Research Topics
| Vicenc FalcoSummaryAffiliation: Hospital Universitari Vall d'Hebron Country: Spain Publications
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Detail Information
Publications
Lactic acidosis related to nucleoside therapy in HIV-infected patientsVicenc Falco
Infectious Diseases Division, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, P masculine Vall d Hebron 119 129 08035, Barcelona, Spain
Expert Opin Pharmacother 4:1321-9. 2003..Therapy is based on supportive measures and discontinuation of all antiretroviral drugs. Administration of essential vitamin coenzymes, electron acceptors and L-carnitine may be useful in some cases...
Serological response to pneumococcal vaccination in HAART-treated HIV-infected patients: one year follow-up studyVicenc Falco
Infectious Disease Department, Hospital Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Vaccine 24:2567-74. 2006..In conclusion, the immunogenicity conferred by the polysaccharide vaccine in HIV-infected patients under HAART is at least as good as that observed in healthy subjects...
Influence of HAART on the clinical course of HIV-1-infected patients with progressive multifocal leukoencephalopathy: results of an observational multicenter studyVicenc Falco
Infectious Disease Department, Hospital Universitario Vall d Hebron, Barcelona, Spain
J Acquir Immune Defic Syndr 49:26-31. 2008....
[Treatment for Legionnaires' disease. Macrolides or quinolones?]Vicenc Falco
Servicios de Enfermedades Infecciosas, Hospital Universitario Vall d Hebron, Universidad Autonoma de Barcelona, Espana
Enferm Infecc Microbiol Clin 24:360-4. 2006..Macrolides and fluoroquinolones are the recommended treatment for Legionnaires' disease. The aim of our study was to analyze the clinical efficacy of clarithromycin, azithromycin and levofloxacin in patients with Legionnaires' disease...
Emerging drugs for pneumococcal pneumoniaVicenc Falco
Infectious Diseases Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Expert Opin Emerg Drugs 16:459-77. 2011..Fluorquinolones constitute an excellent alternative therapy. Patients with shock or severe sepsis should probably receive combination therapy with ?-lactams plus a macrolide due to its immunomodulatory effect...
Influence of penicillin resistance on outcome in adult patients with invasive pneumococcal pneumonia: is penicillin useful against intermediately resistant strains?Vicenc Falco
Infectious Disease Department, Hospitals Vall d Hebron, Universitat Autonoma de Barcelona, P degrees Vall d Hebron 119 129, 08035 Barcelona, Spain
J Antimicrob Chemother 54:481-8. 2004..12-1 mg/L treated empirically during the first 48 h with beta-lactam antibiotics...
Early monitoring of ribavirin serum concentration is not useful to optimize hepatitis C virus treatment in HIV-coinfected patientsManuel Crespo
Infectious Diseases Department, Hospital Universitari Vail d Hebron, Universitat Autonoma de Barcelona, Spain
Antivir Ther 12:1217-23. 2007..Therefore, it has been suggested that monitoring RBV serum levels could be used to drive dose modification and to optimize management of HCV-infected patients receiving combination treatment...
Response-guided therapy for chronic hepatitis C virus infection in patients coinfected with HIV: a pilot trialEva Van den Eynde
Infectious Diseases Department, Vall d Hebron Hospital, Autonomous University of Barcelona, Spain
Clin Infect Dis 48:1152-9. 2009..To study the feasibility of a response-guided therapy for chronic hepatitis C virus (HCV) infection in patients coinfected with human immunodeficiency virus (HIV) in a tertiary care hospital...
Once-daily regimen of saquinavir, ritonavir, didanosine, and lamivudine in HIV-infected patients with standard tuberculosis therapy (TBQD Study)Esteban Ribera
Infectious Diseases Service, Hospital Universitari Vall d Hebron, Barcelona, Spain
J Acquir Immune Defic Syndr 40:317-23. 2005....
Pharmacokinetic interaction between rifampicin and the once-daily combination of saquinavir and low-dose ritonavir in HIV-infected patients with tuberculosisEsteban Ribera
Infectious Diseases Department, Hospital Universitari Vall d Hebron, Barcelona, Spain
J Antimicrob Chemother 59:690-7. 2007..To assess plasma steady-state pharmacokinetics (PK) of rifampicin, isoniazid, saquinavir and ritonavir in HIV and tuberculosis (TB) co-infected patients, and investigate potential interactions between TB drugs and protease inhibitors (PIs)...
Improvements in subcutaneous fat, lipid profile, and parameters of mitochondrial toxicity in patients with peripheral lipoatrophy when stavudine is switched to tenofovir (LIPOTEST study)Esteban Ribera
Department of Infectious Diseases, Hospital Universitari Vall d Hebron, Barcelona, Spain
HIV Clin Trials 9:407-17. 2008..Lipoatrophy is the most stigmatizing side effect of stavudine therapy. We assessed the long-term effects of replacing stavudine with tenofovir in HIV-infected patients with lipoatrophy...
Raltegravir, etravirine, and ritonavir-boosted darunavir: a safe and successful rescue regimen for multidrug-resistant HIV-1 infectionArkaitz Imaz
Infectious Diseases Department, Hospital Universitari Vall d Hebron and Departament de Medicina, Universidad Autonoma de Barcelona, Barcelona, Spain
J Acquir Immune Defic Syndr 52:382-6. 2009..No data from clinical trials, about this combination, are available...
Invasive pneumococcal disease in HIV-infected adults: clinical changes after the introduction of the pneumococcal conjugate vaccine in childrenJoaquin Burgos
Department of Infectious Diseases, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
J Acquir Immune Defic Syndr 59:31-8. 2012..We conducted a multicenter study to analyze differences in clinical presentation of IPD between HIV-infected and non-HIV-infected adults in the prevaccine and postvaccine era...
Utility of week-4 viral response to tailor treatment duration in hepatitis C virus genotype 3/HIV co-infected patientsManuel Crespo
Infectious Diseases Department, Spain
AIDS 21:477-81. 2007..To investigate the utility of a week-4 virological response for sustained response prediction in hepatitis C virus (HCV) genotype 3/HIV-co-infected patients treated with interferon and ribavirin for 24 weeks...
The spectrum of pneumococcal empyema in adults in the early 21st centuryJoaquin Burgos
Infectious Diseases Department, Universitat Autonoma de Barcelona, Barcelona, Spain
Clin Infect Dis 53:254-61. 2011..Our objective was to describe the risk factors for pneumococcal empyema in adults and to analyze the differences in the incidence, disease characteristics, and serotype distribution between the pre- and post-PCV7 eras...
Efficacy of recombinant interleukin-2 (rIL-2) in patients with advanced HIV-1 infection and blunted immune response to HAARTManuel Crespo
Infectious Diseases Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Enferm Infecc Microbiol Clin 26:27-31. 2008..The primary endpoint was median change in CD4+ T-cell counts at the end of treatment as compared to baseline. Secondary endpoints were safety and changes in the various T-cell subpopulations...
Efficacy and safety of nucleoside reverse transcriptase inhibitor-sparing salvage therapy for multidrug-resistant HIV-1 infection based on new-class and new-generation antiretroviralsArkaitz Imaz
Infectious Diseases Department, Hospital Universitari Vall d Hebron, Barcelona, Spain
J Antimicrob Chemother 66:358-62. 2011..The advent of new antiretrovirals has expanded the therapeutic options for multiple drug-resistant HIV-1 infection. The role of recycled nucleoside reverse transcriptase inhibitors (NRTIs) in this scenario remains uncertain...
Abacavir coadministration does not interfere with the suppressive activity of ribavirin in an HCV replicon systemEva Van den Eynde
Infectious Diseases Department, Vall d Hebron Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
Antivir Ther 16:887-93. 2011..Here, we studied the effect of abacavir, tenofovir or lamivudine addition on the suppressive activity of ribavirin in an HCV RNA replicon system...
Leishmania infantum DNA detection in urine from patients with visceral leishmaniasis and after treatment controlRoser Fisa
Laboratory of Parasitology, Universitat de Barcelona, Barcelona, Spain
Am J Trop Med Hyg 78:741-4. 2008..This study suggests that urine-PCR is sensitive for diagnosis and may be useful to monitor treatment efficacy...
Spontaneous pyogenic vertebral osteomyelitis and endocarditis: incidence, risk factors, and outcomeCarlos Pigrau
Infectious Diseases Division, Hospital Universitari Vall d Hebron, Universitat Autonoma, Barcelona, Spain
Am J Med 118:1287. 2005..This study investigates the incidence and risk factors of infectious endocarditis in patients with pyogenic vertebral osteomyelitis, and the outcome of pyogenic vertebral osteomyelitis with and without associated infectious endocarditis...
Efficacy and safety of once-daily combination therapy with didanosine, lamivudine and nevirapine in antiretroviral-naive HIV-infected patientsEsteban Ribera
Infectious Diseases Service, Hospital Universitari Vall d Hebron, Barcelona, Spain
Antivir Ther 10:605-14. 2005..The purpose of this study was to evaluate the efficacy and safety of a once-daily regimen consisting of didanosine (ddI), lamivudine (3TC) and nevirapine (NVP) for adult antiretroviral-naive patients with HIV-1 infection...
Effectiveness of polysaccharide pneumococcal vaccine in HIV-infected patients: a case-control studyMaria Penaranda
Hospital Son Dureta, Barcelona, Spain
Clin Infect Dis 45:e82-7. 2007..Our objective was to determine the effectiveness of 23-valent PPV in HIV-infected adults and the risk factors for pneumococcal pneumonia or invasive pneumococcal disease...
Brief communication: treatment of Enterococcus faecalis endocarditis with ampicillin plus ceftriaxoneJoan Gavalda
Hospital Universitari Vall d Hebron, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
Ann Intern Med 146:574-9. 2007..High-level aminoglycoside resistance (HLAR) that precludes bactericidal synergism with penicillins or glycopeptides and nephrotoxicity related to aminoglycoside treatment are major problems in treating Enterococcus faecalis endocarditis...
Restoration of T cell responses to toxoplasma gondii after successful combined antiretroviral therapy in patients with AIDS with previous toxoplasmic encephalitisMarylène Lejeune
Immunology Service, Hospital Clinic Institut d Investigacions Biomèdiques Augustí Pi i Suñer, University of Barcelona, Barcelona, Spain
Clin Infect Dis 52:662-70. 2011..It is unknown whether a Toxoplasma gondii-specific T cell response is restored after successful combined antiretroviral therapy (cART) in patients with AIDS and current or previous toxoplasmic encephalitis (TE)...
Tuberculous trochanteric bursitis: report of 5 cases and literature reviewManuel Crespo
Hospital Universitari Vall d'Hebron, Universitat Autonoma, Barcelona, Spain
Scand J Infect Dis 36:552-8. 2004..This report presents 5 new cases of TTB and a review of the literature (1981-2003), with emphasis on clinical and radiological findings and treatment, in order to investigate the optimum therapeutic approach...
Value of culture and nested polymerase chain reaction of blood in the prediction of relapses in patients co-infected with leishmania and human immunodeficiency virusCristina Riera
Laboratori de Parasitologia, Facultat de Farmacia, Universitat de Barcelona, Barcelona, Spain
Am J Trop Med Hyg 73:1012-5. 2005..However, the presence of viable parasites during post-treatment follow-up increased the probability of relapse and showed that culture positivity could be a good relapse marker...
Antiretroviral salvage therapy for multiclass drug-resistant HIV-1-infected patients: from clinical trials to daily clinical practiceArkaitz Imaz
HIV Unit, Infectious Diseases Department, Hospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, Spain
AIDS Rev 13:180-93. 2011....
Current and potential usefulness of pneumococcal urinary antigen detection in hospitalized patients with community-acquired pneumonia to guide antimicrobial therapyRoger Sordé
Department of Infectious Diseases, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Arch Intern Med 171:166-72. 2011..We assessed the usefulness of pneumococcal urinary antigen detection in the diagnosis and antimicrobial guidance in patients hospitalized with CAP...
Steady-state pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adultsEsteban Ribera
Servicio de Enfermedades Infecciosas, Hospital Universitari Vall d Hebron, Paseo Vall Hebron 119 129, 08035 Barcelona, Spain
Antimicrob Agents Chemother 48:4256-62. 2004....
