Research Topics
Species | Toni GabaldónSummaryAffiliation: Center for Genomic Regulation Country: Spain Publications
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Detail Information
Publications
Immunity and other defenses in pea aphids, Acyrthosiphon pisumNicole M Gerardo
Department of Biology, Emory University, O Wayne Rollins Research Center, 1510 E, Clifton Road NE, Atlanta, GA 30322, USA
Genome Biol 11:R21. 2010....
Phylogenomics of the oxidative phosphorylation in fungi reveals extensive gene duplication followed by functional divergenceMarina Marcet-Houben
Comparative Genomics, Centre for Genomics Regulation, 08003 Barcelona, Spain
BMC Evol Biol 9:295. 2009..To identify the main mechanisms behind the evolution of respiratory pathways, we conducted a phylogenomics survey of oxidative phosphorylation components in the genomes of sixty fungal species...
Evolution of spliceosomal introns following endosymbiotic gene transferNahal Ahmadinejad
Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
BMC Evol Biol 10:57. 2010..We circumvent this problem by using genes originated by endosymbiotic gene transfer, in which an intron-less structure at the time of the transfer can be assumed...
Peroxisome diversity and evolutionToni Gabaldón
Centre for Genomic Regulation CRG, Dr Aiguader, 88 08003 Barcelona, Spain
Philos Trans R Soc Lond B Biol Sci 365:765-73. 2010..Here, I review recent advances in our understanding of peroxisome diversity and evolution, with a special emphasis on peroxisomes in microbial eukaryotes...
Large-scale assignment of orthology: back to phylogenetics?Toni Gabaldón
Bioinformatics and Genomics Program, Center for Genomic Regulation, Doctor Aiguader 88, Barcelona, Spain
Genome Biol 9:235. 2008..Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies...
PeroxisomeDB 2.0: an integrative view of the global peroxisomal metabolomeAgatha Schluter
Neurometabolic Disease Lab, Institut de Neuropatologia de Bellvitge, Gran Via n 199, 08907 L Hospitalet de Llobregat, Barcelona, Spain
Nucleic Acids Res 38:D800-5. 2010..0 is a freely available, highly interactive functional genomics platform that offers an extensive view on the peroxisomal metabolome across lineages, thus facilitating comparative genomics and systems analysis of the organelle...
ETE: a python Environment for Tree ExplorationJaime Huerta-Cepas
Comparative Genomics Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Barcelona, Spain
BMC Bioinformatics 11:24. 2010..Currently, many genome-wide analyses rely on tree-like data representation and hence there is a growing need for scalable tools to handle tree structures at large scale...
TreeKO: a duplication-aware algorithm for the comparison of phylogenetic treesMarina Marcet-Houben
Centre for Genomic Regulation, UPF, Doctor Aiguader 88, 08003 Barcelona, Spain
Nucleic Acids Res 39:e66. 2011..In addition treeKO, implements the possibility of computing phylome support values, and reconciliation-based measures such as the number of inferred duplication and loss events...
MetaPhOrs: orthology and paralogy predictions from multiple phylogenetic evidence using a consistency-based confidence scoreLeszek P Pryszcz
Bioinformatics and Genomics Programme, Centre de Regulacio Genomica CRG, Universitat Pompeu Fabra, Dr Aiguader, 88 08003, Barcelona, Spain
Nucleic Acids Res 39:e32. 2011..A webserver has been developed to easily access these data (http://orthology.phylomedb.org), which provides users with a global repository of phylogeny-based orthology and paralogy predictions...
Evidence for short-time divergence and long-time conservation of tissue-specific expression after gene duplicationJaime Huerta-Cepas
Centre for Genomic Regulation, Barcelona, Spain
Brief Bioinform 12:442-8. 2011..Our results show that gene duplication leads to increased levels of tissue specificity and that this tends to occur promptly after the duplication event...
Assigning duplication events to relative temporal scales in genome-wide studiesJaime Huerta-Cepas
Centre for Genomic Regulation CRG, Barcelona, Spain
Bioinformatics 27:38-45. 2011....
trimAl: a tool for automated alignment trimming in large-scale phylogenetic analysesSalvador Capella-Gutierrez
Comparative Genomics Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation, 88 08003 Barcelona, Spain
Bioinformatics 25:1972-3. 2009..cgenomics.org) and can be used online through the Phylemon web server (http://phylemon2.bioinfo.cipf.es/). Supplementary Material is available at http://trimal.cgenomics.org/publications...
TACC3-TSC2 maintains nuclear envelope structure and controls cell divisionLaia Gómez-Baldó
Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Barcelona, Spain
Cell Cycle 9:1143-55. 2010....
A midzone-based ruler adjusts chromosome compaction to anaphase spindle lengthGabriel Neurohr
Centre for Genomic Regulation CRG, Barcelona, Spain
Science 332:465-8. 2011..Thus, the anaphase spindle may function as a ruler to adapt the condensation of chromatids, promoting their segregation regardless of chromosome or spindle length...
PeroxisomeDB: a database for the peroxisomal proteome, functional genomics and diseaseAgatha Schluter
Centre de Genètica Mèdica i Molecular, Institut d Investigació Biomèdica de Bellvitge Institut de Recerca Oncològica IDIBELL IRO Hospital Duran i Reynals, Granvia km 2, 7 08907 Hospitalet de Llobregat, Barcelona, Spain
Nucleic Acids Res 35:D815-22. 2007..PeroxisomeDB should contribute to the systematic characterization of the peroxisomal proteome and facilitate system biology approaches on the organelle...
Acquisition of prokaryotic genes by fungal genomesMarina Marcet-Houben
Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Doctor Aiguader, 88 08003 Barcelona, Spain
Trends Genet 26:5-8. 2010..Transferred genes included bacterial arsenite reductase, catalase, different racemases and peptidoglycan metabolism enzymes. Our results suggest an important role for HGT in fungal evolution...
Eukaryotic cold shock domain proteins: highly versatile regulators of gene expressionMarija Mihailovich
Gene Regulation Programme, Centre de Regulació Genòmica CRG UPF, Barcelona, Spain
Bioessays 32:109-18. 2010..This review summarizes the current knowledge on eukaryotic CSD/S1 domain-containing proteins with a special emphasis on UNR (upstream of N-ras), a member of this family with multiple copies of the CSD...
