 108:862-6. 2011.... - Soluble ST2 Is a Marker for Acute Cardiac Allograft RejectionDomingo A Pascual-Figal
Cardiology Service, Virgen de la Arrixaca Hospital and Department of Medicine, University of Murcia, Murcia, Spain
Ann Thorac Surg 92:2118-24. 2011..Soluble ST2 (sST2), an interleukin (IL)-1 receptor family member, has a role in immunologic tolerance and has also emerged as a biomarker of cardiac stretch and remodeling. The sST2 role in heart transplantation is still unknown... - [Usefulness of high sensitivity troponin T assay in detecting acute allograft rejection after heart transplantation]Carmen Muñoz-Esparza
Unidad de Insuficiência Cardíaca y Trasplante Cardíaco, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Espana
Rev Esp Cardiol 64:1109-13. 2011..In this study, the usefulness of a new highly sensitive method for the measurement of troponin T is evaluated... - [Prognostic role of new biomarkers in off-pump coronary artery bypass surgery]José M Arribas-Leal
Servicio de Cirugia Cardiovascular, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 59:280-3. 2006..No significant differences were found with biomarkers of inflammation (P.05). The presence of a preoperative troponin-T level > 0.10 ng/dL is associated with a higher risk of cardiac death or AMI in patients undergoing OPCAB surgery... - [Troponin-T monitoring in outpatients with nonischemic heart failure]Domingo A Pascual-Figal
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 61:678-86. 2008..The usefulness of prolonged troponin-T (TnT) monitoring in outpatients with nonischemic heart failure (HF) is not clear. The aim of this study was to investigate the incidence, prognostic value and determinants of a raised TnT level... - [Influence of gender on the clinical characteristics and prognosis of patients hospitalized for heart failure]Belén Redondo Bermejo
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 60:1135-43. 2007..The natural history of heart failure (HF) may be different in women due to their clinical characteristics, treatment and prognosis being distinct. Our aim was to describe the differential characteristics of women hospitalized with HF... - ?-trace protein and cystatin C as predictors of long-term outcomes in patients with acute heart failureSergio Manzano-Fernández
Department of Cardiology, University Hospital Virgen de Arrixaca, Murcia, Spain
J Am Coll Cardiol 57:849-58. 2011..The purpose of this study was to evaluate the prognostic importance of novel markers of renal dysfunction among patients with acutely destabilized heart failure (ADHF)... - Short-term variability of heart rate turbulence in chronic heart failureSergio Manzano-Fernández
Cardiology Department, University Hospital Virgen de la Arrixaca, Murcia, Spain
J Card Fail 17:735-41. 2011..The objective of this study was to assess the short-term variability of HRT and to compare the diagnostic yield of 7-day (7DH) versus 24-hour (1DH) Holter monitoring for calculating HRT in a CHF population... - [Comparative prognostic value of plasma and urinary N-terminal pro-B-type natriuretic peptide in patients with acute destabilized heart failure]Sergio Manzano-Fernández
Departamento de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 64:365-72. 2011..The aims of this study were to compare the prognostic value of plasma versus urinary NT-proBNP concentration for the risk stratification of patients with ADHF... - Impact of kidney dysfunction on plasma and urinary N-terminal pro-B-type natriuretic peptide in patients with acute heart failureSergio Manzano-Fernández
Department of Cardiology, University Hospital Virgen de la Arrixaca, Murcia, Spain
Congest Heart Fail 16:214-20. 2010..368). In patients with AHF and concomitant kidney dysfunction, the increased circulating NT-proBNP may be mainly related to increased cardiac secretion and not decreased renal clearance... - Usefulness of serial monitoring of B-type natriuretic peptide for the detection of acute rejection after heart transplantationIris P Garrido
Department of Cardiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Am J Cardiol 103:1149-53. 2009..In conclusion, serial monitoring of BNP, evaluated as a percentage of change, may be a useful noninvasive tool in the clinical management of rejection... - Metformin protects against doxorubicin-induced cardiotoxicity: involvement of the adiponectin cardiac systemMari C Asensio-López
Heart Failure Unit, Cardiology Department, University Hospital Virgen de la Arrixaca, 30120 Murcia, Spain
Free Radic Biol Med 51:1861-71. 2011..Taken together, these results demonstrate that metformin protects cardiomyocytes from doxorubicin-induced damage and that the cardiac adiponectin system plays an important role in this protective action... - Comparison of detection of arrhythmias in patients with chronic heart failure secondary to non-ischemic versus ischemic cardiomyopathy by 1 versus 7-day holter monitoringFrancisco J Pastor-Pérez
Department of Cardiology, Virgen de la Arrixaca University Hospital, Murcia, Spain
Am J Cardiol 106:677-81. 2010..In conclusion, 7DH clearly improves the detection and allows a better characterization of ventricular arrhythmic episodes but seems to be less useful for supraventricular events... - QRS duration and early hemodynamic instability after coronary revascularization surgeryJosé M Arribas Leal
Servicio de Cirugia Cardiovascular, Hospital Universitario Virgen de la Arrixaca, Murcia, Espana
Rev Esp Cardiol 62:652-9. 2009..The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established... - [Addition of an angiotensin II receptor blocker to maximal dose of ACE inhibitors in heart failure]Domingo A Pascual Figal
, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 55:862-6. 2002..After maximum ACE inhibitor doses, the addition of losartan is safe and associated with an improvement in ventricular function and NYHA functional class, but with no change in neurohormonal status... - [Clinical determinants and prognostic value of hemoglobin in hospitalized patients with systolic heart failure]Belén Redondo Bermejo
Servicio de Cardiologia, Unidad de Insuficiencia Cardiaca, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 60:597-606. 2007..The aims of this study were to identify determinants of the hemoglobin level in a large group of hospitalized patients with systolic HF and to investigate the medium-term prognostic value of the hemoglobin level... - Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitroJesús Sánchez-Más
Unidad de Insuficiencia Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Facultad de Medicina, Universidad de Murcia, El Palmar, Murcia, Spain
Rev Esp Cardiol 63:779-87. 2010.... - [Epidemiology and new predictors of atrial fibrillation after coronary surgery]José M Arribas-Leal
Servicio de Cirugia Cardiovascular, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 60:841-7. 2007..Our aims were to study its epidemiology and to identify predictors in everyday clinical practice, while taking into account statin use, extracorporeal circulation, and new biomarkers of inflammation and ventricular stress... - [Chest pain in clinical practice: impact of routine troponin determination on clinical manifestations and care]Domingo A Pascual Figal
, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 56:43-8. 2003..5, and generates high costs in hospital admissions. The routine use of serial troponin determinations was associated with a reduction in hospital admissions due to unstable angina and non-ischemic chest pain, and costs... - [Chest pain: a diagnostic and prognostic challenge]Domingo A Pascual-Figal
Med Clin (Barc) 126:15-6. 2006