Research Topics
| H J ZarSummaryAffiliation: University of Cape Town Country: South Africa Publications
| Collaborators
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Detail Information
Publications
Home-made spacers for bronchodilator therapy in children with acute asthma: a randomised trialH J Zar
Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, South Africa
Lancet 354:979-82. 1999..We tested the efficacy of home-made spacers (500 mL plastic bottle, polystyrene cup) compared with a conventional spacer for delivery of a beta2 agonist via MDI for children with acute asthma...- A 500-ml plastic bottle: an effective spacer for children with asthmaHeather J Zar
Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
Pediatr Allergy Immunol 13:217-22. 2002..It is concluded that a modified 500-ml plastic bottle is an effective spacer; modification and use of this device should be incorporated into international guidelines for the management of children with asthma... - Nosocomial pneumonia in pediatric patients: practical problems and rational solutionsHeather J Zar
Department of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, 46 Sawkins Road, Cape Town, South Africa
Paediatr Drugs 4:73-83. 2002..Of these, hand hygiene, appropriate infection control policies, and judicious use of antibacterials are essential... - The impact of HIV infection and trimethoprim-sulphamethoxazole prophylaxis on bacterial isolates from children with community-acquired pneumonia in South AfricaHeather J Zar
School of Child and Adolescent Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
J Trop Pediatr 49:78-83. 2003..17 of 79 (22 per cent), p = 0.009]. The rising prevalence of HIV infection and the use of TMP-SMX prophylaxis may alter the spectrum of colonizing and pathogenic bacteria in children in developing countries... - Finger clubbing in children with human immunodeficiency virus infectionH J Zar
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
Ann Trop Paediatr 21:15-9. 2001..7% vs 24.2%, p = 0.035). In geographical areas with high HIV seroprevalence rates, the presence of clubbing in a child hospitalized for respiratory disease should raise the suspicion of HIV infection... - Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South AfricaH J Zar
Department of Paediatrics, University of Cape Town South Africa
Acta Paediatr 90:119-25. 2001..HIV-infected children with pneumonia have a worse outcome than HIV-negative patients... - Pneumocystis carinii pneumonia in South African children infected with human immunodeficiency virusH J Zar
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
Pediatr Infect Dis J 19:603-7. 2000..There is little information on the incidence of PCP in HIV-infected children in Africa... - Lung deposition of aerosol--a comparison of different spacersH J Zar
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, Cape Town, South Africa
Arch Dis Child 82:495-8. 2000.... - Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South AfricaH J Zar
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
Arch Dis Child 82:305-8. 2000..Bacteriological confirmation of pulmonary tuberculosis is difficult in infants and young children. In adults and older children, sputum induction has been successfully used; this technique has not been tested in younger children... - Serum immunoglobulin E levels in human immunodeficiency virus-infected children with pneumoniaHeather J Zar
Department of Paediatrics and Child Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
Pediatr Allergy Immunol 13:328-33. 2002..HIV-infected children with pneumonia have higher serum IgE compared with seronegative patients. In HIV-positive children, IgE levels did not correlate with the degree of immunosuppression or with outcome... - Sputum induction as a diagnostic tool for community-acquired pneumonia in infants and young children from a high HIV prevalence areaH J Zar
School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, South Africa
Pediatr Pulmonol 36:58-62. 2003..In conclusion, induced sputum is a useful and safe diagnostic procedure in infants and children with CAP from a high HIV prevalence area... - Community-acquired pneumonia in HIV-infected children: a global perspectiveD M Gray
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, University of Cape Town, South Africa
Curr Opin Pulm Med 16:208-16. 2010..Pneumonia is a leading cause of morbidity and death in HIV-infected children. The aim of this study was to review recent advances in the epidemiology, cause, management and prevention of pneumonia in HIV-infected children... - Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstructionH J Zar
School of Child and Adolescent Health, Red Cross Children s Hospital, University of Cape Town, Cape Town, South Africa
Arch Dis Child 92:142-6. 2007..Conventional spacers are expensive or unavailable in developing countries, but there is little information on the efficacy of low-cost spacers in young children... - Asthma--is survival good enough?R J Green
Department of Paediatrics and Child Health, University of Pretoria, South Africa
S Afr Med J 97:172-4. 2007 - The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence settingL J Frigati
Department of Paediatrics and Child Health, Red Cross War Memorial Children s Hospital, Klipfontein Road, Rondebosch 7700, South Africa
Thorax 66:496-501. 2011..Strategies to prevent TB in children include isoniazid preventive therapy (IPT) and antiretroviral therapy (ART). IPT and ART have been reported to reduce TB incidence in adults but there are few studies in children... - Induced sputum or gastric lavage for community-based diagnosis of childhood pulmonary tuberculosis?M Hatherill
South African Tuberculosis Vaccine Initiative SATVI, Institute of Infectious Disease and Molecular Medicine IIDMM, University of Cape Town, Cape Town, South Africa
Arch Dis Child 94:195-201. 2009..To compare the diagnostic yield of Mycobacterium tuberculosis from induced sputum (IS) and gastric lavage (GL) among children in a community setting... - Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumoniaH J Zar
School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Rondebosch, South Africa
Clin Infect Dis 39:1047-51. 2004.... - Radiographic features of paediatric pneumocystis pneumonia -- a historical perspectiveR D Pitcher
Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
Clin Radiol 63:666-72. 2008..To establish differences in the radiographic features of PCP documented in HIV-infected children in developed and developing countries... - Guideline for the management of chronic asthma in children--2009 updateC Motala
Division of Allergy, Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children s Hospital, Cape Town
S Afr Med J 99:898-912. 2009..The main aim of the guideline is to promote a better standard of treatment based on understanding of the pathophysiology and pharmacotherapy of asthma, and encouraging uniformity in asthma management... - Changes in fatal and near-fatal asthma in an urban area of South Africa from 1980-1997H J Zar
Dept of Pediatrics and Child Health, University of Cape Town, South Africa
Eur Respir J 18:33-7. 2001..However, the relatively high asthma mortality rate in people of mixed race and the predominance of deaths outside health facilities and on weekends suggest problems with access to care... - Diagnosis and management of community-acquired pneumonia in childhood--South African Thoracic Society GuidelinesH J Zar
School of Child and Adolescent Health, Red Cross Children s Hospital and University of Cape Town
S Afr Med J 95:977-81, 984-90. 2005..The incidence, severity and spectrum of childhood pneumonia have changed owing to the HIV epidemic. Increasing emergence of antimicrobial resistance necessitates a rational approach to the use of antibiotics in pneumonia management... - Guideline for the management of chronic asthma in children - 2009 updateCassim Motala
University of Cape Town
S Afr Med J 99:897-912. 2009..The guideline document was endorsed by the South African Thoracic Society (SATS), the National Asthma Education Programme (NAEP), the South African Paediatric Association (SAPA) and the South African Academy of Family Practice... - Bilateral partial lung lavage in an infant with pulmonary alveolar proteinosisO Hodges
Department of Anaesthesia, Groote Schuur Hospital, Observatory, South Africa
Br J Anaesth 104:228-30. 2010..The infant did not require extra-corporeal oxygenation during the procedure or postoperative ventilation. This method may offer a feasible option for performing lavage in a resource constrained environment... - Prevention of HIV-associated respiratory illness in children in developing countries: potential benefitsH J Zar
School of Child and Adolescent Health, Red Cross Childrens Hospital, University of Cape Town, Cape Town, South Africa
Int J Tuberc Lung Dis 7:820-7. 2003.... - Chest radiographic features of lymphocytic interstitial pneumonitis in HIV-infected childrenR D Pitcher
Division of Paediatric Radiology, Red Cross War Memorial Children s Hospital, Department of Radiation Medicine, University of Cape Town, South Africa
Clin Radiol 65:150-4. 2010.... - Global strategy for asthma management and prevention: GINA executive summaryE D Bateman
University of Cape Town Lung Institute, PO Box 34560, Groote School, 7700 Mowbray, Cape Town, South Africa
Eur Respir J 31:143-78. 2008..The importance of the patient-care giver partnership and guided self-management, along with setting goals for treatment, are also emphasised... - Sputum induction for microbiological diagnosis of childhood pulmonary tuberculosis in a community settingH A Moore
Kuyasa Clinic, Khayelitsha, Cape Town, South Africa
Int J Tuberc Lung Dis 15:1185-90, i. 2011..Sputum induction has increasingly enabled microbiological confirmation of pulmonary tuberculosis (PTB) in hospitalised children, but it has not been evaluated in a community setting... - Chlamydia trachomatis lower respiratory tract infection in infantsH J Zar
Department of Paediatrics and Child Health, University of Cape Town, South Africa
Ann Trop Paediatr 19:9-13. 1999..pneumoniae, S. aureus and N. gonorrhoeae were cultured from five different patients infected with chlamydia. The majority of infants with chlamydial infection had mild disease requiring only outpatient anti- biotic therapy... - Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosisG H Swingler
Division of Paediatric Medicine, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
Arch Dis Child 90:1153-6. 2005..To estimate the diagnostic accuracy of chest radiography in the detection of chest lymphadenopathy in children with clinically suspected pulmonary tuberculosis... - Influenza guideline for South Africa--update 2008R J Green
Department of Paediatrics and Child Health, University of Pretoria, Pretoria
S Afr Med J 98:224-30. 2008....