Research Topics
| Loreto CarmonaSummaryCountry: Spain Publications
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Publications
Increased risk of tuberculosis in patients with rheumatoid arthritisLoreto Carmona
Hospital Clinico San Carlos, Madrid, Spain
J Rheumatol 30:1436-9. 2003..To quantify the risk of tuberculosis (TB) in an unselected sample of patients with rheumatoid arthritis (RA) compared to the risk in the general population...
Longitudinal power Doppler ultrasonographic assessment of joint inflammatory activity in early rheumatoid arthritis: predictive value in disease activity and radiologic progressionEsperanza Naredo
Hospital Severo Ochoa, Madrid, Spain
Arthritis Rheum 57:116-24. 2007....
Clinical composite measures of disease activity for diagnosis and followup of undifferentiated peripheral inflammatory arthritis: a systematic reviewIsabel Castrejón
Hospital La Princesa, C Diego de Leon 62, Madrid, Spain
J Rheumatol Suppl 87:48-53. 2011..To critically appraise the validity of activity indices used in the followup of patients with undifferentiated peripheral inflammatory arthritis (UPIA)...
Switching TNF antagonists in patients with chronic arthritis: an observational study of 488 patients over a four-year periodJuan J Gomez-Reino
Rheumatology Service and Department of Medicine, Hospital Clinico Universitario, Medical School, Universidad de Santiago de Compostela, Spain
Arthritis Res Ther 8:R29. 2006..This issue will deserve continuous reassessment with the arrival of new medications...
Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis. Data from the Spanish registry BIOBADASERLoreto Carmona
Research Unit, Spanish Society of Rheumatology, Madrid, Spain Marques de Duero 5, 28001 Madrid, Spain
Arthritis Res Ther 8:R72. 2006..Because chronic therapy is necessary, continual review of this issue is necessary...
How good is to switch between biologics? A systematic review of the literatureLoreto Carmona
Unidad de Investigacion, Fundación Española de Reumatología, Madrid, Spain
Acta Reumatol Port 32:113-28. 2007..Perhaps the best alternative when a first TNF-antagonist fails is to start a different type of biologic, and leave the switch to another TNF-antagonist in the case of adverse event to the previous one...
Rheumatoid arthritis in Spain: occurrence of extra-articular manifestations and estimates of disease severityL Carmona
Rheumatology Department, H Clinico San Carlos, Madrid, Spain
Ann Rheum Dis 62:897-900. 2003..To characterise RA in a sample of Spanish patients by estimating mean clinical activity, functional ability, and radiological damage, and current and cumulative prevalence of extra-articular manifestations...
The burden of musculoskeletal diseases in the general population of Spain: results from a national surveyL Carmona
Research Unit, Hospital Universitario de la Princesa, Madrid, Spain
Ann Rheum Dis 60:1040-5. 2001....
Cancer in patients with rheumatic diseases exposed to TNF antagonistsLoreto Carmona
Research Unit, Sociedad Española de Reumatología, Madrid, Spain
Semin Arthritis Rheum 41:71-80. 2011..To describe the risk of cancer in patients exposed to tumor necrosis factor (TNF) antagonists...
Musculoskeletal work disability for clinicians: time course and effectiveness of a specialized intervention program by diagnosisLydia Abasolo
Hospital Clinico San Carlos, Madrid, Spain
Arthritis Rheum 57:335-42. 2007..To evaluate how an intervention program modifies the clinical course of work disability in musculoskeletal diagnoses...
Power Doppler ultrasonographic monitoring of response to anti-tumor necrosis factor therapy in patients with rheumatoid arthritisEsperanza Naredo
Hospital Severo Ochoa, Madrid, Spain
Arthritis Rheum 58:2248-56. 2008..To evaluate the validity, responsiveness, and predictive value of power Doppler ultrasonography (PDUS) monitoring of response to tumor necrosis factor (TNF) blocking agents in rheumatoid arthritis (RA)...
Prevalence and impact of fibromyalgia on function and quality of life in individuals from the general population: results from a nationwide study in SpainA J Mas
Rheumatology Department, Hospital Son Llatzer, Palma de Mallorca, Spain
Clin Exp Rheumatol 26:519-26. 2008..To estimate the prevalence of fibromyalgia (FM) and to compare some descriptive epidemiological and quality of life data between persons with and without FM criteria in a representative sample of the general Spanish population...
Prognostic factors in short-term disability due to musculoskeletal disordersLydia Abasolo
Hospital Clinico San Carlos, Madrid, Spain
Arthritis Rheum 59:489-96. 2008..To identify factors associated with poor outcome in temporary work disability (TWD) due to musculoskeletal disorders (MSDs)...
Cancer in rheumatoid arthritis: occurrence, mortality, and associated factors in a South European populationLydia Abasolo
Rheumatology Department, Hospital Clinico San Carlos, Madrid, Spain
Semin Arthritis Rheum 37:388-97. 2008..To estimate the prevalence, incidence, mortality, and predictors of cancer in patients with rheumatoid arthritis (RA)...
Burden of disease across chronic diseases: a health survey that measured prevalence, function, and quality of lifeEstibaliz Loza
Rheumatology Unit, Hospital Clinico San Carlos, and the Research Unit, Spanish Foundation of Rheumatology, Madrid, Spain
J Rheumatol 35:159-65. 2008..To assess health related quality of life (HRQOL) and functional ability across groups of chronic diseases in Spain...
Patterns of disease modifying antirheumatic drug use in a Spanish cohort of patients with rheumatoid arthritisIsidoro Gonzalez-Alvaro
Department of Rheumatology, Hospital Universitario de la Princesa, Madrid, Spain
J Rheumatol 30:697-704. 2003..To determine the adequacy of disease modifying antirheumatic drug (DMARD) prescription to disease activity in patients with rheumatoid arthritis (RA) and to assess whether the reasons for DMARD discontinuation agree with published evidence...
Value of Disease Activity Score 28 (DAS28) and DAS28-3 compared to American College of Rheumatology-defined remission in rheumatoid arthritisAlejandro Balsa
Rheumatology Unit, Hospital Universitario La Paz, Madrid, Spain
J Rheumatol 31:40-6. 2004....
Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohortIsidoro Gonzalez-Alvaro
Rheumatology Service, Hospital Universitario de la Princesa, Madrid, Spain
Arthritis Res Ther 10:R138. 2008..In the present work we estimate the effect of these factors on disease activity and function in patients with rheumatoid arthritis at the beginning of the new century...
Multimorbidity: prevalence, effect on quality of life and daily functioning, and variation of this effect when one condition is a rheumatic diseaseEstibaliz Loza
Rheumatology Unit, Hospital Clinico San Carlos, Madrid, Spain
Semin Arthritis Rheum 38:312-9. 2009....
Safety and retention rate of off-label uses of TNF antagonists in rheumatic conditions: data from the Spanish registry BIOBADASER 2.0Loreto Carmona
Research Unit, Spanish Society of Rheumatology, Madrid, Spain
Rheumatology (Oxford) 50:85-92. 2011..To compare the safety and retention rate of TNF antagonists used in approved indications (AIs) and non-AIs...
All-cause and cause-specific mortality in rheumatoid arthritis are not greater than expected when treated with tumour necrosis factor antagonistsLoreto Carmona
Research Unit, Spanish Foundation of Rheumatology, Madrid, Spain
Ann Rheum Dis 66:880-5. 2007..Mortality is increased in rheumatoid arthritis (RA), mainly because of cardiovascular (CV) events, cancer and infections. Recent data suggest that treatment with tumour necrosis factor (TNF) antagonists may affect this trend...
Demyelinating disease in patients treated with TNF antagonists in rheumatology: data from BIOBADASER, a pharmacovigilance database, and a systematic reviewMaría Cruz Fernández-Espartero
Rheumatology Department, Hospital Universitario de Móstoles, Mostoles, Spain
Semin Arthritis Rheum 40:330-7. 2011..To estimate the rate of demyelinating diseases in patients with rheumatic diseases treated with tumor necrosis factor (TNF) antagonists and to describe the cases reported to 3 different pharmacovigilance sources...
Economic burden of knee and hip osteoarthritis in SpainEstibaliz Loza
Hospital Clinico San Carlos, Madrid, Spain
Arthritis Rheum 61:158-65. 2009..To estimate the direct and indirect osteoarthritis (OA)-attributable costs and predictors of costs of knee and hip OA in Spain...
Change in the discontinuation pattern of tumour necrosis factor antagonists in rheumatoid arthritis over 10 years: data from the Spanish registry BIOBADASER 2.0Juan J Gomez-Reino
Rheumatology Department, Hospital Clinico Universitario, Santiago de Compostela, Spain
Ann Rheum Dis 71:382-5. 2012..To investigate in rheumatoid arthritis (RA) the rate and reason of discontinuation of tumour necrosis factor (TNF) antagonists over the past decade...
Effectiveness of recommendations to prevent reactivation of latent tuberculosis infection in patients treated with tumor necrosis factor antagonistsLoreto Carmona
Spanish Society of Rheumatology, Madrid, Spain
Arthritis Rheum 52:1766-72. 2005..CONCLUSION: Strategies to treat latent TB infection that are tailored to the at-risk population can effectively and safely lessen the likelihood of active TB in patients treated with TNF antagonists...
Survival, causes of death, and risk factors associated with mortality in Spanish systemic sclerosis patients: results from a single university hospitalBeatriz E Joven
Hospital Universitario 12 de Octubre, Servicio de Reumatologia, Madrid, Spain
Semin Arthritis Rheum 39:285-93. 2010..To analyze the causes of death, survival, and risk factors for mortality in a large series of Spanish systemic sclerosis (SSc) patients followed over the last 25 years in a tertiary care university hospital...
Demyelinating disease in patients treated with TNF antagonists in rheumatology: data from BIOBADASER, a pharmacovigilance database, and a systematic reviewMaría Cruz Fernández-Espartero
Rheumatology Department, Hospital Universitario de Móstoles, Mostoles, Spain
Semin Arthritis Rheum 41:524-33. 2011..To estimate the rate of demyelinating diseases in patients with rheumatic diseases treated with tumor necrosis factor (TNF) antagonists and to describe the cases reported to 3 different pharmacovigilance sources...
The prevalence of rheumatoid arthritis in the general population of SpainL Carmona
Research Unit, Hospital de la Princesa, , 62, 28006 Madrid, Spain
Rheumatology (Oxford) 41:88-95. 2002..RA may be less frequent in rural settings, a finding that merits further research. A significant proportion of RA cases in the community remain undiagnosed despite impaired functional status...
Prevalence and associated factors of anterior atlantoaxial luxation in a nation-wide sample of rheumatoid arthritis patientsA Naranjo
Rheumatology Department, Hospital Dr Negrin, Las Palmas, Spain
Clin Exp Rheumatol 22:427-32. 2004..To estimate the prevalence of anterior atlantoaxial subluxation (AAS) in patients with rheumatoid arthritis (RA), and to analyse its association with disease markers...
A model for the development and implementation of a national plan for the optimal management of early spondyloarthritis: the Esperanza ProgramSantiago Muñoz-Fernández
Rheumatology Unit, Hospital Infanta Sofia, San Sebastian de los Reyes, Madrid, Spain
Ann Rheum Dis 70:827-30. 2011..To evaluate the performance of a healthcare programme in early spondyloarthritis (SpA)...
Disease pattern of spondyloarthropathies in Spain: description of the first national registry (REGISPONSER) extended reportE Collantes
Department of Rheumatology, Hospital Reina Sofia and University of Córdoba, Cordoba, Spain
Rheumatology (Oxford) 46:1309-15. 2007....
Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding)J A Martinez Lopez
Research Unit, Fundación Española de Reumatología, Madrid, Spain
Clin Exp Rheumatol 27:678-84. 2009..To analyze the safety of methotrexate (MTX) in rheumatoid arthritis (RA) regarding the reproductive system (fertility, pregnancy, and breastfeeding)...
Effectiveness of a clinical practice intervention in early rheumatoid arthritisMiguel Angel Descalzo
Sociedad Española de Reumatología, Madrid, Spain
Arthritis Care Res (Hoboken) 64:321-30. 2012..To compare the outcome of early rheumatoid arthritis (RA) patients in a country where early clinics were established versus the outcome of patients in nonprotocolized clinics...
An audit of the variability of diagnosis and management of gout in the rheumatology setting: the gout evaluation and management studyFernando Perez-Ruiz
Rheumatology Department, Hospital de Cruces, Baracaldo, Spain
J Clin Rheumatol 17:349-55. 2011....
Systematic review on the effectiveness of immunosuppressants and biological therapies in the treatment of autoimmune posterior uveitisEsperanza Pato
Rheumatology Department, Hospital Clinico San Carlos, Madrid, Spain
Semin Arthritis Rheum 40:314-23. 2011..To analyze the effectiveness of immunosuppressants and biological therapies in autoimmune posterior uveitis, chronic anterior uveitis associated with juvenile idiopathic arthritis, and macular edema...
Costs and predictors of costs in rheumatoid arthritis: a prevalence-based studyCristina Lajas
, Madrid, Spain
Arthritis Rheum 49:64-70. 2003..CONCLUSION: Our data show a remarkable economic impact of RA over society and link the costs of the disease to its consequences in terms of functional disability, work disability, and housework disability...
Rheumatoid arthritisLoreto Carmona
Research Unit, Spanish Society of Rheumatology, Calle Marqués del Duero, 5, 28001 Madrid, Spain
Best Pract Res Clin Rheumatol 24:733-45. 2010..Age, sex, smoking, shared epitope and others correlate with its RA. The most important determinants of prognosis in RA are the severity at presentation and the management of the disease, both of which are subject to inequalities...
Survival, mortality and causes of death in inflammatory myopathiesCarmen Torres
Hospital 12 de Octubre, , Madrid, Spain
Autoimmunity 39:205-15. 2006..Cancer and cardiac involvement are important causes of death, and also prognostic factors for mortality in our group of patients. A careful search for cardiac involvement should be done in every patient with IM...
[Systematic review: are major opioids effective in the treatment of musculoskeletal pain?]Lydia Abasolo
Servicio de Reumatologia, Hospital Clinico San Carlos, Madrid, Espana
Med Clin (Barc) 128:291-301. 2007..To evaluate the efficacy of major opioids in the treatment of musculoskeletal pain...
A systematic review on the optimum management of the use of methotrexate in rheumatoid arthritis patients in the perioperative period to minimize perioperative morbidity and maintain disease controlE Loza
Hospital Clinico San Carlos, Madrid, Spain
Clin Exp Rheumatol 27:856-62. 2009..To examine the use of metho-trexate (MTX) in rheumatoid arthritis (RA) patients during the perioperative period...
[Biobadaser 2.0: analysis and trends in 2009]Miguel Angel Descalzo
Unidad de Investigacion, Sociedad Española de Reumatología, Madrid, Espana
Reumatol Clin 6:240-3. 2010..To update the information on long-term safety of biological therapies used for the treatment of rheumatic diseases...
Diagnostic and prognostic value of genetics in undifferentiated peripheral inflammatory arthritis: a systematic reviewLucía Silva-Fernández
Servicio de Reumatologia, Hospital Universitario Puerta de Hierro Majadahonda, Joaquín Rodrigo 2, Majadahonda, Madrid, Spain
J Rheumatol Suppl 87:38-44. 2011..To evaluate the diagnostic and prognostic utility of genetic testing in undifferentiated peripheral inflammatory arthritis (UPIA)...
Ultrasonographic assessment of inflammatory activity in rheumatoid arthritis: comparison of extended versus reduced joint evaluationE Naredo
Department of Rheumatology and Research Unit, Hospital de la Princesa, Madrid, Spain
Clin Exp Rheumatol 23:881-4. 2005..To investigate the validity of reduced joint counts for ultrasonographic (US) assessment of joint inflammatory activity in patients with rheumatoid arthritis (RA)...
Are the C-reactive protein values and erythrocyte sedimentation rate equivalent when estimating the 28-joint disease activity score in rheumatoid arthritis?I Castrejon
Rheumatology Service, Hospital Universitario de la Princesa, Madrid, Spain
Clin Exp Rheumatol 26:769-75. 2008..A formula for calculating disease activity score with 28 joint counts (DAS28) with C-reactive protein (CRP) instead of the erythrocyte sedimentation rate (ESR) has been proposed...
Assessment of inflammatory activity in rheumatoid arthritis: a comparative study of clinical evaluation with grey scale and power Doppler ultrasonographyE Naredo
Department of Rhumatology, Hospital de la Princeca, Madrid, Spain
Ann Rheum Dis 64:375-81. 2005..To compare the clinical assessment of overall inflammatory activity in patients with rheumatoid arthritis (RA) with grey scale and power Doppler (PD) ultrasonography (US)...
Early spondyloarthritis: results from the pilot registry ESPIDEPS Munoz-Fernandez
Rheumatology Section, Hospital Infanta Sofia, Madrid, Spain
Clin Exp Rheumatol 28:498-503. 2010..Early SpA clinics should facilitate the detection of new cases as well as to decrease the diagnosis and treatment delay. However, the workload of such clinics has not been estimated...
Observed and expected frequency of comorbid chronic diseases in rheumatic patientsE Loza
Rheumatology Unit, Hospital Clinico San Carlos, Madrid, Spain
Ann Rheum Dis 67:418-21. 2008..To estimate and compare the observed and expected prevalence of the co-existence of rheumatic diseases (RD) with other chronic conditions...
Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance reportJuan J Gomez-Reino
Hospital Clinico Universitario and Universidad de Santiago de Compostela, Santiago, Spain
Arthritis Rheum 48:2122-7. 2003..We undertook this study to determine and describe the long-term safety of 2 of these agents, infliximab and etanercept, in rheumatic diseases based on a national active-surveillance system following the commercialization of the drugs...
Risk of tuberculosis in patients treated with tumor necrosis factor antagonists due to incomplete prevention of reactivation of latent infectionJuan J Gomez-Reino
Hospital Clinico Universitario, University of Santiago de Compostela School of Medicine, Santiago, Spain
Arthritis Rheum 57:756-61. 2007....
Assessing utility values in rheumatoid arthritis: a comparison between time trade-off and the EuroQolRafael Ariza-Ariza
Rheumatology Service, Hospital Universitario Virgen Macarena, Seville, Spain
Arthritis Rheum 55:751-6. 2006....
Origins of erosive arthritisAntonio Juan-Mas
J Rheumatol 32:1632; author reply 1632-3. 2005
Quantifying risks: the case between glucocorticoids and tuberculosisLoreto Carmona
Arthritis Rheum 55:1-2. 2006
