Research Topics
| Jaime Huerta-CepasSummaryAffiliation: Center for Genomic Regulation Country: Spain Publications
| Collaborators
|
Detail Information
Publications
ETE: a python Environment for Tree ExplorationJaime Huerta-Cepas
Comparative Genomics Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Barcelona, Spain
BMC Bioinformatics 11:24. 2010..Currently, many genome-wide analyses rely on tree-like data representation and hence there is a growing need for scalable tools to handle tree structures at large scale...
MetaPhOrs: orthology and paralogy predictions from multiple phylogenetic evidence using a consistency-based confidence scoreLeszek P Pryszcz
Bioinformatics and Genomics Programme, Centre de Regulacio Genomica CRG, Universitat Pompeu Fabra, Dr Aiguader, 88 08003, Barcelona, Spain
Nucleic Acids Res 39:e32. 2011..A webserver has been developed to easily access these data (http://orthology.phylomedb.org), which provides users with a global repository of phylogeny-based orthology and paralogy predictions...
Evidence for short-time divergence and long-time conservation of tissue-specific expression after gene duplicationJaime Huerta-Cepas
Centre for Genomic Regulation, Barcelona, Spain
Brief Bioinform 12:442-8. 2011..Our results show that gene duplication leads to increased levels of tissue specificity and that this tends to occur promptly after the duplication event...
Assigning duplication events to relative temporal scales in genome-wide studiesJaime Huerta-Cepas
Centre for Genomic Regulation CRG, Barcelona, Spain
Bioinformatics 27:38-45. 2011....
PhylomeDB v3.0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralogy predictionsJaime Huerta-Cepas
Bioinformatics and Genomics Programme, Centre de Regulacio Genomica, 08003 Barcelona, Spain
Nucleic Acids Res 39:D556-60. 2011..Finally, PhylomeDB is currently being used by several genome sequencing projects that couple the genome annotation process with the reconstruction of the corresponding phylome, a strategy that provides relevant evolutionary insights...
PeroxisomeDB: a database for the peroxisomal proteome, functional genomics and diseaseAgatha Schluter
Centre de Genètica Mèdica i Molecular, Institut d Investigació Biomèdica de Bellvitge Institut de Recerca Oncològica IDIBELL IRO Hospital Duran i Reynals, Granvia km 2, 7 08907 Hospitalet de Llobregat, Barcelona, Spain
Nucleic Acids Res 35:D815-22. 2007..PeroxisomeDB should contribute to the systematic characterization of the peroxisomal proteome and facilitate system biology approaches on the organelle...
Evidence for systems-level molecular mechanisms of tumorigenesisPilar Hernandez
Bioinformatics and Biostatistics Unit, and Translational Research Laboratory, Catalan Institute of Oncology, IDIBELL, L Hospitalet, Barcelona, Spain
BMC Genomics 8:185. 2007..Coordinated reprogramming would allow the cell to acquire the capabilities for malignant growth...
