Research Topics
Species | Herbert AuerSummaryCountry: Spain Publications
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Publications
Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarraysHerbert Auer
Center for Childhood Cancer, Columbus Children s Research Institute and The Ohio State University, Columbus, Ohio, USA
BMC Genomics 8:111. 2007..Current aCGH methods have limited resolution, sensitivity and reproducibility. Microarrays for aCGH are available only for a few organisms and combination of aCGH data with expression data is cumbersome...
Transcriptional profiling of the megabladder mouse: a unique model of bladder dysmorphogenesisSunita Singh
Center for Cell and Developmental Biology, Columbus Children s Research Institute, Columbus, Ohio 43205, USA
Dev Dyn 237:170-86. 2008....
Expression Profiling Using Affymetrix GeneChip MicroarraysHerbert Auer
Columbus Children s Research Institute, Columbus, OH, USA
Methods Mol Biol 509:35-46. 2009....
Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasionVasily Vasko
Department of Medicine, Arthur G James Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 104:2803-8. 2007..We conclude that EMT is common in PTC invasion and that vimentin regulates thyroid cancer EMT in vitro...
Innate and adaptive immune activation in the brain of MPS IIIB mouse modelJulianne DiRosario
Center for Gene Therapy, Columbus, Ohio 43205, USA
J Neurosci Res 87:978-90. 2009..Our data indicate that immune responses contribute greatly to the neuropathology of MPS IIIB and should be considered as an adjunct treatment in future therapeutic developments for optimal therapeutic effect...
Disruption of ZAS3 in mice alters NF-kappaB and AP-1 DNA binding and T-cell developmentCarl E Allen
Department of Pediatrics and Center for Cell and Developmental Biology, Columbus Children s Research Institute, Columbus, OH 43205, USA
Gene Expr 14:83-100. 2007..In CD3+ ZAS3-/- thymocytes, the CD4/ CD8 ratio was decreased and CD69 expression was decreased. In peripheral CD4+ ZAS3-/- lymphocytes we observed an increased number of memory T cells...
20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcomeLaura T Smith
Division of Human Cancer Genetics, Department of Molecular Virology, Immunology and Medical Genetics, Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University, Columbus, OH, USA
Genes Chromosomes Cancer 45:957-66. 2006..001) was the only factor to reach statistical significance. 20q11.1 amplification can be used as a marker of prognostic importance in GCTb. We propose TPX2 as a candidate oncogene in the core-amplified region at 20q11.1...
Quantification of DNA methylation in electrofluidics chips (Bio-COBRA)Romulo M Brena
Department of Molecular Genetics, The Ohio State University, 420 West 12th Ave, Room 435, Columbus, Ohio 43210, USA
Nat Protoc 1:52-8. 2006..The Bio-COBRA assay can be performed on 12 samples in less than 1 h. If the protocol is started at the DNA isolation step, however, approximately 48 h would be required to complete the entire procedure...
MYC amplification and polysomy 8 in chondrosarcoma: array comparative genomic hybridization, fluorescent in situ hybridization, and association with outcomeCarl Morrison
Division of Orthopedic Oncology, Department of Pathology, Center for Biostatistics, The Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University Medical School, Columbus, OH, USA
J Clin Oncol 23:9369-76. 2005..To identify recurrent regions of genomic gain or loss in chondrosarcoma in a clinically relevant and statistically valid fashion. Materials and..
Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genesClaudia D Baldus
Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 101:3915-20. 2004..Our results highlight the value of molecularly dissecting leukemic cells with complex karyotypes...
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genesStefan Amatschek
Department of Dermatology, University of Vienna, Vienna, Austria
Cancer Res 64:844-56. 2004..The gene dendogram clearly separates two groups of genes, those up-regulated such as cyclin B1, TGF-beta 3, B-Myb, Erg2, VCAM-1, and CD44 and those down-regulated such as MIG-6, Esp15, and CAK in patients with short survival time...
The ABRF MARG microarray survey 2005: taking the pulse of the microarray fieldKevin L Knudtson
University of Iowa, DNA Facility, 323 EMRB, Iowa City, IA 52242, USA
J Biomol Tech 17:176-86. 2006..Presented herein are the results of the MARG 2005 survey; where possible, trends in the field are discussed and compared to data collected from previous surveys...
Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profilesHidewaki Nakagawa
Division of Human Cancer Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus 43210, USA
Oncogene 23:7366-77. 2004..The distinct molecular expression profiles of cancer-associated fibroblasts in colon cancer metastasis support the notion that these fibroblasts form a favorable microenvironment for cancer cells...
[Relevance of parasitological examinations for the clinical course, epidemiology and prevention of alveolar echinococcosis - experiences of more than two decades in Austria]Herbert Auer
Abteilung fur Medizinische Parasitologie, Klinisches Institut fur Hygiene und Medizinische Mikrobiologie, MUW, Wien, Austria
Wien Klin Wochenschr 118:18-26. 2006..In addition, molecular biological tools for the detection of E. multilocularis (as well as E. granulosus strain) specific DNA in surgical resected and bioptic materials complete our diagnostic spectrum of methods...
Big results from small samples: evaluation of amplification protocols for gene expression profilingAgnes Viale
Bionomics Research and Technology Center, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08857, USA
J Biomol Tech 18:150-61. 2007..PCR validation showed an interaction of probe sequence on the array and target labeling chemistry, resulting in a chemistry-dependent probe set sensitivity varying over an order of magnitude...
HOXB4's road map to stem cell expansionBernhard Schiedlmeier
Department of Experimental Hematology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Proc Natl Acad Sci U S A 104:16952-7. 2007..In summary, our results strongly suggest that HOXB4 modulates the response of HSCs to multiple extrinsic signals in a concerted manner, thereby shifting the balance toward stem cell self-renewal...
ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysisJorge Guzman
Departments of Anesthesiology, and Cardiothoracic Surgery, Ball State University, Muncie, Indiana, USA
Inflamm Bowel Dis 12:766-89. 2006..ADOA3R is new potential therapeutic target for inflammatory bowel disease...
Chipping away at the chip bias: RNA degradation in microarray analysisHerbert Auer
Nat Genet 35:292-3. 2003
